Diabetes: Heart attack risk due to loss of small blood vessels around the heart
People with diabetes have a significantly higher risk for heart attack. Now, new research suggests that diabetes damages the small blood vessels around the heart, and this might explain the link to heart attack. In a study reported in the Journal of the American College of Cardiology, the researchers also propose a solution may lie in gene therapy.
Diabetes is a chronic disease that arises either because the body does not produce enough insulin (typical of type 1 diabetes) or because it cannot effectively use the insulin it produces (typical of type 2 diabetes). Around 90 percent of people with diabetes have type 2.
Insulin is a hormone that helps keep blood sugar (glucose) under control. Uncontrolled diabetes results in high blood sugar, or hyperglycemia, which, over time, damages many parts of the body, including nerves and blood vessels.
The number of people with diabetes worldwide was estimated to be 422 million in 2014, up from 108 million in 1980. The disease is a major cause of blindness, heart attack, stroke, kidney failure, and lower limb amputation
In the United States, there are now more than 29 million people with diabetes, up from 26 million in 2010.
Another 86 million people have prediabetes, a condition in which blood sugar is higher than normal but not yet in the range for type 2 diabetes.
Diabetes affects small cardiac blood vessels
The global prevalence of diabetes among adults rose from 4.7 percent in 1980 to 8.5 percent in 2014.
Once a disease seen only in adults, the number of children with type 2 diabetes is increasing.
The total medical costs and lost Continue reading