London trial to aggressively treat diabetes expanding
Aggressive treatment for Londoners with Type 2 diabetes has proven so popular, Lawson Health Research Institute will open up enrolment in a study for a third time since 2015.
Doctors usually start treating diabetics with a single medication, and only add other drugs and insulin if the disease worsens. That wait-and-see approach has been turned on its head in a study in which doctors treat patients aggressively from the start with two diabetes medications plus insulin at bedtime for three months.
“The goal of the . . . study is to take a proactive approach to help people early in the disease, normalize their blood sugars for a period of 12 weeks and then slow the progression of the disease and the need for additional medications,” says Dr. Irene Hramiak, Lawson researcher, endocrinologist and chief of the Centre for Diabetes, Endocrinology and Metabolism at St. Joseph’s Health Care London.
“We want to know if we can induce remission, for how long and whether it matters what combination of medications we use.”
Lawson is one of seven Canadian sites taking part in the REMIT study, led by the Population Health Research Institute, a joint institute of McMaster University and Hamilton Health Sciences. A preliminary study produced remission in up to 40 per cent of patients for at least three months.
With a family history of Type 2 diabetes, Greg Ackland was diagnosed more than six years ago when he underwent an operation for a hernia. He developed a mild infection and, while being treated, his care team discovered his blood sugar levels were high.
Ackland started treatmen Continue reading