Type 1 Diabetes Risk May Come Down To Gut Bacteria Counts

Type 1 Diabetes Risk May Come Down to Gut Bacteria Counts

Type 1 Diabetes Risk May Come Down to Gut Bacteria Counts

Read Stomach Bacteria Could be an Early Type 1 Detector.
Some scientists decided to test whether the environmental conditions at the differing labs affected the rate of non-obese diabetes in the mice, according to Dr. Aleksander Kostic, an assistant investigator at Joslin Diabetes Center in Boston. They raised the mice in a completely sterile, germ-free environment, and found that the rate of non-obese diabetes quickly climbed upwards. They then transferred stool from mice raised in a non-sterile environment to mice raised in a sterile environment, and noticed that the rate of diabetes for the mice who received the transplanted stool went down.
This seemed to indicate that a lack of exposure to microbes was somehow having a severely detrimental effect on the immune system and preventing protection from Type 1 diabetes to mice that were genetically prone, Dr. Kostic said in a phone interview with Insulin Nation.
Read Why People with Type 1 Have Stomach Problems.
Findings like these have given rise to the hygiene hypothesis. This theory supposes that our immune systems are genetically designed to handle a certain load of exposure to microbes. As societys hygiene has improved, it has left the immune system with not enough to do, the theory goes, and it becomes more prone to attacking the body. This could have led to a rise in autoimmune diseases like Type 1 diabetes.
With this theory in mind, Dr. Kostic and others have observed that gut bacteria becomes less diverse in people with Type 1 a year before diagnosis. The guts of people with Type 1 become dominated by several Continue reading

Rate this article
Total 1 ratings
Diabetes: Stimulating bone stem cells may improve fracture repair

Diabetes: Stimulating bone stem cells may improve fracture repair

Diabetes: Stimulating bone stem cells may improve fracture repair
Researchers have discovered a protein that stimulates bone stem cells in mice with diabetes so that the animals heal better after a fracture. They suggest that this could lead to a new treatment to improve bone repair in people with diabetes.
Bones of normal mice (top) form larger calluses during healing, which lead to stronger repair. However, bones of diabetic mice (bottom) have smaller calluses, which lead to more brittle healed bones.
The team, from Stanford University School of Medicine in Palo Alto, CA, reports the findings in the journal Science Translational Medicine.
Michael T. Longaker, a professor of plastic and reconstructive surgery and one of the study's senior authors, sums up the work:
"We've uncovered the reason why some patients with diabetes don't heal well from fractures, and we've come up with a solution that can be locally applied during surgery to repair the break."
Diabetes is a chronic disease that occurs when the body's ability to produce or respond to insulin - a hormone that regulates blood sugar - is impaired.
Raised blood sugar (hyperglycemia) is a common effect of uncontrolled diabetes, and over time it can cause serious damage in many parts of the body, including the heart, blood vessels, eyes, kidneys, and nerves.
Today, there are more than 420 million people with diabetes worldwide - nearly four times as many as there were in 1980 (108 million).
Problematic bone healing is one of the many health complications that people with diabetes experience; following a break Continue reading

Baylor's Lauren Cox has been tender and tough playing with diabetes - Women's college basketball

Baylor's Lauren Cox has been tender and tough playing with diabetes - Women's college basketball

WACO, Texas -- Trying to please the demanding Kim Mulkey and adjusting from high school to elite college basketball at Baylor could lead to a breakdown for any freshman. But Lauren Cox's major freshman issue had nothing to do with any of that. Her misery before Baylor faced Tennessee on Dec. 4 was all because the biggest challenge of her life -- Type 1 diabetes -- threatened to keep her from playing in the game. Her blood sugar levels were dangerously high.
Cox ended up taking the floor in the Baylor win. Her blood sugar returned to the necessary level to allow her to play. Still, she admits it's been incredibly challenging -- dealing with her condition, working to succeed on the court for a top program and trying to be a freshman in college all at the same time.
"It's been pretty tough," Cox said this week, before Baylor faces Louisville in the Sweet 16 on Friday night (ESPN2/WatchESPN, 9 p.m. ET). "Not having my parents there (at Baylor) is definitely a big challenge. Just managing my levels has been pretty tough but I've had a pretty good handle on it."
Natalie Chou can't help the comparisons to Linsanity as she attempts to shatter stereotypes. From pro-style workouts with Jason Terry to navigating her first year at Baylor, this is her story.
On the court, Cox has flashed the potential that made her the top recruit in the country. She has been a key reserve for Mulkey, earning the Big 12 Sixth Man Award while being named to the All-Freshman team after averaging 8.4 points, 4.5 rebounds and 1.6 blocks per game.
That is even more impressive considering Cox has to wa Continue reading

Hybrid closed-loop insulin delivery systems for type 1 diabetes come of age

Hybrid closed-loop insulin delivery systems for type 1 diabetes come of age

At 19 months old, Jamie Kurtzig was diagnosed with type 1 diabetes. For the next 10 years, her parents would wake up every three hours during the night to prick their daughter's finger so they could check her blood glucose level. If her blood glucose was too low, they gave her food to avoid seizures or a loss of consciousness. If it was too high, they gave her an insulin injection to bring the level down to a normal range.
"It's caused a kind of PTSD for my husband and me," said Sara Kurtzig, who lives with her daughter and husband in Marin, California.
But for the past year, they've been able to sleep through most nights. That's because Jamie started using a hybrid closed-loop insulin delivery system in 2016, thanks to a clinical trial at Lucile Packard Children's Hospital Stanford and Stanford Medicine that assessed the system's use in children ages 7 to 14.
"The closed-loop system has completely changed our lives," Sara said. "It took me a month to trust it, but now I can go to bed at 11 p.m. and wake up at 6:30 a.m. almost every night."
The system is among the methods being tested by researchers at the School of Medicine and Lucile Packard Children's Hospital in their efforts to find easier ways for younger children with type 1 diabetes to get the doses of insulin they need.
Bruce Buckingham, MD, professor of pediatric endocrinology, directs clinical trials of the closed-loop system, which modulates insulin delivery based on glucose sensor readings measured every five minutes. He called the system a "historic advance" for diabetes care.
"With this system, patients can a Continue reading

Current study confirms the Nutritarian diet is BEST for reversing type 2 diabetes

Current study confirms the Nutritarian diet is BEST for reversing type 2 diabetes

Current study confirms the Nutritarian diet is BEST for reversing type 2 diabetes
Health Concerns: Diabetes , Type 1 Diabetes , Type 2 Diabetes
For diabetics and pre-diabetics especially, new research proves what moms having been telling their children through the ages, eat your veggies, theyre good for you. A recent study published in the British Journal of Nutrition reported that higher plant protein intake is associated with a reduced risk of type 2 diabetes. In their analysis, they estimated that replacing one percent of calories from animal protein with calories from plant protein would decrease the risk of type 2 diabetes by 18 percent.1
At first glance, it may seem like the dietary effects on diabetes would be only relevant to carbohydrate-containing foods. The more low-carbohydrate, high-protein foods in your diet, the better; those foods dont directly raise blood glucose. However, that is a too simplistic view of the development of type 2 diabetes. Type 2 diabetes is not only driven by elevated glucose levels, but also by chronic inflammation, oxidative stress, and alterations in circulating lipids (fats).2-5
In addition, there has been considerable amount of evidence that red and processed meats are linked to a greater risk of type 2 diabetes This recent study is not the first one to make the connection between protein source and diabetes. In fact, many studies have compared plant and animal protein intake with respect to diabetes risk. A larger study published in 2016 found an increase in type 2 diabetes risk in those with the highest animal protein intake. Continue reading

No more pages to load

Popular Articles

  • Diabetes Drugs Can Alter Intestinal Bacteria

    In recent research, the composition and function of intestinal bacteria has been linked to various problematic health conditions, like diabetes, obesity and even celiac disease. A new study sheds more light on the topic, suggesting that intestinal bacteria may indeed be altered by antidiabetic drugs like metformin - a factor that has not been taken into account before. The research, from the Unive ...

  • Going gluten free may raise your risk of type 2 diabetes

    Celebrities like Gwyneth Paltrow, Victoria Beckham and Miley Cyrus have promoted going gluten free, but new research suggests people without celiac disease or a gluten intolerance may be unnecessarily raising their risk of type 2 diabetes by following the trendy diet. "Gluten-free foods often have less dietary fiber and other micronutrients, making them less nutritious and they also tend to cost m ...

  • Anxiety and Depression May Increase Mortality Risk in Type 2 Diabetes

    Symptoms of anxiety found to be independent of symptoms of depression Type 2 diabetes (T2D) which affects >9% of the population, and depression, which affects >5% of the population, are the leading global causes of morbidity and mortality. Patients with T2D experience depression five-times higher than the general population. Due to the symptomatic similarities between anxiety and depression, they ...

  • Artificial sweeteners may increase risk of type two diabetes, finds study

    INDYPULSE Artificial sweeteners may increase risk of type two diabetes, finds study Consuming artificial sweeteners might raise the risk of developing type two diabetes, new research suggests. The study was conducted by professors at the University of Adelaide in Australia and looked at whether ingesting significant amounts of artificial sweeteners would affect the body’s ability to control gluc ...

  • Just two sugary drinks per week may raise type 2 diabetes risk

    New research — appearing in the Journal of the Endocrine Society — examined 36 existing studies published in the past 10 years to look at the possible effects of sugary drinks on cardiometabolic health. The World Health Organization (WHO) report that at least 19 million yearly deaths are from cardiometabolic disorders – an umbrella term for cardiovascular disease and conditions such as metab ...

  • Gluten-free diets may be tied to an increased risk of Type 2 diabetes

    Gluten-free diets are all the rage, but shunning gluten may offer no benefit to overall health for most people, a new analysis suggests. In fact, the people in the study who ate more gluten were 13 percent less likely to develop Type 2 diabetes over the 30-year study than those who ate less gluten, the researchers found. For some individuals, there are health reasons to avoid gluten, a protein fou ...

  • Low-Fat Dairy May Increase the Risk of Type 2 Diabetes

    A recent study found that people who opted for full-fat dairy products were 50 percent less likely than low-fat fans to develop the disease. For more than a generation, government dietary guidelines have urged Americans to avoid full-fat dairy products. The thinking behind that recommendation is beginning to change, however, and it may shift even more based on recent research suggesting that dairy ...

  • Legumes may lower risk of type 2 diabetes

    Type 2 diabetes is a serious health concern in the United States and across the globe. New research shows that a high consumption of legumes significantly reduces the risk of developing the disease. The legume family consists of plants such as alfalfa, clover, peas, peanuts, soybeans, chickpeas, lentils, and various types of beans. As a food group, they are believed to be particularly nutritious a ...

  • Mediterranean diet may help reduce risk of Type 2 Diabetes

    An estimated 86 million Americans are at risk for Type 2 Diabetes, but nearly 90 percent of them don’t know it. Doctors say adhering to a Mediterranean diet may help to reverse your risk of developing Type 2 Diabetes. The Mediterranean diet, which is especially popular from Spain and Italy to Greece and the Middle East, largely focuses on seasonal fruits and vegetables. “It’s dark leafy gree ...

Related Articles