Difference between Diabetes Mellitus and Diabetes Insipidus
Diabetes Mellitus It is characterized by hyperglycemia (high blood sugar level), glycosuria (glucose in urine), polyuria ( increased volume of urine due to the osmotic effect of glucose), polydipsia (excessivie thirst), polyphagia (excessive appetite). It is due to the hyposecretion of insulin or lack of insulin.
It is of two types:- Diabetes Type I and Diabetes Type II.
Diabetes Type I (Insulin Dependent Diabetes Mellitus, IDDM): It is cased due to deficient insulin production by pancreas because either beta cells of islets of Langerhans are not able to produce insulin or beta cells are absent.
Diabetes Type II (Insulin Independent or Non insulin Dependent Diabetes Mellitus, NIDDM): It is an inherited recessive autosomal disorder appearing after the age of 40 years in which the cells fail to take up insulin from blood. It results in deficient passage of glucose form blood into the cell surfaces for storage or for direct consumption. It may occur due to defective insulin receptors over cell surfaces or abnormality on plasma protein amylin. The phenomenon is called insulin resistance. This type of diabetes mellitus accounts for 80-90% of all cases of diabetes.
It is kept under control by administration of insulin in case of insulin dependent diabetes. and hypoglycaemics in case of insulin independent diabetes. Sugar free diet is a pre requisite in both the cases.
Diabetes Insipidus (Drinker’s disease): Hypo secretion of ADH (Antidiuretic hormone or Vasopressin) causes a disorder known as diabetes insipidus (Excretion of large quantity of dilute urine). ADH is released into Continue reading