Paleo vs. Alzheimer’s & Type 3 Diabetes
Dave loved his job as a financial analyst. He was 66 years old when he left work one day and couldn’t figure out how to get home. In the following months, his work performance declined to the point where he was asked to retire. He became more confused, felt chronically fatigued, and even the simplest tasks became very complicated. Eventually, his eyesight declined, his speech became unintelligible, and he stopped recognizing those nearest and dearest to him. Dave’s daughter had to quit her job to take care of him and now they live together in the unforgiving world of Alzheimer’s.
What is Alzheimer’s?
Sixty to eighty percent of dementia cases are Alzheimer’s, a disease characterized by the emergence of beta-amyloid plaques and tangles called Tau in the hippocampus region of the brain that controls memory. Beta-amyloid builds up between nerve cells and inhibits signaling while Tau forms inside cells and disrupts transport systems for nutrients and other essential compounds.
As beta-amyloid and Tau spread to other neural regions, affected cells die and cognition and biological functions worsen. Originally, it was thought that beta-amyloid or Tau drove the disease. Newer theories focus on genetic and epigenetic drivers as well as inflammatory processes, metabolic dysfunctions and even infections as mechanisms. Although nobody knows the actual cause(s), Alzheimer’s is increasingly thought to be the result of a combination of genetic, environmental, and lifestyle factors. (1)
The Reach of Alzheimer’s
Alzheimer’s affects 5.4 million Americans with 5.2 million of th Continue reading