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The Gut Microbiome As A Target For Prevention And Treatment Of Hyperglycaemia In Type 2 Diabetes: From Current Human Evidence To Future Possibilities

The gut microbiome as a target for prevention and treatment of hyperglycaemia in type 2 diabetes: from current human evidence to future possibilities

The gut microbiome as a target for prevention and treatment of hyperglycaemia in type 2 diabetes: from current human evidence to future possibilities


, Volume 60, Issue6 , pp 943951 | Cite as
The gut microbiome as a target for prevention and treatment of hyperglycaemia in type 2 diabetes: from current human evidence to future possibilities
The totality of microbial genomes in the gut exceeds the size of the human genome, having around 500-fold more genes that importantly complement our coding potential. Microbial genes are essential for key metabolic processes, such as the breakdown of indigestible dietary fibres to short-chain fatty acids, biosynthesis of amino acids and vitamins, and production of neurotransmitters and hormones. During the last decade, evidence has accumulated to support a role for gut microbiota (analysed from faecal samples) in glycaemic control and type 2 diabetes. Mechanistic studies in mice support a causal role for gut microbiota in metabolic diseases, although human data favouring causality is insufficient. As it may be challenging to sort the human evidence from the large number of animal studies in the field, there is a need to provide a review of human studies. Thus, the aim of this review is to cover the current and future possibilities and challenges of using the gut microbiota, with its capacity to be modified, in the development of preventive and treatment strategies for hyperglycaemia and type 2 diabetes in humans. We discuss what is known about the composition and functionality of human gut microbiota in type 2 diabetes and summarise recent evidence of current treatment strategies that involve, or are based on, modification of gut microbiota (diet, probiotics, metformin and bariatri Continue reading

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At Risk for Diabetes? | Wellmark Blue

At Risk for Diabetes? | Wellmark Blue


Add up your score and check below to see what it means.
This means your risk is probably low for having prediabetes now. Keep your risk low. If youre overweight, increase your activity and eat low-fat meals with fruits, vegetables and whole-grain foods, and dont use tobacco. If you have high cholesterol or high blood pressure, talk to your health care provider about your risk for type 2 diabetes.
This means your risk is high for having prediabetes now. Please make an appointment with your health care provider soon.
As we age, its normal to expect wrinkles and thinning hair. There are other things, however, we shouldnt assume are normal parts of aging. For example, high cholesterol, high blood pressure, and high blood sugar.
But with the right diet and level of physical activity, you can avoid many health problems associated with aging.
Theres a simple term for certain diseases before they become the full-blown version of a disease: pre-disease. Pre-disease means you dont currently have a disease, but youre headed toward one.
"The biggest difference between prediabetes and diabetes is that prediabetes is reversible. Diabetes is not."
Megan MuozRN, MSN, and Certified Diabetes Educator
Pre-disease is like coming to a fork in the road. Its time to make a choice. You can make changes to your lifestyle and stop or delay the onset of a chronic disease. Or, you can change nothing and be highly prone to develop a lifelong disease that will impact every part of your life, says Megan Muoz, RN, MSN, and certified diabetes educator at UnityPoint Health Clinic in Cedar Rapids, Continue reading

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KINGS Herbal | REH KINGS Herbal Official website | Ka Rey Herrera KINGS Herbal - one of leading herbal food supplement in the Philippines | Herbal supplement best for diabetes, hypertension, cancer, kidney stone and various diseases and illnesses


Diabetes frightens us. Not just because its a disease that has fatality rates higher than cancer but also because we have a sweet tooth, and cannot live without sweets. Well, before this, little did we know that diabetes doesnt always mean that you have to abandon the sweet-ship altogether. Healthy eating is everything. Now lets get to the facts.
However, people who have close relatives with the disease are somewhat more likely to develop it. Other risk factors include obesity, high cholesterol, high blood pressure, and physical inactivity. The risk of developing diabetes also increases as people grow older. People who are over 40 and overweight are more likely to develop diabetes, although the incidence of type 2 diabetes in adolescents is growing. Also, people who develop diabetes while pregnant (a condition called gestational diabetes) are more likely to develop full-blown diabetes later in life.
2. It doesnt mean because your skinny or lean, you cant have diabetes.
You might imagine the typical type 2 patient to be heavy and inactiveand think youre in the clear if you dont fit that description. But more and more, the condition is becoming a problem for the young and thin, too. About 15 percent of people with type 2 diabetes arent overweightbut that doesnt mean that theyre healthy. The culprit is what has become known as skinny-fat. You might look healthy on the outside, but any number of unhealthy habits will have your insides behaving as if you are obeseputting you at risk of developing diabetes.
3. There are two major types of diabetes.
In type 1 (formerly call Continue reading

Entertainment mogul Damon Dashs new Dash Diabetes Network is all about healthy living

Entertainment mogul Damon Dashs new Dash Diabetes Network is all about healthy living


Entertainment and media veteran Damon Dash is now in the business of advocating for others to adopt and maintain a healthy lifestyle and a better quality of life.
The star was diagnosed with Type 1 diabetes when he was 15 years old. Shortly afterward, he lost his mother to asthma. Thats his motivation for his new venture: the Dash Diabetes Network .
Diabetes appears in two forms, each of which affects the bodys ability to maintain insulin levels. In Type 1 diabetes, the pancreas is unable to create insulin at all, while Type 2 happens when the body struggles to control glucose levels.
According to the American Diabetes Association (the focus of a sharp Netflix documentary What the Health, named for the groups failure to provide proper dietary information by diabetes risk factors rather than the general population), African-Americans are disproportionately affected by diabetes. With 13.2 percent of all African-Americans age 20 or older diagnosed with diabetes, black people are 1.7 times more likely to have diabetes as non-Hispanic whites. The website also notes that African-Americans are significantly more likely to suffer complications common to diabetes, such as blindness, kidney disease and amputations.
That being said, millions of diabetic Americans live healthy and uninhibited lives maintaining their diabetes, and the 40-year-old credits What the Health for prompting him to make some serious dietary changes.
If the multilayered Dash had a traditional resume, it would list a wide variety of accomplishments. Music and entertainment executive check. Talent discover Continue reading

How to Survive Halloween When You Have Diabetes

How to Survive Halloween When You Have Diabetes


How to Survive Halloween When You Have Diabetes
Expert tips for helping your T1D child have fun on a day devoted to candy!
Written by Erin Palinski-Wade, RD, CDE, LDN
It's hard to believe that Halloween is a week away. No doubt you noticed the stockpile of holiday candies lining store shelves starting early last month. Perhaps these goodies have even begun to make their way into your workplace and home. When you have to monitor your carbohydrate intake to manage healthy blood sugar levels, it can seem like Halloween time is a surefire ways to derail your efforts.
Monster Mouths: Apple slices, plus peanut or almond butter and a handful of yogurt covered raisins. Or use slivered almonds instead of raisins to lower the glycemic load.
But dont stress. With a few easy tricks you will see more of a treat on the screen of your glucose monitor rather than a scary number. Here's how:
#1. Keep Halloween candy under wraps as much as possible.
Do you remember when you were a child what would happen when you saw a bowl of candy somewhere? You most likely wanted a piece (or two, or three!). Well, this doesn't change just because you are an adult. When you see a bowl of candy that you like within arms reach, chances are you're going to want to dig in.
Even if you resist the urge to indulge, the more often you see the candy, the more likely you will be to eventually break down and eat some. This is especially true if you see the candy during times of high stress, such as a bowl of candy on your desk at work. If coworkers, roommates, or spouses insist on keeping Halloween-themed Continue reading

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