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The Effect Of Walking On Postprandial Glycemic Excursion In Patients With Type 1 Diabetes And Healthy People

The Effect of Walking on Postprandial Glycemic Excursion in Patients With Type 1 Diabetes and Healthy People

The Effect of Walking on Postprandial Glycemic Excursion in Patients With Type 1 Diabetes and Healthy People

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Abstract
Physical activity (PA), even at low intensity, promotes health and improves hyperglycemia. However, the effect of low-intensity PA captured with accelerometery on glucose variability in healthy individuals and patients with type 1 diabetes has not been examined. Quantifying the effects of PA on glycemic variability would improve artificial endocrine pancreas (AEP) algorithms.
We studied 12 healthy control subjects (five males, 37.7 ± 13.7 years of age) and 12 patients with type 1 diabetes (five males, 37.4 ± 14.2 years of age) for 88 h. Participants performed PA approximating a threefold increase over their basal metabolic rate. PA was captured using a PA-monitoring system, and interstitial fluid glucose concentrations were captured with continuous glucose monitors. In random order, one meal per day was followed by inactivity, and the other meals were followed by walking. Glucose and PA data for a total of 216 meals were analyzed from 30 min prior to meal ingestion to 270 min postmeal.
In healthy subjects, the incremental glucose area under the curve was 4.5 mmol/L/270 min for meals followed by walking, whereas it was 9.6 mmol/L/270 min (P = 0.022) for meals followed by inactivity. The corresponding glucose excursions for those with type 1 diabetes were 7.5 mmol/L/270 min and 18.4 mmol/L/270 min, respectively (P < 0.001).
Walking significantly impacts postprandial glucose excursions in healthy populations and in those with type 1 diabetes. AEP algorithms incorporating PA may enhance tight glycemic control end points.
Box plots of area under the curve (A), Continue reading

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HIIT exercise will reduce your diabetes risk | Daily Mail Online

HIIT exercise will reduce your diabetes risk | Daily Mail Online


High intensity interval training (HIIT)combats high insulin resistance
Women at risk for diabetes showed lower glucose levels after 10-week course
A different study found intensive exercise and a strict diet brought big benefits
Half of diabetes patients no longer needed their glucose-lowering medications
When it comes to reducing the risk of diabetes - or managing the condition if you already have it - there's a consistent message in some camps: a little exercise is always better than none.
But now new research has revealed that a gentle walk here and there is not enough to prevent or controlling it - high intensity interval training (HIIT) is what works.
One new study has found that this type - which involves short burst of high-intensity exercise followed by a brief low-intensity activity, repeatedly - combats high insulin resistance, a warning sign for the chronic disease.
The finding comes as another study discovered that a programme of intensive exercise and a strict dietworked so well that half of participants no longer needed their glucose-lowering medications.
Research suggests high-intensity exercise combats high insulin resistance, which is a warning sign for diabetes (file photo)
However, not all experts agree and one warned that diabetics should not come off their drugs and advised that a healthy lifestyle should always be adopted in combination with medication.
Exposure to light at night-time increases womens risk of breast cancer by up to 14% by disrupting a protective hormone
In the first study, a team led by Professor Mikel Izquierdo from t Continue reading

Proper Magnesium Intake Prevents Heart Diseases, Diabetes and Stroke

Proper Magnesium Intake Prevents Heart Diseases, Diabetes and Stroke

Summary:
According to a new study, high amount of magnesium intake lowers the heart risks, stroke, and diabetes type 2.
Scientists ignored the fact that lack of magnesium is the reason of atherogenesis and different heart issues. The focus was on the wrong reasons: cholesterol and saturated fats.
Unequal consumption of magnesium and calcium increases the chances of getting a heart disease.
The cardiovascular diseases are the primary reason for death in the USA, while doctors paid attention to cholesterol and statins prescription over a period of 20 years.
According to a new study, if you want to lower the possibility of getting a CHD, stroke, or diabetes type 2, you should add plus 100 mg of magnesium to your daily diet. This is just a simple way to get excellent results.
Over 1 million humans from 9 countries who took extra magnesium, got results with a 10% decreased the risk of developing CHD, 26 % decreased risk of diabetes type 2, and a 12 % decreased risk of getting a stroke. This information was discovered by investigators from University of Zhejiang and University of Zhengzhou, located in China.
The head of the study published in Biome Central, Fudi Wang, PhD, gives an explanation of the risks of low magnesium intake. He says that lack of magnesium in the organism is linked to many diseases. However, there is still no final evidence about the connection between magnesium and possible health harm.
Also, Wang says that their study results show a connection between the effect of magnesium in diet and lowering the chance of getting some disease. Their discoveries would h Continue reading

These viruses may skew children’s odds of diabetes

These viruses may skew children’s odds of diabetes

Viruses in the intestines may affect a person’s chance of developing type 1 diabetes, report researchers.
Children whose gut viral communities, or viromes, are less diverse are more likely to generate self-destructive antibodies that can lead to type 1 diabetes. Further, children who carried a specific virus belonging to the Circoviridae family were less likely to head down the path toward diabetes than those who carried members of a different group of viruses.
“We identified one virus that was significantly associated with reduced risk, and another group of viruses that was associated with increased risk of developing antibodies against the children’s own cells,” says senior author of the study Herbert “Skip” Virgin IV, professor and head of pathology and immunology at Washington University School of Medicine in St. Louis.
“It looks like the balance of these two groups of viruses may control the risk of developing the antibodies that can lead to type 1 diabetes.”
The findings, published online in the Proceedings of the National Academy of Sciences, suggest a way to predict, and maybe even prevent, the life-altering diagnosis.
Type 1 diabetes develops as a two-step process. First, a person acquires antibodies against cells in the pancreas responsible for producing insulin, a hormone that allows cells to absorb sugar from the bloodstream so they can burn it for energy. Some children generate the antibodies—called auto-antibodies because they target the person’s own cells—but never go on to develop disease.
In other children, however, the auto-antibodies Continue reading

Interim results of first-ever global survey show people with type 2 diabetes underestimate their cardiovascular risk

Interim results of first-ever global survey show people with type 2 diabetes underestimate their cardiovascular risk

Today the International Diabetes Federation (IDF) presented the interim results of the first ever multi-country online survey on CVD risk awareness and knowledge among people living with type 2 diabetes, indicating low levels of awareness and limited dialogue between patients and healthcare professionals. The global survey - Taking Diabetes to Heart - developed in partnership with Novo Nordisk, runs until March 2018 and is open to all people with type 2 diabetes.
Diabetes currently affects 425 million adults worldwide(1), with most cases being type 2 diabetes. Cardiovascular disease, which includes stroke, coronary heart disease and peripheral artery disease(3), is the leading cause of disability and death in people with type 2 diabetes(1,4).
To date, 943 responses to the survey have been received from 32 countries and interim findings show that:
1 in 3 respondents living with type 2 diabetes consider their risk of CVD to be low2
26% of respondents had either never learned about CVD or received information on CVD several years following their type 2 diabetes diagnosis2
1 in 6 respondents had never discussed their type 2 diabetes and CVD risk with a healthcare professional2
"The interim results of Taking Diabetes to Heart reiterate the importance of raising awareness of the association between type 2 diabetes and cardiovascular disease to promote prevention, timely diagnosis and appropriate treatment to help reduce the current burden that the two conditions represent," said Dr Shaukat Sadikot, outgoing IDF President. "With the world facing an increase in the prevalence of ty Continue reading

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