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UT Health San Antonio Team Cures Diabetes In Mice Without Side Effects

UT Health San Antonio team cures diabetes in mice without side effects

UT Health San Antonio team cures diabetes in mice without side effects

SAN ANTONIO, Texas, U.S.A. -- A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.
The discovery, made at The University of Texas Health Science Center, now called UT Health San Antonio, increases the types of pancreatic cells that secrete insulin.
UT Health San Antonio researchers have a goal to reach human clinical trials in three years, but to do so they must first test the strategy in large-animal studies, which will cost an estimated $5 million.
Those studies will precede application to the U.S. Food and Drug Administration for Investigational New Drug (IND) approval, Bruno Doiron, Ph.D., a co-inventor, said.
U.S. patent
The scientists received a U.S. patent in January, and UT Health San Antonio is spinning out a company to begin commercialization.
The strategy has cured diabetes in mice.
"It worked perfectly," Dr. Doiron, assistant professor of medicine at UT Health, said. "We cured mice for one year without any side effects. But it's a mouse model, so caution is needed. We want to bring this to large animals that are closer to humans in physiology of the endocrine system."
Ralph DeFronzo, M.D., professor of medicine and chief of the Division of Diabetes at UT Health, is co-inventor on the patent. He described the therapy:
"The pancreas has many other cell types besides beta cells, and our approach is to alter these cells so that they start to secrete insulin, but only in response to glucose [sugar]," he said. "This is basically just like beta cells."
Insulin, which lo Continue reading

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12 Things You Wish Your Friends Wouldn’t Say About Diabetes

12 Things You Wish Your Friends Wouldn’t Say About Diabetes

Ahh, we love our friends, don’t we? They’ve let us crash on their couch throughout times of transition. They’ve helped us change a flat tire. They’ve been at every birthday celebration you can remember. The really good ones are there to be a shoulder to cry on when times are tough, and to make you laugh until you cry when times are great!
In short, our friends have been there for us, through thick and thin.
But not necessarily when it comes to diabetes.
Why is that? Why is it that when it comes to diabetes, it doesn’t seem that they’re capable of giving support? The answer usually comes down to this: they’re misinformed. It isn’t that they don’t want to give us their support; it’s that they don’t know how. And it’s frustrating, isn’t it? The insensitivity of it all can make you feel like you’re going through life alone, right?
But you’re not. It happens all the time, and to many of us managing our managing our diabetes. So much so, in fact, that it constitutes a list! Below, you’ll find twelve of the most common things we’ve heard from our non-diabetic friends. Check ’em out!
12. “Holy crap, you have to take shots every day? Seriously? Every day?”
11. “My grandma had diabetes. She lost her leg. Then she died. It was awful.”
10. “I need to cut back on my sugar intake, otherwise I’m gonna give myself diabetes, too.”
9. “How do you have diabetes? You look normal.”
8. “Go do that somewhere else. I’ll pass out if I see blood.”
7. “Well, it’s your fault, right, for eating too much and not exercising?”
6. “I don Continue reading

Believe it or not, use frozen lemons and say goodbye to diabetes, tumors, obesity!

Believe it or not, use frozen lemons and say goodbye to diabetes, tumors, obesity!

After reading this article, I’m sure that everyone will want to use frozen lemons!
The healthiest part of all lemons is their skin and peel and most of the times they are thrown away because people do not like their taste. If you use all parts of the lemon, including its skin you can intake 5 to 10 times more the amount of the vitamins and other medical advantages of the lemons.
Lemons are one of the best sources of vitamin C, but also vitamins B6, E, A, as well calcium, iron, riboflavin, phosphorus, folate, magnesium, potassium and protein.
If you use lemons often, you can lose weight, you can prevent diabetes, you can eliminate different types of malignant tumors, you can control hypertension and calm acid reflux and even fever.
Before using a lemon, you should freeze it if you want to get all the medical advantages from it. But, before putting it into the freezer, you first need to clean the lemon and dry it completely. Wait until it is completely frozen and then take it out from the freezer.
When you take out the lemon out of the freezer, cut off one of the ends of the frozen lemon in order for it to be flat. Grind it with the flat side against the grates, just like you do with a piece of cheese. That way you will be free from the danger to slipping it while you are shredding it up.
Then, store the lemon gratings into container or you just use them to enrich the flavor of your meals! You will get exceptionally remarkable sort of flavoring that contrasts from that of squeezing plain lemon juice with the lemony shreds draw out other flavors. Your body will be extremely Continue reading

Diet options for type 2 diabetes: eating plans can vary, study suggests

Diet options for type 2 diabetes: eating plans can vary, study suggests

There isn't a one-size-fits-all approach when it comes to a diet that can prevent and control type 2 diabetes, a recent study suggests.
A review of randomized clinical trials and observational studies on diabetes and nutrition revealed that certain dietary patterns, regardless of weight loss, could help stave off the condition, as well as manage current symptoms better than other diets.
"We undertook this review because we believe that most of the current dietary guidelines for patients with diabetes do not reflect recent evidence," said Osama Hamdy, M.D., Ph.D., Medical Director of Joslin Diabetes Center's Obesity Clinical Program and Assistant Professor of Medicine at Harvard Medical School. "Nutrition can be used as a medicine to prevent and control diabetes in a very effective way."
What should you be eating?
A major finding that is consistent with most research on the topic suggests that a Mediterranean diet, which is rich in whole grains, leafy vegetables and olive oil, is related to a lower risk of diabetes development, even without weight loss. This connection remained intact even when calories were not restricted, the authors found.
Other specific diets that proved beneficial for diabetes prevention and management included low-carbohydrate or low glycemic index diets, which were linked to a lower risk for cardiovascular disease.
Specific foods that were associated with reduced type 2 diabetes risk included leafy green vegetables, oat cereal, yogurt, walnuts, apples, and coffee.
Appropriate healthy fat intake, too, was found to be associated with lower type 2 diabet Continue reading

If You Suffer from Diabetes, Hair Loss, Heart and Joint Inflammation Try This Powerful Fruit

If You Suffer from Diabetes, Hair Loss, Heart and Joint Inflammation Try This Powerful Fruit

The tamarind fruit originates from Asia and Africa, and is often used in the Indian cuisine, where it’s consumed with a combination of salt and pepper. The tamarind has a unique taste, and besides being delicious, it also offers numerous health benefits. Here’s what the fruit can help you treat:
Inflammation in the joints and connective tissues
Inflammation and pain in the connective tissues is common as we age, but you should know that the problem can be controlled by consuming the tamarind fruit. The fruit has powerful anti-inflammatory properties that can reduce the pain and protect the connective tissues, as well as antibacterial properties that can protect your body from infections. The fruit has a rich nutritional profile and contains compounds that can reinforce your immune system, detoxify your body and prevent various ailments.
Improves your eyesight
Tamarind contains a lot of vitamin A which can improve your eyesight and reduce the risk of age-related macular degeneration and other eye problems.
Treats hair loss
Tamarind is one of the best natural remedies against hair loss – just boil it in some water until it softens, then squeeze the fruit to obtain liquid. Apply it on the scalp and rub it in gently, then leave the liquid to work for 60 minutes before rinsing your hair with warm water.
Tamarind can regulate your blood sugar levels and treat diabetes. Buy some tamarind paste at your local health store and mix it with some herbs and jamun – consume the mixture regularly to control your blood sugar levels and prevent diabetes.
Great for your heart
The tama Continue reading

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