FAIL: Diabetes Medication Isn't Working. So What Does?
9.3% of Americans and 6.5% of Canadians suffer from diabetes. There is a lot of agreement about the medical treatment. But does the treatment work? At least 5 crucial studies have found that it doesn’t.
People with type 2 diabetes are 2-4 times more likely to die from heart disease. But when the authoritative Cochrane group did a systematic review of 20 studies of type 2 diabetics, they found that there was no significant benefit to intensely targeting blood sugar control with drugs for either cardiovascular death or death from any cause. While it did reduce the risk of amputation, retinopathy and nephropathy, it also increased the risk of hypoglycaemia by 30% (Cochrane Database Syst Rev 2011 Jun 15;(6):CD008143).
The same year, a meta-analysis of 13 controlled studies confirmed that there was no significant benefit of drug treatment for cardiovascular death or death from any cause. While at first it looked like drugs may reduce the risk of nonfatal heart attacks, when only the high quality studies were included, that apparent benefit disappeared; however, what now appeared was a 47% increase in the risk of congestive heart failure. So, diabetes drugs did not reduce the risk of death from heart disease, they increased them. They also doubled the risk of severe hypoglycaemia (BMJ 2011 Jul 26;343:d4169).
A third systematic review and meta-analysis included 14 studies of type 2 diabetics. Its negative findings went even further. Not only did diabetes meds confer no benefit for fatal or nonfatal heart attack or stroke nor for death from any cause, this study also found insuff Continue reading