
Take Statins? What You Need to Know about Diabetes Risk
Statin medications (statins) are drugs that help lower cholesterol levels in the blood to help prevent coronary heart disease for those at risk or who already have experienced some form of cardiovascular disease. Statins do carry certain risks that need balanced and managed through ongoing physician monitoring. A recent study highlights how important it is to manage diabetes risk factors when taking statins.
New study examines statin-diabetes link
A higher than previously documented risk of Type 2 diabetes with statin use was recently reported in the journal Diabetologia. Various past studies have found a zero to 36 percent higher risk of developing diabetes while taking statins. An average risk of developing diabetes on statins is reported at approximately 9% in meta-analyses.
This latest study determined that men taking statins had a 46 percent higher risk of diabetes than those not on statins. Additionally, statin use was associated with a 24 percent reduction in insulin sensitivity and a 12 percent reduction in insulin secretion. Some previous studies evaluated fasting blood sugar, while this study applied more precise A1C and glucose tolerance tests.
Michael Rocco, MD, Medical Director of Cardiac Rehabilitation and Stress Testing, Section of Preventive Cardiology at Cleveland Clinic, reviewed the findings (he did not participate in the research). Dr. Rocco noted that the people who developed diabetes while taking statins were older, had a higher Body Mass Index (BMI), and a much higher incidence of cardiovascular disease.
“It does look like people who have increased
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