Cure for Type 1 diabetes imminent after Harvard stem-cell breakthrough
A cure for diabetes could be imminent after scientists discovered how to make huge quantities of insulin-producing cells, in a breakthrough hailed as significant as antibiotics.
Harvard University has, for the first time, managed to manufacture the millions of beta cells required for transplantation.
It could mean the end of daily insulin injections for the 400,000 people in Britain living with Type 1 diabetes.
And it marks the culmination of 23-years of research for Harvard professor Doug Melton who has been trying to find a cure for the disease since his son Sam was diagnosed with Type 1 diabetes as a baby.
“We are now just one pre-clinical step away from the finish line,” said Prof Melton.
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Asked about his children’s reaction he said: "I think like all kids, they always assumed that if I said I'd do this, I'd do it,
"It was gratifying to know that we can do something that we always thought was possible.”
The stem cell-derived beta cells are presently undergoing trials in animal models, including non-human primates, where they are still producing insulin after several months, Prof Melton said.
Type 1 diabetes is an autoimmune condition that causes the pancreas to stop producing Continue reading