Taking blood pressure drugs at night wards off diabetes, study finds
(Mike Derer / Associated Press)
Sometimes, disease-prevention really is this simple: Adults with high blood pressure who take all of their hypertension medications before they go to bed, rather than in the morning, are less likely to develop Type 2 diabetes, new research has found.
The new findings are in line with other insights gleaned by the same investigators: that hypertension patients who are most at risk of developing diabetes -- and cardiovascular disease -- are those whose blood pressure fails to show a substantial dip during sleep.
It stood to reason, then, that a medication regimen that more tightly controls a hypertensive's blood pressure while he or she sleeps might help to at least forestall the development of Type 2 diabetes.
In a large clinical trial conducted in Spain and published Wednesday in the journal Diabetologia, that hypothesis turned out to be true. And effecting such tight nighttime blood-pressure control turned out to be as simple as having subjects take their hypertension drugs -- whether ACE inhibitors, angiotensin-receptor blockers or beta blockers -- before they turned in for the night.
A drop in blood pressure is normal while sleeping. But not all people see such a dip while they sleep, and some see more shallow dips.
A second trial, also published in Diabetologia on Wednesday and conducted by the same group of Spanish researchers, found that subjects whose blood pressure did not dip, and those whose readings dipped more briefly or shallowly, were more likely to develop Type 2 diabetes than those whose sleep-time blood pressure saw a deep an Continue reading