Are Parkinson's Disease And Type 2 Diabetes Linked?

Are Parkinson's Disease and Type 2 Diabetes Linked?

Are Parkinson's Disease and Type 2 Diabetes Linked?

Two seemingly unrelated conditions may have more in common than researchers previously believed. A new study published in the August 2017 issue of The Lancet found that a common diabetes drug could affect the progression of Parkinson’s disease.
Parkinson’s disease, a neurodegenerative disorder that slowly limits a person's ability to control his or her movements, affects about 1 million people in the United States, according to the Parkinson’s Disease Foundation. The study authors of the Lancet article set out to find alternative treatments that could slow down disease advancement.
“All of the current treatments we have for Parkinson’s disease help manage the symptoms but don’t affect the progressive nature of the underlying disease,” explains one of the study's coauthors, Dilan Athauda, a bachelor of medicine and bachelor of surgery, a clinical researcher at the University College London, and a member of the Royal College of Physicians.
The research team set out to examine exenatide, an injection that treats type 2 diabetes by activating a gene that helps your body release insulin. It also slows down how fast your stomach empties after eating, which helps steady blood sugar. Animal studies suggest that this drug may also protect brain cells by activating these same receptors, boosting learning and memory, the researchers note.
The current study was a randomized, placebo-controlled trial, which has long been considered the gold standard in medical research. Half of human study subjects received placebo injections, while the other half got exenatide injections. Continue reading

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Preventing Diabetes Really Comes Down To A Few Simple Dietary Changes

Preventing Diabetes Really Comes Down To A Few Simple Dietary Changes

What are the steps to be taken to overcome diabetes? originally appeared on Quora: the place to gain and share knowledge, empowering people to learn from others and better understand the world.
Diabetes is a complex disease. There are many different types of diabetes including Type 1, Type 2, Pre-diabetes and gestational. The information here pertains to Type 2 diabetes and pre-diabetes. The most significant changes you can make are:
Avoid highly processed foods
People are consuming the greatest quantity of processed foods now more than any other time in history. However, most people don’t even know how dangerous they are. Recent studies show that processed foods are linked to many common diseases including diabetes, heart disease, certain cancers, and obesity. Can you believe so many diseases can come from the foods you eat? The processed foods I am talking about are anything made with white flour, artificial sweeteners, cakes, cookies, pastries, breakfast cereals, soft drinks, sugary “fruit” drinks, cheese food, frozen dinners, and processed meat products (sausage, bologna, bacon, packaged ham, etc.), canned food, and refined sugars (including high fructose corn syrup). Most processed foods are stripped of all nutrients and are high in sugar, fat, salt and calories.
Avoid red meat and most animal products
In addition to avoiding highly processed foods, eating fewer animal products will have a huge impact on your health. Eating fewer animal products is the key to preventing chronic diseases including obesity, heart disease and Type 2 diabetes because animal products Continue reading

FDA OKs Two Medicines for Cardiovascular Disease in Type 2 Diabetes

FDA OKs Two Medicines for Cardiovascular Disease in Type 2 Diabetes

People with diabetes have two to three times the increased risk for cardiovascular disease and death as those in the general population. Cardiovascular disease also accounts for two out of every three deaths in those with diabetes.
For people with Type 2 diabetes and pre-existing heart disease, the Food and Drug Administration (FDA) recently approved a change in the prescribing information for Jardiance (generic name empagliflozin) and Victoza (liraglutide), indicating they can be used to reduce the risk of cardiovascular disease in this group. Empagliflozin received an indication to only reduce cardiac death. Liraglutide received a broader indication, including reduction of heart attack, stroke, and death.
FDA Requires heart disease outcomes research
“Until 2008, the FDA approved diabetes medications based only their effects on blood sugar and evidence that they were reasonably safe,” said Steven Nissen, MD, chair of cardiovascular medicine at the Cleveland Clinic. “Since then, they have required the performance of additional trials focusing on cardiovascular disease outcomes.”
Most of the research on cardiovascular disease onoutcomes from Type 2 diabetes medications has shown limited or no benefits for the heart. So far, these are the only two exceptions, leading to the changes in prescribing information.
“The FDA staff and their committees thought that the evidence was sufficiently robust to warrant a label claim,” said Nissen. “From the point of view of the patients, this is a big deal because it means after decades of drug development, we have drugs for d Continue reading

A varied diet can prevent diabetes – but can you afford it?

A varied diet can prevent diabetes – but can you afford it?

In a study of over 25,000 adults with detailed information about their eating habits, people with a greater diversity of foods in their diet showed a 30% lower risk of developing type 2 diabetes over a ten-year period. Unfortunately, the diets with more variety were 18% more expensive than the less-varied ones.
A healthy diet is critical for preventing and managing type 2 diabetes. Type 2 diabetes affects around 415m adults globally; a figure that is expected to rise to 643m by 2040, mostly in low- and middle-income countries. So governments should support their citizen’s ability to eat well.
For several decades now, governments have recommended that people eat a varied diet. Global five-a-day campaigns stress the consumption of a variety of fruits and vegetables. The theory goes that consuming a variety of foods ensures that a person receives all the necessary vitamins, minerals and phytochemicals that are needed for the body to function and stay healthy. But, what do we really mean by a varied diet and what is its relationship with diabetes?
A varied diet is a healthier diet
Although dietary guidelines have for a long time recommended eating a variety of foods, scientists are not sure exactly what it is about eating a varied diet that might promote health. There has been research on how the variety of foods relate to the nutritional quality of a person’s diet, but little is known about whether the diversity of the diet is related to risk of chronic diseases such as type 2 diabetes.
For example, there are no studies on whether a diet containing foods from all five food Continue reading

Australian soft drinks linked to higher risk of diabetes, study shows

Australian soft drinks linked to higher risk of diabetes, study shows

Soft drinks sold in Australia have higher levels of glucose, which is linked to an increased chance of developing heart disease and type 2 diabetes, a study shows.
An international comparison, published in the Medical Journal of Australia, revealed several popular Australian soft drinks had glucose levels which were 22 per cent higher than those found in the United States.
Professor Bronwyn Kingwell, from the Baker Heart and Diabetes Institute, said the findings were particularly relevant for Australians who drank lots of soft drinks.
"Given that glucose, but not fructose, rapidly elevates plasma glucose and insulin, regular consumption of Australian soft drinks has potential health implications regarding type 2 diabetes and its complications," she said.
Many leading health organisations — including the Australian Medical Association, the Royal Australian College of General Practitioners and the Consumers Health Forum — have called on the Federal Government to consider introducing a tax on sugar-sweetened beverages, such as soft drinks, to combat rising rates of obesity.
"Given the high rate of consumption of sugar-sweetened beverages and type 2 diabetes and heart disease, these new findings are of significant concern," Professor Kingwell said.
In Australia, soft drinks are usually sweetened with sucrose, while in the US, high-fructose corn syrup is the main sweetener.
Professor Kingwell said the health effects of having too much high-fructose syrup were well known, including a build-up of fat in the liver.
But she said not as much was known about the health risks of co Continue reading

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