
Diabetes drug and aspirin boosts cancer drug effectiveness | Daily Mail Online
Metformin may slow breast cancer growth and reverse treatment resistance
Adding aspirin to a cancer drug could help combat tumors resistant to therapies
These include pancreatic, lung and colorectal cancers, as well as melanomas
A widely-used diabetes drug and over-the-counter aspirin could help boost the effectiveness of cancer treatments, two studies suggest.
Research has found that metformin used to improve the way your body handles insulin may slow breast cancer growth and reverse treatment resistance.
Another study discovered adding aspirin to a cancer drug could make it more powerful in combating a group of tumors that are highly resistant to therapies.
These include some pancreatic, lung and colorectal cancers, as well as a small percentage of melanomas.
Together, the findings offer hope for people with certain difficult-to-treat forms of the disease.
A widely-used diabetes drug and over-the-counter aspirin could help boost the effectiveness of cancer treatments, two studies suggest (stock image)
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Canadian scientists found that metformin, used to treat type 2 diabetes, reduced the rapid reproduction of tumor cells in the laboratory.
It also prevented or delayed resistance to the chemotherapy drug doxorubicin.
Other laboratory experiments and tests on mice showed that metformin reversed protein markers associated with multiple drug resistance (MDR).
This meant the drug might help resistant breast cancers to start responding to treatment again, said the researchers.
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