
Meta-analysis of RCTs suggests vitamin D supplementation improves markers of type II diabetes
Meta-analysis of RCTs suggests vitamin D supplementation improves markers of type II diabetes
Posted on: October 13, 2017 by Riley Peterson & John Cannell, MD.
A recent meta-analysis of randomized controlled trials discovered that vitamin D supplementation helped control glycemic response and improved insulin sensitivity in individuals with type II diabetes.
Type II diabetes has become an increasing health concern over recent years, as overweight and obesity rates have skyrocketed. Furthermore, approximately 57% of healthcare expenditures are due to diabetes and related events in North America each year.
Diabetes is considered to be a major risk factor for many adverse health conditions and diseases. According to the available research, type II diabetes contributes to:
70% of non-traumatic lower limb amputations
While poor diet, lack of exercise and genetics are the main risk factors for developing type II diabetes, evidence also suggests that vitamin D levels plays a role in the metabolic status of type II diabetes patients. Research indicates that vitamin D deficiency is associated with abnormal glucose metabolism, decreased insulin sensitivity and overall risk of developing type II diabetes. However, some of the available evidence on the effect of vitamin D supplementation on glycemic control in those with type II diabetes is conflicting. Therefore, researchers from this meta-analysis decided to explore this relationship.
A total of 23 RCTs and 1,477 individuals were included in this analysis. Studies were included if they were randomized controlled trials, an
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