
Fasting diet could regenerate pancreas and reverse diabetes, researchers say
A fasting diet has the ability to regenerate the pancreas and could potentially reverse diabetes, researchers have found.
A US study, published in scientific journal Cell, tested a modified version of the fasting-mimicking diet (FMD) on both mice and human cells.
The findings showed cycles of the diet could regenerate pancreatic cells to restore insulin in type 1 diabetes patients and could also reverse both type 1 and 2 diabetes in mice.
The study's co-author, Dr Valter Longo from the University of Southern California, told the ABC the findings were "potentially very exciting" because they could lead to cures for both type 1 and type 2 diabetes.
Type 1 diabetes, unlike type 2, is an autoimmune condition for which there is no known cause or cure. In patients with type 1 diabetes, the pancreas stops producing insulin.
Dr Longo also said a FMD could also regenerate other organs because their research had shown similar effects for blood cells.
"They show that extreme diets with very specific compositions can trigger self repair and regeneration processes in the mouse and possibly humans," Dr Longo said.
Taking into account the challenges and side-effects of fasting in humans, Dr Longo and his team developed a modified low-calorie, low-protein and low-carbohydrate but high-fat four-day FMD.
The diet caused changes in the levels of specific growth factors, glucose, and ketone bodies and reduced the blood glucose on pre-diabetic patients.
Mice receiving the FMD showed improved glucose tolerance and insulin tolerance.
The pancreas helps to control blood sugar levels and restoring
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