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India Is The Diabetes Capital Of The World!

India is the diabetes capital of the world!

India is the diabetes capital of the world!

The diabetes capital of the world with as many as 50 million people suffering from type-2 diabetes, India has a challenge to face. However, medical experts feel that timely detection and right management can go a long way in helping patients lead a normal life. Diabetes might be one of the most talked about diseases across the world and especially in India, but awareness about the same can well be estimated by the fact that India today has more people with type-2 diabetes (more than 50 million) than any other nation.
With the country having the highest number of diabetic patients in the world, the sugar disease is posing an enormous health problem to our country today. Often known as the diabetes capital of the world, India has been witnessing an alarming rise in incidence of diabetes according to the International Journal of Diabetes in Developing Countries. According to a World Health Organization (WHO) fact sheet on diabetes, an estimated 3.4 million deaths are caused due to high blood sugar.
The WHO also estimates that 80 per cent of diabetes deaths occur in low and middle-income countries and projects that such deaths will double between 2016 and 2030. It has been further estimated that the global burden of type-2 diabetes is expected to increase to 438 million by 2030 from 285 million people (recorded in 2010). Similarly, for India this increase is estimated to be 58%, from 51 million people in 2010 to 87 million in 2030. But debates, discussions and deliberations aside, the fundamental thing is to know what exactly is diabetes.
To put it simply, it is a medical condi Continue reading

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What's Your Type? With Diabetes, It Can Be Unclear

What's Your Type? With Diabetes, It Can Be Unclear

A drop in the number of newly-diagnosed diabetes cases is good public health news. But for the Type 1 diabetes community it's a source of frustration, because the numbers hide their story.
Last month, the Centers for Disease Control and Prevention announced that new cases of diagnosed diabetes among adults in the U.S. had finally dropped after decades of growth, from 1.7 million in 2008 to 1.4 million in 2014.
The decline in new cases gives "confidence that our diabetes prevention efforts are working and we are moving in the right direction," CDC officials said via email to Shots. "We know that long-term lifestyle changes in those at high risk are critical to prevent Type 2 diabetes and maintain this progress."
While it's certainly the right direction for the more common Type 2 diabetes, the findings don't apply to Type 1, a different condition that appears to be on the rise and that is not caused by obesity or lifestyle factors. Rather, Type 1 diabetes results from an autoimmune destruction of the insulin-producing cells of the pancreas.
And while Type 2 diabetes is linked to obesity and can typically be managed with diet, physical activity, and various medications including insulin for some, Type 1 always requires insulin treatment, either with multiple daily injections or an infusion pump, and is far more labor-intensive to manage.
Type 1 is believed to make up roughly 5 percent of the total 29 million adults and children in the U.S. who currently live with diabetes, or about 1.5 million people. But, the actual number isn't really known, and some surveys have suggested t Continue reading

Diabetes in your DNA? Scientists zero in on the genetic signature of risk

Diabetes in your DNA? Scientists zero in on the genetic signature of risk

Many different mutations linked to Type 2 diabetes all occur in key stretches of active DNA within pancreatic islet cells, interfering with the activity of a master regulator.
Why do some people get Type 2 diabetes, while others who live the same lifestyle never do?
For decades, scientists have tried to solve this mystery – and have found more than 80 tiny DNA differences that seem to raise the risk of the disease in some people, or protect others from the damagingly high levels of blood sugar that are its hallmark.
Disruption of regulatory grammar plays a significant role in the genetic risk of Type 2 diabetes.
But no single “Type 2 diabetes signature” has emerged from this search.
Now, a team of scientists has reported a discovery that might explain how multiple genetic flaws can lead to the same disease.
They’ve identified something that some of those diabetes-linked genetic defects have in common: they seem to change the way certain cells in the pancreas “read” their genes.
The discovery could eventually help lead to more personalized treatments for diabetes. But for now, it’s the first demonstration that many Type 2 diabetes-linked DNA changes have to do with the same DNA-reading molecule. Called Regulatory Factor X, or RFX, it’s a master regulator for a number of genes.
The team reporting the findings in a new paper in the Proceedings of the National Academy of Sciences comes from The Jackson Laboratory for Genomic Medicine, the University of Michigan (U-M), National Institutes of Health, University of North Carolina, and the University of Southern Cal Continue reading

Diabetes and Eye Health

Diabetes and Eye Health

Diabetes is a disease that affects the body’s ability to produce or use insulin effectively to control blood sugar (glucose) levels. Although glucose is an important source of energy for the body’s cells, too much glucose in the blood for a long time can cause damage in many parts of the body, including the heart, kidneys, blood vessels and the small blood vessels in the eyes.
When the blood vessels in the eye’s retina (the light sensitive tissue lining the back of the eye) swell, leak or close off completely — or if abnormal new blood vessels grow on the surface of the retina — it is called diabetic retinopathy.
People who are at greater risk of developing diabetic retinopathy are those who have diabetes or poor blood sugar control, women who are pregnant, and people with high blood pressure, high blood lipids or both. Risk also increases with duration of diabetes. For example, one woman developed diabetic retinopathy after living with diabetes for 25 years. Also, people who are from certain ethnic groups, such as African-Americans, Hispanics and Native Americans, are more likely to develop diabetic retinopathy. In fact, a new study confirms that diabetes is a top risk factor for vision loss among Hispanics.
According to the Centers for Disease Control and Prevention (CDC), about 90 percent of diabetes-related vision loss can be prevented, but early detection is key. People with diabetes should get critical, annual eye exams even before they have signs of vision loss. However, studies show that sixty percent of diabetics are not getting the exams their doctors re Continue reading

How to Avoid High Morning Blood Sugars

How to Avoid High Morning Blood Sugars

We’ve all been there before.
You wake up. Lay in bed for a few before getting your booty up to go kill the workday and accomplish big things. Check your blood sugar. 115 (6.3 mmol/l) stares back at you.
You smile to yourself: life is good.
Forty minutes later, when you sit down to eat, your CGM gives you a “high” notification, and you’re 180. You have eaten NOTHING. All you’ve done is prepare for the day and prepare food. Now you face the grim potential of chasing your sugars all day long.
What the…
This isn’t Dawn Phenomenon
Many people would blame this rise in blood sugar on dawn phenomenon (DP), which has a similar endpoint, but a different mechanism. Dawn phenomenon is the result of hormones releasing in the body in the early morning – predominantly growth hormone, cortisol, epinephrine, and glucagon – which in turn increase insulin resistance. The current basal insulin from the pump or long-acting injections is no longer enough, and blood sugars rise.
That hormonal surge happens around 2am-6am, with most of it occurring in the middle of the night. Let’s say you woke up at 8:30am and aren’t in the “DP zone.” It’s not DP. Then what?
Feet on the floor
The moment your feet touch the floor as you roll out of bed, you signal to your body, “Hey, I need energy for all the stuff I’m about to do!” Your body recognizes you haven’t eaten in lord knows how many hours. Your body is also lazy smart and wants the most easily accessible source of energy: the liver.
The liver is the Wal-Mart for stored energy, since it’s got everything you need. It Continue reading

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