Just Read: Alzheimers Disease Is Type 3 DiabetesEvidence Reviewed
Ted Eytan, MD ( @tedeytan ) December 29, 2017
At Low Carb San Diego, I first heard the term Type III Diabetes, which, it turns out is new to the 21st Century, but not to this decade, as this paper was published in 2008 and references use of the term as early as 2005. The term is intriguing and opens the mind to a potential mechanism for dementia progression, and maybe prevention.
The dementia review, which appears very complete (and with a very respected team of experts, some of whom I have the pleasure to know), covers the determinants of dementia using the best data available.
It also introduces (to me) the concept of cognitive reserve, because it has been shown that people who do not have dementia while they are alive have damaged brains when they are examined in death.
Interestingly to me, this single concept is similar to insulin resistance, because its known that a person can have normal glucose control (or glucose control reserve) at the same time their insulin system is struggling.
In the review, diet/nutrition approaches for prevention treatment are briefly discussed, as well as the potential relationship to insulin resistance in the brain, but Diabetes Type III is not mentioned specifically & this paper isnt referenced.
With that in mind, and after asking Georgia and the study author on Twitter for comment on this, I decided to review this paper, written by a team at Brown University, to get grounded:
Cognitive impairment is associated with disorders in brain glucose metabolism
People with diabetes or related metabolic syndromes are at much higher risk Continue reading