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Stabilizing Diabetes: Old Drug Could Help Millions

Stabilizing diabetes: Old drug could help millions

Stabilizing diabetes: Old drug could help millions

Dr. Denise L. Faustman is testing a cheap “penny vaccine” that could bring hope to millions struggling with Type 1 diabetes.
The researcher from Massachusetts General Hospital said BCG — a vaccine used against tuberculosis that’s been around since 1921 — could reverse the deadly effects of the disease.
“This offers hope for the first time that people with the long-standing disease will have long-term benefits,” Faustman told the Herald last night. “And to think it’s due to a cheap, 100-year-old generic drug.”
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Diabetes: can you really eat to beat it?

Diabetes: can you really eat to beat it?

Just over four years ago, my GP gave me unwelcome news: I had type 2 diabetes. I was shocked. I didn’t match the stereotypical patient profile of an overweight couch potato. Aged 59, I was thin, fit and 5ft 7in tall, drank frugally, went running every week and weighed just 10st 7lb. The outlook was not good, with the risk of heart attacks, strokes, blindness, amputations and a 36% greater chance of dying early. I thought, this can’t be happening to me; there has to be a way through. I started trawling the web for information and unearthed a report about a research trial at Newcastle University, led by Professor Roy Taylor.
The results suggested you could reverse type 2 with a daily 800-calorie diet for eight weeks, depending on how quickly and how much weight you need to lose. Taylor’s team discovered that type 2 is caused by fat clogging up the pancreas, preventing it from producing sufficient insulin to control blood sugar level. They calculated you need to reduce your pre-diagnosis body weight by a sixth to starve your body into using up the rogue fat lodged in your pancreas and allow it to function normally. “The body does not like any fat lying around in the pancreas, so it consumes that first,” says Taylor. The daily 800-calorie diet comprises either three 200g liquid food supplements of soups and shakes, and 200g of non-starchy vegetables or the tastier 800g equivalent of calorie-shy meals you measure out yourself, plus 2-3 litres of water.
It sounded tough, but what could I lose? I chose the supplement route. It was like a leap in the dark – I’d always Continue reading

How to Lose Weight and Prevent Diabetes Before It’s Too Late

How to Lose Weight and Prevent Diabetes Before It’s Too Late

Weight loss expert and digestive health surgeon Bipan Chand, MD, has devoted his career to treating obese patients, many of whom are diabetic or at high risk of developing type 2 diabetes. We asked Dr. Chand to explain why weight loss is important to preventing type 2 diabetes and to share the best strategies for losing weight.
In the United States, type 2 diabetes is predominantly related to obesity. So someone who is obese and is trying to control a prediabetic condition should focus on weight loss.
With excess fat, especially around the waist, the body has greater difficulty processing sugar and becomes resistant to insulin. As that happens, the level of sugar in the blood rises.
Someone whose blood sugar level is higher than normal (>100) but not too high is said to have prediabetes. That fasting blood sugar level is a snapshot of how your body is processing sugar at that one time. It’s a reasonable screening tool, but obesity is a more important factor.
An increasing Body Mass Index and growing waist size are better predictors of prediabetes. Insulin resistance and diabetes develop over years. Someone with a family history of diabetes and a high BMI for many years probably already has impaired pancreas function. So they may have had diabetes three to five years before it is diagnosed.
Taking action
Each January, many people make New Year’s resolutions to lose weight. That is the wrong idea. You should not make a resolution. You should make a decision to review your health, work to improve it and commit to making long-term changes.
The best strategy to prevent diabe Continue reading

Boston Children’s Hospital Finds Root Cause of Diabetes

Boston Children’s Hospital Finds Root Cause of Diabetes

They say that with just a little more study, they could possibly cure type 1 diabetes.
Boston Children’s Hospital could be on the verge of curing type 1 diabetes. Seriously. This huge news, which was announced today on their blog, could affect the 215,000 people in the U.S. younger than 20 who have diabetes (type 1 or type 2). That’s a pretty huge number, so it’s no wonder why it’s been called an epidemic.
People who live with type 1 diabetes have to inject themselves with insulin to regulate the glucose in their blood. It’s an immediate fix, but there are many long-term complications associated with diabetes, like heart and kidney diseases, nerve problems, skin issues, and problems with vision, among others. “Insulin injections can manage hyperglycemia by reducing the patient’s glucose levels, but it is not the cure,” says Dr. Paolo Fiorina of the Nephrology Division at Boston Children’s Hospital in the report. The Nephrology Division was recently ranked number one in the country by U.S. News and World Report.
Fiorina was looking for the molecular pathway that triggers diabetes, hoping to find better treatment options with the ultimate goal of finding a permanent cure. “In order to truly cure diabetes, we needed to pinpoint exactly why this happens. And then prevent it,” Fiorina says.
According to Boston Children’s Hospital, Fiorina and his team found the root cause of type 1 diabetes:
Fiorina and his team studied hundreds of pathways in animals with diabetes. They eventually isolated one, known as ATP/P2X7R, which triggers the T-cell attacks on the Continue reading

Doctor Explains How Reversing Type 2 Diabetes Starts With Ignoring The Guidelines On Carbohydrates

Doctor Explains How Reversing Type 2 Diabetes Starts With Ignoring The Guidelines On Carbohydrates

Obesity is a life-threatening disease not taken on by choice. Yet, thanks at least in part to our society’s glorification of thinness, many have preconceived notions about those who are obese, believing they are to blame for their situation — that they are simply lazy, gluttonous, and lack the willpower to change.
But as Sarah Hallberg, the Medical Director of the Medically Supervised Weight Loss Program at IU Health Arnett, United States, notes, obesity is a hormonal disease, not a lifestyle choice. And one of those hormones is insulin.
The body processes insulin when glucose is released into the bloodstream following carbohydrate consumption. Usually, this insulin responsF
As for the general recommendations put forth by the American Diabetes Association (ADA), she explains that, “The general recommendations are to tell patients with type 2 to consume 40-65g of carbohydrate per meal, plus more at snacks. We are essentially recommending that they eat exactly what’s causing their problem.”
Hallberg notes that, when treating type 2 patients with insulin, glucose levels rise after eating carbs, as does the need for insulin. But because insulin is the body’s fat storage hormone, this causes hunger fat to be stored, making it difficult for patients to lose weight.
“The ADA guidelines specifically state that there is inconclusive evidence to recommend a specific carbohydrate limit. Nowhere in the ADA guidelines is the aim of reversing type 2 diabetes. This needs to be changed because type 2 can be reversed, in many if not most situations, especially if we start earl Continue reading

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