
Is Glaucoma a Neurodegeneration caused by Central Insulin Resistance: Diabetes Type 4?
Is Glaucoma a Neurodegeneration caused by Central Insulin Resistance: Diabetes Type 4?
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Jaypee Brothers Medical Publishing (P) Ltd.
Is Glaucoma a Neurodegeneration caused by Central Insulin Resistance: Diabetes Type 4?
How to cite this article: Dada T. Is Glaucoma a Neurodegeneration caused by Central Insulin Resistance: Diabetes Type 4? J Curr Glaucoma Pract 2017;11(3):77-79.
Glaucoma is an acquired multifactorial progressive neurodegenerative syndrome with complex pathogenesis. It is characterized by accelerated retinal ganglion cell (RGC) apoptosis and leads to optic neuropathy with visual field defects, the intraocular pressure (IOP) being a major risk factor. The only therapy currently available is lowering of IOP with medical/laser/surgical therapy; however, many patients continue to progress despite an adequately controlled or apparently normal IOP. Recent studies have shown that glaucoma patients have central neurodegenera-tion involving both the occipital cortex and lateral genicu-late body (LGB). 1 , 2 It has been postulated that glaucoma may be a disease initially affecting the central nervous system (CNS) and traveling dow
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