Postmenopausal Night Sweats Tied To Diabetes Risk

Postmenopausal Night Sweats Tied to Diabetes Risk

Postmenopausal Night Sweats Tied to Diabetes Risk

Postmenopausal Night Sweats Tied to Diabetes Risk
Women who have postmenopausal vasomotor symptoms (VMS), especially night sweats, have a higher risk for type 2 diabetes, according to a study published December 6 in Menopause. Further, the excess risk increased with the severity and duration of women's symptoms, the researchers found.
"The most plausible and consistent explanation may be through associations with sleep disturbance," write Kristen E. Gray, PhD, from the Veterans Affairs Puget Sound Health Care System and the University of Washington School of Public Health in Seattle, and colleagues. "VMS overall are associated with objective and subjective sleep disturbance, and individuals with disruptions in both the quantity and quality of sleep have a higher risk of diabetes."
Sleep, then, may mediate associations between VMS and diabetes, they add.
"In particular, night sweats are more strongly associated with sleep disturbance than hot flashes, as they occur during the night, which may explain their more pronounced relationship with diabetes," the authors write. "Our results also suggest that night sweats or their effects may be largely responsible for the association between VMS overall and diabetes."
The researchers prospectively tracked and analyzed data for 150,007 postmenopausal women participating in the Women's Health Initiative study to explore possible associations between incident diabetes and VMS from 1993 to 2014. In addition to looking at the severity of hot flashes and night sweats, the researchers looked at the timing of symptoms and how long the Continue reading

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Age At Menopause and Type 2 Diabetes Risk

Age At Menopause and Type 2 Diabetes Risk

Home / Conditions / Type 2 Diabetes / Age At Menopause and Type 2 Diabetes Risk
Age At Menopause and Type 2 Diabetes Risk
Early onset menopause linked to increased risk of type 2 diabetes in a cohort study.
Menopause is a universal phenomenon that all women will eventually experience after a certain age. This major life transition is due to the ovaries cessation of estrogen and progesterone production. The age at which menopause occurs varies greatly from woman to woman, however the age of final menstruation is key to predicting health outcomes. Later age of natural menopause is associated with reduced morbidity and mortality, reduced risk of cardiovascular disease and complications, reduced risk of osteoporosis and fracture and overall better quality of life. The average age of menopause in the United States is 51 years old, with premature menopause being defined by final menstruation before the age of 40. Menopause is associated with weight gain, impaired glucose homeostasis, and an increase in visceral fat; all major risk factors for the development of type 2 diabetes.
Type 2 diabetes is a major risk factor for cardiovascular disease, however, it is unclear if menopause is associated with the risk of developing type 2 diabetes. Animal studies have shown that estradiol decreases the amount of adipose tissues and has a protective role in the metabolism of glucose. Other trials have also shown that postmenopausal women on oral estrogen therapy have a decreased risk of developing type 2 diabetes. Therefore, the aim of this study was to investigate the association betwe Continue reading

Bart Roep, Ph.D., Has Type 1 Diabetes Cure in His Sights

Bart Roep, Ph.D., Has Type 1 Diabetes Cure in His Sights

Bart Roep, Ph.D., Has Type 1 Diabetes Cure in His Sights
Bart O. Roep, Ph.D., has dedicated his life to the search for a cure for type 1 diabetes. And he thinks he is on the brink.
Roep, an internationally renowned immunologist who joined City of Hope last year from the Netherlands Leiden University Medical Center, was recently named the Chan Soon-Shiong Shapiro Distinguished Chair in Diabetes. He believes that this endowment and a $50 million funding project led by the Wanek family will be key in stopping the disease.
We need to do something in addition to treating the symptoms, Roep said. Diabetes has surpassed cancer as a cause of death. One of the goals of the diabetes program at City of Hope is to accelerate the progress against the disease. And the new $50-million grant is a catalyst to get there faster.
Instead of dealing with the effects of the disease, Roep is committed to treating the disease itself.
For 100 years, weve known how to deal with the symptoms, he said. Now, for the first time, we can tackle the cause. This is really one of the most exciting times since the discovery of insulin. We have the opportunity to offer a completely new generation of therapy to these patients.
After studying the mechanism of type 1 diabetes for the last two decades, Roep, the founding chair of the DepartmentofDiabetesImmunology within the Diabetes&MetabolismResearchInstituteatCityofHope , recently had his Eureka! moment when he realized that the disorder varies greatly from patient to patient.
One of the new insights is that diabetes is very diverse, he said. Based on Continue reading

Kidney Cancer and Diabetes

Kidney Cancer and Diabetes

Is There a Link Between Kidney Cancer and Diabetes?
Evidence linking diabetes and kidney cancer has grown stronger over the past decade, leading researchers to investigate the reasons behind these links.
Kidney cancer is a disease in which kidney cells become cancerous and grow into a tumor.
Most kidney cancers are found before they spread to distant organs. Caught early , they can usually be treated successfully. Tumors can grow large if not detected.
This year, the American Cancer Society reports there will be at least 64,000 new cases of kidney cancer, affecting mostly men. Up to 15,000 people could die this year from this type of cancer.
Diabetes is a group of diseases resulting in high blood glucose (too much sugar in the blood). As of 2014, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 29.1 million people, or 9.3 percent of the U.S. population, have diabetes both diagnosed and undiagnosed.
Type 1 and type 2 diabetes are the two most common forms of diabetes, but there are other kinds, including one which occurs during pregnancy. Up to 95 percent of diabetics have type 2, according to NIDDK.
You are more likely to have type 2 if you are 45 or older, have a family history of diabetes, or are overweight and inactive. Other health problems, such as high blood pressure, also contribute to the development of type 2 diabetes.
Diabetes is just one of the many risk factors for kidney cancer. Obesity, smoking, high blood pressure, and family history are also potential risk factors, among others.
How diabetes is linked to kidney Continue reading

Deborah Greenwood discusses technology enabled diabetes self-management solutions

Deborah Greenwood discusses technology enabled diabetes self-management solutions

Deborah Greenwood discusses technology enabled diabetes self-management solutions
Posted on Jul 13, 2017 by Barbara Eichorst
Technologyis now part of a newscience within diabetes care. As diabetes educators, we are partnering with people with diabetes (PWD) to support their efforts in using the digital interventions. I am very excited about the first systematicreview of systemic reviews evaluating the existing evidence and best practicewhile using technology in diabetes care and education.Deborah Greenwood,PhD, RN, BC-ADM, CDE, FAADE Chief Digital Research Officer-Diabetes Mytonomy,is one of the authors of "A Systematic Review of Reviews Evaluating Technology-Enabled Diabetes Self-Management Education and Support" that was published recently. This month, I am happy to share my conversation with Deborah about diabetes and technology.
Deborah, how and why doyouhave an interestin technology as a CDE?
In my doctoral program, I focused all my elective courses in informatics and my independent study/internship opportunities in telehealth and diabetes. For my dissertation study, I conducted a randomized clinical trial using paired glucose checking in people with type 2 diabetes not on insulin supported by a technology-enabled remote monitoring system. The intervention group lowered A1C significantly more than the control group at 6 months. The study incorporated a complete feedback loop where PWD followed structured monitoring principles, shared their data with CDEs, were provided with feedback through the electronic health record and made behavior and medication changes. I Continue reading

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