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Apple Is 'Secretly Working' On Diabetes Treatment

Apple Is 'Secretly Working' on Diabetes Treatment

Apple Is 'Secretly Working' on Diabetes Treatment

Apple has hired a team of biomedical engineers as part of a secret initiative, initially envisioned by late Apple co-founder Steve Jobs, to develop sensors to treat diabetes, CNBC reported, citing three people familiar with the matter.
An Apple spokeswoman declined to comment.
The engineers are expected to work at a nondescript office in Palo Alto, California, close to the corporate headquarters, CNBC said.
The news comes at a time when the line between pharmaceuticals and technology is blurring as companies are joining forces to tackle chronic diseases using high-tech devices that combine biology, software and hardware, thereby jump-starting a novel field of medicine called bioelectronics.
Last year, GlaxoSmithKline and Google parent Alphabet unveiled a joint company aimed at marketing bioelectronic devices to fight illness by attaching to individual nerves.
U.S. biotech firms Setpoint Medical and EnteroMedics have already shown early benefits of bioelectronics in treating rheumatoid arthritis and suppressing appetite in the obese.
Other companies playing around the idea of bioelectronics include Medtronic, Proteus Digital Technology, Sanofi SA and Biogen.
The company's shares were marginally up after the bell on Wednesday. Continue reading

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Cities Are the Front Line in the Global Diabetes Epidemic

Cities Are the Front Line in the Global Diabetes Epidemic

Today, 437 million people worldwide have type 1 or type 2 diabetes. New estimates published this month show that three-quarters of a billion people could have the disease by 2045 — and cities are the front line of this challenge. As the growth fast becomes unmanageable for health systems, shortening the lives of millions of urban citizens and constraining economic growth, Novo Nordisk is working with a coalition of major cities to bend the curve on type 2 diabetes. We’re calling for local political and health leaders of all cities to ask what it will take to change the trajectory of the disease in their area and to put into practice the new models that we are forging.
A rapidly urbanizing world is changing not just where we live but also how we live. As my predecessor at Novo Nordisk wrote, the way cities are designed, built, and run creates health benefits for citizens — but critically it also creates risks. Towns and cities, where half of the world’s population now lives, are home to two-thirds of people with diabetes. That’s why when we initiated the Cities Changing Diabetes program in 2014, we set out to put a spotlight on urban diabetes. This effort has grown into a global partnership of nine major cities, home to over 75 million people, and over 100 expert partners united in the fight against urban diabetes.
Without concerted action, health systems around the world will reach a point in coming decades when they won’t be able to effectively treat patients sustainably. We conservatively estimate that the related costs of diabetes — including medication, su Continue reading

Exercise and Glucose Metabolism in Persons with Diabetes Mellitus: Perspectives on the Role for Continuous Glucose Monitoring

Exercise and Glucose Metabolism in Persons with Diabetes Mellitus: Perspectives on the Role for Continuous Glucose Monitoring

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Continuous Glucose Monitoring Technology
Given the problems of exercise-associated disturbances in glycemia described earlier and the risk for hypoglycemia unawareness, frequent monitoring of glucose is essential for active individuals with type 1 diabetes. Most exercise-related guidelines recommend self-monitoring of blood glucose (SMBG) with capillary blood at least twice before exercise and every 30 min during the exercise as well as hours into recovery.2 This recommendation for frequent SMBG is difficult to adhere to for some, because it requires a pause in activity, a limitation that would be ameliorated with CGM. Moreover, a fear of exercise associated hypoglycemia is a major barrier to exercise participation in adults5 and in youth,6 and CGM might help increase self-efficacy during sport. Finally, CGM has the potential to assist active persons with diabetes by recording exercise-associated changes in blood glucose levels, and this information may be useful in developing appropriate insulin and carbohydrate modifications during times of increased activity. A brief overview of CGM technology is provided in the next section.
Continuous glucose monitoring devices have been available since the late 1990s and were developed for the measurement of interstitial glucose levels in subcutaneous tissue as a reflection of circulating glucose concentrations. The main components of CGM include a transcutaneous sensor inserted into the abdomen or arm, a transmitter, and a receiver that is typically worn on a belt or carried in a pocket. With this technology, the implanted sen Continue reading

3 Lessons Running 5Ks Has Taught Me About Living With Diabetes

3 Lessons Running 5Ks Has Taught Me About Living With Diabetes

In 2013, three years after I was diagnosed with type 2 diabetes, I was awarded a Fulbright grant that allowed me to live in the United Arab Emirates for that academic year. In addition to teaching and conducting research, my goal was to explore the country and break from my comfort zone.
By the time I signed up for the Dubai Women’s Run, I had already completed a variety of firsts. I rode a camel for the first time, drank camel’s milk, sandboarded in the desert, and visited the top of the world’s tallest skyscraper, the Burj Khalifa. I thought that a 5K race would fit well on this list.
When I finished my first 5K, I immediately developed a love for running. But surprisingly, this new interest wasn’t the result of a natural talent for racing. In fact, the only positive result from my first 5K was that I completed it within my goal time of 45 minutes. Aside from that, it was a classic example of what not to do in a 5K race: I hadn’t trained properly, I got caught up in the crowd’s excitement and lost my pace, I paid more attention to other runners than to myself, I exerted all my energy by the second kilometer, and, when I crossed the finish line, I fell to the ground in agony. I felt whipped, and every muscle in my body wept in unison with me.
Even as I lay in the grass in anguish, I knew that I had to do it again. I perceived the race as a living metaphor because I saw so many life lessons in that first race, especially as a person living with type 2 diabetes. I promised myself that I would train better, have the perfect music playlist, remember my earphones, p Continue reading

Canada Still Has A Chance To Reverse Its Diabetes Epidemic

Canada Still Has A Chance To Reverse Its Diabetes Epidemic

Earlier this year I retired after a dozen years as president of Innovative Medicines Canada. Shortly after I took an assignment with the Canadian Diabetes Association and the opportunity to work on what is one of Canada's largest and most perplexing challenges: our diabetes epidemic.
For years public health authorities have been sounding the alarm. But the tone has become more urgent in recent years -- with terms like "burning platform" and "crisis" increasingly used.
Since 2000, the prevalence of diabetes has more than doubled. In the next 10 years, both prevalence and direct health-care costs for diabetes are projected to grow by more than 40 per cent.
In 2016, an estimated 29 per cent of Canada's population have either diabetes or prediabetes. The prevalence of diabetes in Canada is now slightly higher than in the United States. In fact, Canada has the second highest prevalence rates in recent study of 34 Organization for Economic Cooperation and Development (OECD) countries.
This is having a profound impact on the health of millions of Canadians, and costs our health-care system billions of dollars per year. In medical and human terms, the numbers are staggering:
Diabetes reduces the average lifespan by five to 15 years. It is estimated that one of 10 deaths in Canadian adults was attributable to diabetes in 2008-2009.
People with diabetes are over three times more likely to be hospitalized with cardiovascular disease, 12 times more likely to be hospitalized with end-stage renal disease and over 20 times more likely to be hospitalized for a non-traumatic lower limb ampu Continue reading

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