
Pre-diabetes goes into remission on higher protein, lower carbohydrate diet (Zone diet balance)
Can pre-diabetes be reversed with diet? This study says it can be
Type 2 diabetes currently affects 29.1 million people in the USA, 8 million do not know teh have it, they are currently undiagnosed.
Pre-diabetes affect 86 million Americans. This refers to having impaired glucose tolerance, which means glucose is not being cleared properly from the bloodstream and blood glucose remains higher than it should be. They do not yet have high enough blood glucose to warrant the diagnosis of diabetes.
Study protocol
Men and women between 20 and 50 whose BMI categorised them as obese (30 to 55 kg/m2)
All had prediabetes
They were randomly assigned to a high protein (18) or a high carbohydrate diet (20)
The study was for 6 months, 6 dropped out of HP group and 8 from HC group, 24 completed the study, 12 in each group
The HP diet was 30% kcals from protein, 40% kcals from CHO, 30% kcals from fat, versus HC diet; 15% kcals from protein, 55% kcals from CHO, 30% kcals from fat.
Subjects diet was calculated for each individual using resting metabolic rate (RMR) and 500 calories per day was subtracted in order to make it a calorically reduced diet to achieve weight loss.
Meals were pre-prepared and daily allowance was given as 3 meals and 2 snacks.
All subjects were not very active and stayed mainly inactive during the 6 months
Food
Diets were designed so that all nutrients were covered, and they met all the recommended daily intake (RDI) goals for vitamins and minerals.
Dietary fat was primarily monounsaturated and polyunsaturated, plant oils, nuts and semi-liquid margarine.
Carbohydrate
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