Diabetes Remission Possible With Significant Weight Loss: DiRECT
Individuals with type 2 diabetes who lose a significant amount of weight through a strict dietary intervention can send their diabetes into remission, according to the results of a new study.
Nearly half of individuals who adhered to the primary care-led program for weight management no longer had type 2 diabetes at 12 months, with remission rates even higher among those who lost more weight. Among individuals who lost 15 kg or more, for example, 86% had a remission of their diabetes.
“People with type 2 diabetes can get rid of it if they’re serious enough, but they need ongoing support and buy-in from their families if they’re going to keep the weight off and keep diabetes away long-term,” senior investigator Roy Taylor, MD (Newcastle University, Newcastle-upon-Tyne, England), told TCTMD. “The important thing is that physicians can relearn about type 2 diabetes and explain to people that it’s possible for them to get out of it. They don’t need to live with this threat to their eyes, their feet, their nerves.”
In an editorial, Matti Uusitupa, MD (University of Eastern Finland, Kuopio), calls the study findings “impressive,” saying they “strongly support the view that type 2 diabetes is tightly associated with excessive fat mass in the body.” These results, along with other studies of type 2 diabetes prevention, Uusitupa adds, “indicate that weight loss should be the primary goal” of treatment.
Darren McGuire, MD (UT Southwestern Medical Center, Dallas, TX), who was not involved in the study, said the findings were “quite striking,” particular Continue reading