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Symptoms At Diagnosis May Predict Progression Of Type 2 Diabetes

Symptoms at Diagnosis May Predict Progression of Type 2 Diabetes

Symptoms at Diagnosis May Predict Progression of Type 2 Diabetes

Researchers followed patients who were newly diagnosed with type 2 diabetes for 18 months to classify their disease progression based on 20 baseline symptoms.
With Caroline A. Brorsson, PhD, and Michael Gonzalez-Campoy, MD, PhD
Three major subgroups of newly diagnosed patients with type 2 diabetes (T2D) experienced different rates of disease progression over 18 months,1 according to data presented at the 53rd annual meeting of the European Association for the Study of Diabetes in Lisbon, Portugal. The research was part of the Diabetes Research on Patient Stratification project (DIRECT) within the European Union Framework 7 Innovative Medicines Initiative.
Patients with type 2 diabetes are likely to present with varying degrees of insulin resistance and beta cell failure.1 Understanding the heterogeneity of a T2D presentation may lead to more effective treatment strategies for these patients. An underlying difference in pathophysiology may be indicative of a patient’s responsiveness to a prescribed treatment and have an anticipated effect on disease progression.1
Evaluating Differences in Diabetes Progression
Caroline Brorsson, PhD, a postdoctoral researcher at the Technical University of Denmark and colleagues used the detailed clinical phenotyping from the Diabetes Remission Clinical Trial (DIRECT) to identify and cluster subgroups of patients who were newly diagnosed with T2D.1,2 In the DIRECT study, detailed metabolic data were collected on patients newly diagnosed with either prediabetes or type 2 diabetes.2
“Using a very detailed clinical phenotyping methodology, w Continue reading

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Berberine: A Supplement for Diabetes as Good as a Drug?

Berberine: A Supplement for Diabetes as Good as a Drug?


Berberine: A Supplement for Diabetes as Good as a Drug?
Berberine: A Supplement for Diabetes as Good as a Drug?
The Centers for Disease Control and Prevention (CDC) has declared diabetes an American epidemic with more than 25 million Americans afflicted with diabetes. Another 80 million are classified prediabetic, per the American Diabetes Association. The numbers get even bigger when you put a dollar sign in front of them: As of 2012, $245 billion a year was being spent on diabetes in the U.S., including $176 billion in direct medical costs and the rest -- $69 billion in lost productivity.
Its no wonder that pharmaceutical companies remain fully engaged in diabetes-related research, devising new medications and enhancing the older ones looking for a cure. Among the drugs now being used for type 2 diabetes are metformin, sulfonylureas (which goes by the trade names Diabeta and Glucotrol, among others) and DPP-5 inhibitors (Januvia, Tradienta, etc.). All have been shown to be effective to one degree or another, but the epidemic continues to beg for new and improved drugs.
One of the great new hopes in the world of diabetes treatment is a natural plant-based compound that has been used for thousands of years in traditional Chinese and Ayurvedic medical practice. However, it has only become a part of Western medicine in recent years. Most of the attention on berberine, at least in the U.S., encompasses only the 21st century. In that sense, our newest discovery means we are just now catching up with the rest of the world.
Note to readers: Wonder Labs will have a special Continue reading

Diabetes and Alcohol: to drink or not to drink

Diabetes and Alcohol: to drink or not to drink


Diabetes and Alcohol: to drink or not to drink
The life of a diabetic is full of challenges and they have to face it in each and every day of their lives. Each day seems like a struggle and this tussle takes a heavy toll on diabetic physically and emotionally.
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One of the major concern among diabetic is what kind of items they can have and what needs to be avoided. And with this problem, a question arises of diabetes and alcohol relationship;
Are they prone to more risk of complication with alcohol?
What is the safe limit for a diabetic to have alcohol?
A large chunk of population consume alcohol in some form or another;
Consumption of alcohol is only rising due to stressful life and increased depression related cases;
Our films have also promoted alcohol intake, they have developed a sense of perception that late night partying and boozing around is a way for happy and successful life;
Reports claiming health benefits of alcohol have confused people whether it is good or bad for health;
Before coming to a straight answer, we should understand how our body reacts with alcohol intake.
The food we eat get metabolize and digested in thestomach.
But the case is different with alcohol; our liver is responsible for Alcohol metabolism.
1. It stores and secretes glucose to cells in order to fuel them when we are not eating
So whenever we take alcohol, it is not considered as food by our stomach but identified as toxic Continue reading

Diabetes-Friendly Fun and Education at the ADA Expo

Diabetes-Friendly Fun and Education at the ADA Expo


The American Diabetes Association invites you to join them at their annual Health and Wellness Expo on April 8th, 2017 in Chicago, Illinois. This event is FREE and promises lots of fun, games and diabetes education for the entire family! This year, American Medical ID has donated over 200 diabetes bracelets that will be given to EXPO attendees to help educate on the importance of wearing a Medical ID.
Mallory Dahlquist, Manager- Community Health Strategies with the ADA Illinois Chapter, answered many of our questions about the upcoming event.
Tell us a little bit about the event: On April 8th, 2017 the American Diabetes Association will host its 14th Annual Health & Wellness EXPO, presented by Meridian, at the McCormick Place from 10am-3pm. This free event includes activities for people of all ages, including a Family Fun Zone with information for the whole family. The Health & Wellness EXPO provides the community with a unique opportunity to receive free health screenings, participate in healthy cooking demonstrations, learn more about active living, speak with over 50 exhibitors and listen to leading experts talk about diabetes, prevention, management and breakthrough technologies.
What is the Family Fun Zone? What are some of the activities?The Family Fun Zone is a space at the Health & Wellness EXPO with information, activities, and resources for those at the EXPO under the age of 18 years old and their family. In the Family Fun Zone, kids will participate in a Diabetes Clinic and get the chance to adopt a stuffed animal with diabetes, and have to visit stations to Continue reading

Formula made with cows milk does not increase diabetes risk

Formula made with cows milk does not increase diabetes risk


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A 15-year global study of children genetically predisposed to developing Type 1 diabetes found that drinking formula made with cows milk did not increase their risk for developing the disease.
A 15-year global study of children genetically predisposed to developing Type 1 diabetes found that drinking formula made with cows milk did not increase such childrens risk for developing the disease.
The findings provide a long-awaited answer to the question of whether infant formula made with cows milk plays a role in the development of Type 1 diabetes, according to an international team of researchers that includes scientists at Washington University School of Medicine in St. Louis.
The findings are published Jan. 2 in JAMA.
Previous studies have indicated that early exposure to complex foreign proteins, such as the proteins in cows milk, may increase the risk of Type 1 diabetes in people with genetic risk for the disease, said one of the studys authors, Neil H. White, MD , a Washington University professor of pediatrics and of medicine. The question was whether delaying the exposure to complex foreign proteins will decrease the risk of diabetes. The answer is no.
In the U.S., about 200,000 youth under the age of 20 have Type 1 diabetes, an autoimmune disease caused when the pancreas stops producing the hormone insulin, which regulates the bodys blood-sugar levels.
Beginning in 2002, White and his research colleagues examined 2,159 infants in 15 countries. Each infant had a family member affected by Type 1 diabetes, as well Continue reading

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