diabetestalk.net

Defective, Infectious Proteins Linked To Type 2 Diabetes

Defective, Infectious Proteins Linked to Type 2 Diabetes

Defective, Infectious Proteins Linked to Type 2 Diabetes

More than one in ten people in the US have type 2 diabetes — that's over 29 million people. It's characterized by excessive sugar (glucose) in the blood due to the development of resistance to insulin, the hormone that normally metabolizes glucose.
Deposits of folded and clumped proteins in the pancreas are also common in type 2 diabetes. There, they may impact the ability of the pancreas to function properly. But, researchers from McGovern Medical School at the University of Texas Health Science Center have discovered that they could play a role in causing the disease.
The configuration of protein, including how it's folded, is one factor that contributes to its ability to function properly. The scientists found the abnormally folded protein that accumulates in diabetes can induce the symptoms of the disease. What's more, the protein is similar to an infectious protein found in diseases like Creutzfeldt-Jakob disease, Kuru, and Bovine Spongiform Encephalopathy (mad cow disease).
Don't Miss: New Study Unveils the True Story of Kuru, a Fatal Brain Disease Spread by the Cultural Practice of Eating the Dead
Study researcher Claudio Soto and colleagues published their findings on August 1, in The Journal of Experimental Medicine.
Type 2 Diabetes
Symptoms of type 2 diabetes include frequent infections, hunger, fatigue, increased thirst and urination, and blurry vision, but some people have no symptoms for the first several years they have the disease. Lab tests to measure blood glucose, or A1C, a test that measures the glucose average over the last three months, can confirm th Continue reading

Rate this article
Total 1 ratings
What is Type 2 Diabetes? Its Causes, Symptoms, Treatment & Diet

What is Type 2 Diabetes? Its Causes, Symptoms, Treatment & Diet

A tough life-long disease, Diabetes is something that affects the body’s functioning. It affects body’s glucose and blood sugar levels. Although diabetes has different types, the primarily seen ones are Type 1, Type 2 and Gestational.
We here would be looking into the Type 2 Diabetes in brief and shall seek answers for the same. Join in as we dig deep into ‘Type 2 Diabetes and its Causes, Symptoms, Treatment and Diet’.
Let’s start off then.
What is Type 2 Diabetes?
On a general note, our body’s pancreas is stimulated to produce insulin for the body. The insulin helps change the glucose obtained from the food into energy for the body. However, in the Type 2 Diabetes, the pancreas still produces the insulin but the body doesn’t use it as required upon. Also known by as insulin resistance, Type 2 diabetes is seen commonly among the diabetic patients, the stats revealing at 85% of all diabetic patients.
The Root Cause of Type 2 Diabetes
Type 2 Diabetes is caused as a result of combination of different things like DNA, obesity, metabolic syndrome, broken beta cells and more. More so over, childhood obesity is one of the grave reasons for diabetes later in the adult age.
The disease is also seen in people with high blood pressure, high level of cholesterol, extra fat layers around the body and waist. For many, the high glucose production from liver also affects the way diabetes is contracted upon.
The Risk Factors for Type 2 Diabetes
There are different risk factors associated with Type 2 Diabetes. A few major things that affect highly in Type 2 Diabetes are-
Gene F Continue reading

How to Lower Your A1C Levels: More Steps You Can Take

How to Lower Your A1C Levels: More Steps You Can Take

You may be familiar with the “ABCs” of diabetes: A1C, blood pressure, and cholesterol. This acronym is part of a larger diabetes campaign called “Know Your Numbers,” and hopefully you’re aware of all of your numbers — what they are, what they should be, and how often to get them checked. Obviously, knowing your A1C and knowing what you can do if it’s not at goal is a big part of diabetes management.
The focus last week and this week has been on all things A1C: what it is, what the general goal is, why it matters, and ways to get it to where it needs to be.
What else does it take to lower your A1C?
Figuring out how to lower your A1C to whatever your personal goal is can sometimes seem like solving a puzzle. You try something and it may or may not help, or it helps but not enough. Then you try something else. Yes, it can be frustrating, but eventually you’ll hit on a strategy that works for you. Last week, we looked at how a healthy eating plan (including keeping carbs consistent and sticking to an eating schedule) and a physical activity program can help. Research shows that an eating plan can lower A1C levels by 1–2%; physical activity can lower A1C by 0.6–1%, according to various studies. But what if these two strategies aren’t enough? Then what?
Time for medication?
Diabetes medicines generally lower A1C levels anywhere from 0.5% to as much as 3.5%. The A1C-lowering effect of medicines can vary from person to person, however, and the effect is often dependent upon how high the A1C is to begin with.
Insulin. We know that people who have Type 1 diabete Continue reading

Diabetes Glossary

Diabetes Glossary

Antibodies
Antibodies are specialized proteins that are part of the immune system. They are created when an antigen (such as a virus or bacteria) is detected in the body. The antibodies bond with the specific antigen that triggered their production, and that action neutralizes the antigen, which is a threat to the body. Antibodies are created to fight off whatever has invaded the body. See also autoantibodies.
Antigens
An antigen is a foreign substance (such as a virus or bacteria) that invades the body. When the body detects it, it produces specific antibodies to fight off the antigen.
Autoantibodies
Autoantibodies are a group of antibodies that “go bad” and mistakenly attack and damage the body’s tissues and organs. In the case of type 1 diabetes, autoantibodies attack the insulin producing beta cells in the pancreas.
Autoimmune disorder
If you have an autoimmune disorder (also called an autoimmune disease), your body’s immune system turns against itself and starts to attack its own tissues.
Basal secretion (basal insulin)
We all should have a small amount of insulin that’s constantly present in the blood; that is the basal secretion. People with type 1 diabetes must take a form of insulin that replicates the basal secretion throughout the day; that’s basal insulin.
Beta cells
Beta cells are located in the islets of Langerhans in the pancreas. They are responsible for making insulin.
Blood glucose level
The blood glucose level is how much glucose is in your blood at a given time. This level is very important for people with diabetes, and they must monitor thei Continue reading

Diabetes: a lost childhood

Diabetes: a lost childhood

On the day five years ago when my daughter Izzi, then aged 10, was diagnosed with type 1 diabetes, her seven-year-old brother Rowan was reluctant to visit her in the hospital. "Is she going to die?" he asked gravely. It was hard to reassure him through my tears, as I had only the vaguest idea of what type 1 diabetes was. I now know that, without insulin, which she will need to inject multiple times every day for the rest of her life, the answer would almost certainly have been yes.
Type 1 diabetes is an autoimmune condition in which insulin-producing cells in the pancreas just give up. No one knows why, and there is no cure. Izzi did nothing to cause this to happen and we have no family history of the condition, so, for us, there is no genetic link. She was just unlucky, like the 400,000 other people in the UK who have it. The condition is a life sentence: every organ in her body is under constant attack and the only defence is to pump herself full of insulin.
We only realised something was wrong when Izzi started to drink large quantities of water. At first I was pleased: I had always thought she didn't drink enough. But when one day she forgot to take her water bottle to school and went into a massive panic, I began to suspect there was a problem. We later learned that the need to drink lots was a result of her body's attempt to flush out the excess sugar in her blood. Insulin is the hormone that acts as a key to unlock pathways between the blood and the body's cells, which need the sugar for energy. Without insulin, the concentration of sugar in the blood can build up to Continue reading

No more pages to load

Popular Articles

  • Drinking Wine Is Linked to a Lower Risk of Diabetes

    TIME Health For more, visit TIME Health. Drinking alcohol—especially wine—every few days may help protect against type 2 diabetes, suggests a new study published in the journal Diabetologia. People in the study who drank three to four days a week were about 30% less likely to develop diabetes than those who drank less than once a week. This isn’t the first study to find a link between drinki ...

  • Cholesterol-Lowering Drugs May Be Linked to Diabetes

    You may have concerns about taking a cholesterol-lowering statin drug, such as atorvastatin (Lipitor and generic), rosuvastatin (Crestor), and simvastatin (Zocor and generic), after a recent study linked those drugs to an increased risk of type 2 diabetes. But Consumer Reports Best Buy Drugs experts say the heart-protective benefit of statins usually outweighs the risk of diabetes, so don’t skip ...

  • Diabetes and obesity linked to number of nearby fast-food outlets, study finds

    Diabetes and obesity rates in inner cities can be linked to the number of fast-food outlets near people’s homes, a study has found. Scientists based their conclusion on a study of 10,000 people in the UK. They found there were twice as many fast-food outlets within 500 metres of homes in non-white and socially deprived neighbourhoods. The lead researcher, Prof Kamlesh Khunti from the University ...

  • Drinking moderately linked to lower diabetes risk

    Drinking three to four times a week has been linked to a lower risk of type 2 diabetes than never drinking, Danish researchers suggest. Wine appears to be particularly beneficial, probably as it plays a role in helping to manage blood sugar, the study, published in Diabetologia, says. They surveyed more than 70,000 people on their alcohol intake - how much and how often they drank. But experts sai ...

  • BREAKING: Diabetes Drugs Linked to Alzheimers and Dementia

    If you’re diabetic and you’re taking medication, you’re probably putting your brain at great risk. Their calling the new study from the Albert Einstein College of Medicine a “Diabetes Game-Changer." It proves that prolonged use of diabetes drugs puts you at risk for a deficiency which can cause neurological problems, including dementia, and even brain shrinkage. This study used data that w ...

  • Imbalance Of Gut Bacteria Linked To Elevated Risk For Diabetes

    New data from researchers at the University of Copenhagen provides stronger evidence linking certain bacteria that populate our intestinal tract with a higher risk for developing insulin resistance, ultimately a precursor to developing diabetes. The research was published in the journal Nature late last week, suggesting that the gut microbiome might be a potential target for therapeutic interventi ...

  • Gluten-free diets are not actually linked to diabetes

    In the pantheon of fad diets, there is perhaps none more hated on than gluten-free. And despite how annoying fad dieters are (if I hear one more person order a salad because they’re ‘gluten-free’ and then ask for croutons…), it’s not unreasonable to want to avoid foods that might possibly be bad for you. But is gluten actually bad for people who don’t have a problem with it? There’s ...

  • Poor Diet Linked to Half of Heart Disease, Stroke, Diabetes Deaths

    Most of us are aware that what we eat affects our health. But the results of a new study illustrates that fact vividly: Almost half of deaths in one year caused by heart disease, stroke and type 2 diabetes in a large group of Americans were linked with a poor diet. Researchers from Tufts University in Boston, the University of Cambridge in England and Montifiore Medical Center in New York analyzed ...

  • Diabetes and heart disease linked by genes, reveals Penn-led study

    PHILADELPHIA -- Type 2 diabetes (T2D) has become a global epidemic affecting more than 380 million people worldwide; yet there are knowledge gaps in understanding the etiology of type-2 diabetes. T2D is also a significant risk factor for coronary heart disease (CHD), but the biological pathways that explain the connection have remained somewhat murky. Now, in a large analysis of genetic data, publ ...

Related Articles