New Study Links Wheat To Weight Gain and Diabetes
A new animal study published in the journal PLoS sheds light on a possible mechanism behind the weight- and diabetes-promoting properties of wheat observed in humans, and perhaps offers some vindication for Dr. William Davis' New York Times best-selling but heavily criticized book 'Wheat Belly,' wherein the argument is made that wheat is a major contributing factor to the epidemic of obesity and diabetes presently afflicting wealthier, gluten-grain consuming nations.
In the new study, researchers from The Bartholin Institute, Copenhagen, Denmark, explored the role that gliadin, a difficult to digest class of proteins within wheat, plays in promoting weight gain and insulin secretion in both animal and cell models, finding that gliadin-treated mice gained 20% more weight (by day 100) than gliadin-free controls, and that gliadin fragments induce insulin secretion in pancreatic beta cells, the cells responsible for producing insulin, and which in type 1 diabetes are destroyed or rendered dysfunctional.
Gliadin does not break down easily in the body because they are extremely hydrophobic ("water fearing"), and contain disulfide bonds (the same kind found in human hair and vulcanized rubber); as a result, undigested wheat gliadin fragments can enter through the intestinal wall, gaining systemic access to the human body. This can result in inflammatory and autoimmune conditions, among many other possible negative health effects (note: we have documented over 200 adverse health effects associated with wheat exposure).
Gliadin fragments have even been found in mother's milk, ind Continue reading