Vaccine in Sight for Type 1 Diabetes? - Ausmed
And unfounded beliefs such as insulin causing organ damage
Research has been conducted for a number of decades into alternative treatment types for replacing the lost insulin, such as insulin pumps, however they still rely on patients being compliant with treatment. In some cases, insulin pumps are only available to a minority of sufferers such as young children who may not be able to comply with an injection regime.
An ideal alternative would be to block the immune cells from attacking the pancreas, whilst leaving the rest of the immune system untouched but immunosuppressants would leave sufferers more vulnerable to infection.
A vaccine seems to be the most promising solution and something a number of research teams have been working on. Although vaccine research and development is taking place around the world, and has been for quite a while, so far there have been mixed results.
The Pre-Point early vaccination entered its second clinical trial in October 2016.
The vaccine took the form of powdered insulin administered orally with food, to children aged between two and seven. Believing that T1DMmay be prevented by sensitising the immune system to insulin (which is often the first target of the autoimmune response causing the condition), the trial administers the vaccine to children identified as having high risk of developing diabetes, and a positive immune response had been observed in the first stage.
Another promising vaccine study lies with the research funded by Bayhill Therapeutics.
This study was carried out by a team of researchers from Europe, the US, Continue reading