Research Spotlight – Putting Type 2 Diabetes Into Remission

Research spotlight – putting Type 2 diabetes into remission

Low-calorie weight management programmes
Our scientists are busy researching a new weight management treatment, which includes a low-calorie diet, to help people put their Type 2 diabetes into remission. The study is called DiRECT, short for Diabetes Remission Clinical Trial, and it could completely change the way Type 2 diabetes is treated in the future.
A year into the research and we've made a breakthrough – and we’re excited to share the news with you.
Here's Tony talking about being in the study and Professor Roy Taylor revealing what the results could mean.
Results so far
The first year results are hugely promising. They show that it’s possible for some people to put their Type 2 diabetes into remission using a low-calorie, diet-based, weight management programme, delivered by their GP. Almost half (45.6%) of those who took part in the programme were in remission after a year.
The study found there was a close link between Type 2 diabetes remission and total weight loss. 86% of people who lost more than 15kg on the programme were in remission after a year, as were 57% of people who lost 10 to 15kg, and 34% who lost 5 to 10kg.
In the comparison group, where people had the best diabetes care currently available, but didn't try the new weight management approach, only 4% went into remission.
But what does remission actually mean? It’s when blood glucose (or blood sugar) levels are in a normal range again. This doesn’t mean diabetes has gone for good. It’s still really important for people in remission to get regular healthcare checks, so any complications can Continue reading

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5 Reasons to Test Your Dog for Diabetes

Did you know that some authorities feel that 1 out of every 100 dogs that reaches 12 years of age develops diabetes mellitus1?
Diabetes mellitus (DM) is a hormonal problem where the pancreas fails to produce enough insulin, the hormone that helps push sugar (“glucose”) into the body’s cells. Without the insulin, the body’s cells are starving for sugar; unfortunately, this then stimulates the body to produce more and more sugar (in an attempt to feed the cells). That’s why your dog’s blood sugar is so high (what we call a “hyperglycemia”) with diabetes mellitus.
Without insulin, the sugar can’t get into the cells; hence, why you need to give insulin to your dog with a tiny syringe twice a day. In dogs, this is a disease that can be costly to treat and requires twice-a-day insulin along with frequent veterinary visits for the rest of your dog’s life.
So how do you know if your dog has diabetes? Clinical signs of diabetes mellitus in dogs include:
Dilute urine
Muscle wasting
Ravenous appetite
Frequent urinary tract infections
Weakness
Unkempt or poor hair coat
Blindness secondary to cataracts
Neuropathies (nerve problems)
As your dog gets older, it’s worth talking to your veterinarian about doing routine blood work to make sure your dog is healthy. This blood work will help rule out kidney and liver problems, anemia, infections, electrolyte problems and diabetes mellitus. The sooner you recognize the clinical signs, the sooner your dog can be treated with insulin and the less complications we see as a result.
So, if you notice any of the signs above, get Continue reading

Top 8 Spices and Herbs for Type 2 Diabetes

Human life expectancy continues to rise in many parts of the world, a fortunate event with some unfortunate results. Dr. Ahmad Shamim notes in his book about diabetes that an older population and increase in obesity have been linked to a global rise in type 2 diabetes. The numbers estimate that without a cure, a global increase will lead to around 439 million diabetics by 2030.
Living with diabetes, however, is getting much easier. Thanks to many medical studies, researchers are finding ways to live a long and healthy life with diabetes. The following herbs and spices have been in the spotlight in recent decades for their ability to help a diabetic control their condition.
1. Cinnamon
As an herb known mainly for baking sweets, cinnamon doesn’t get as much credit as it should within the medical community. This spice is packed with antioxidants, antibacterial properties, anti inflammatory properties, and the ability to help people with diabetes. Ceylon Cinnamon is the best choice as this type of cinnamon is more closely associated with potential health benefits involving blood sugar regulation.
Research has displayed cinnamon’s ability to lowering the body’s resistance to insulin and decrease overall cholesterol levels within people that have type 2 diabetes. It can be ingested in the powdered spice form or taken as a supplement (consult with your doctor before taking cinnamon, or other herb, in a supplement form). Due to the lower sugar levels while using cinnamon, some physicians recommend avoiding other supplements on the list such as fenugreek, garlic, bitter melon, Continue reading

Stem Cells May Functionally Cure Type 1 Diabetes

Credit: Pixabay
Living with type 1 diabetes can be really rough. There’s a lot of injections and that you have to keep up with and even then, heart health, cardiovascular, and brain health can take some big hits. Some choose to use an insulin pump, but even that has its issues. The disorder affects the immune system, causing it to recognize the cells that make insulin and attacks them. One medical device company, Viacyte, is hoping that they’ve got a device that can protect a special crop of stem cells so that they can live inside the body and produce enough insulin to mostly cure the condition.
About the size of a credit-card, the PEC-Direct contain cells that will respond to rises in blood sugar and begin producing their own insulin, just as the body would on its own. The auto-immune issue is still there, but the device can keep the cells alive long enough to be a cure in all but name.
“If it works, we would call it a functional cure,” Viacyte representative, Paul Laikind, told New Scientist. “It’s not truly a cure because we wouldn’t address the autoimmune cause of the disease, but we would be replacing the missing cells.”
PEC-Direct allows blood vessels to grow into the device itself, allowing the body to feed the stem cells. After three months, they will become islet cells — the kind that monitor the body’s blood sugar and produce and release insulin to compensate. A special fabric helps foster that growth, but patients would still need to take steroids or other immunosuppressing drugs to keep their immune systems from wiping out the freshly-hated i Continue reading

Top Ten Facts About Diabetes

Introduction to Diabetes
All of us know at leat one person suffering from diabetes. This sums up the prevalence of diabetes. Apart from being one of the most prevalent diseases in the world, it is a disease that opens up the pandora's box of many complications. No wonder it is a dreaded disease and people who are diabetic end up with other medical issues as well.
Diabetes is a group of diseases with one thing in common - a problem with insulin. The problem could be that your body either doesn't make any insulin, doesn't make enough insulin or doesn't use insulin properly.
How is Insulin formed ?
The pancreas, which is an organ present in the abdominal cavity of the body, secretes this hormone insulin. This hormone is the key to the way your body processes food, as it helps maintain proper sugar levels (glucose) in your blood. Glucose is your body's fuel. Cells use glucose to produce energy to grow and function. Glucose is escorted by insulin through your bloodstream and insulin helps in unlocking cells to allow glucose to enter.
In diabetes, lack of insulin or the resistance of your cells to insulin prevents the right amount of glucose from entering your cells. The unused glucose builds up in your blood, a condition called hyperglycemia.
What are the Types of Diabetes?
The disease occurs in two types:
Type 1 Diabetes :
In this type of diabetes, the pancreas produces little or no insulin
This type of diabetes generally affects 4-7 years olds or 10-14 years olds and requires treatment with insulin
Type 2 Diabetes:
This is the most common type of diabetes, it generally develop Continue reading