Diabetes could be cured as scientists find cause of disease
Diabetes could be cured after scientists discovered that toxic clumps of a hormone stop cells producing insulin.
Scientists at Manchester University have found that both Type 1 and Type 2 diabetes are driven by the same underlying mechanism.
The findings suggest that both forms occur when the hormone amylin begins to clump together, surrounding cells, and preventing them from producing insulin.
Insulin is essential for moving sugar from the blood stream into muscles and fatty tissue to provide energy. But too little insulin allows dangerous levels of glucose to build up in the blood, causing damage to the heart kidneys, eyes and nerves.
However the new finding could pave the way for drugs which stop the amylin build-up in the first place or dissolve clumps which are already present.
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More than three million people in Britain have been diagnosed with diabetes, with that figure expected to five million by 2025.
The vast majority of sufferers (85 per cent) have Type 2 diabetes, which is linked to obesity, poor diet and sedentary lifestyles.
More than 70,000 deaths a year occur among those suffering from the condition - one in seven of all deaths.
The pancreas produces both insulin and amylin Continue reading