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Why Does Potassium Increase In Metabolic Acidosis?

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Effect Of Metabolic Acidosis On Renal Tubular Sodium Handling In Rats As Determined By Lithium Clearance

PrintversionISSN 0100-879XOn-lineversionISSN 1414-431X Braz J Med Biol Resvol. 31n. 10Ribeiro PretoOct.1998 Braz J Med Biol Res, October 1998, Volume 31(10) 1269-1273 (Short Communication) Effect of metabolic acidosis on renal tubular sodium handling in rats as determined by lithium clearance L.F. Menegon1, J.F. Figueiredo2 and J.A.R. Gontijo1 1Disciplina de Medicina Interna, Laboratrio de Balano Hidro-Salino, and 2Disciplina de Nefrologia, Laboratrio de Conservao de rgos, Ncleo de Medicina e Cirurgia Experimental, Departamento de Clinica Mdica, Faculdade de Cincias Mdicas, Universidade Estadual de Campinas, Campinas, SP, Brasil Systemic metabolic acidosis is known to cause a decrease in salt and water reabsorption by the kidney. We have used renal lithium clearance to investigate the effect of chronic, NH4Cl-induced metabolic acidosis on the renal handling of Na+ in male Wistar-Hannover rats (200-250 g). Chronic acidosis (pH 7.16 0.13) caused a sustained increase in renal fractional Na+ excretion (267.9 36.4%), accompanied by an increase in fractional proximal (113.3 3.6%) and post-proximal (179.7 20.2%) Na+ and urinary K+ (163.4 5.6%) excretion when compared to control and pair- Continue reading >>

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  1. AnnieC

    Keto insomnia?

    I've been doing this for 5 days now and I had a lot of trouble sleeping unlike before where I had no trouble falling asleep. Have any of you experienced this?

  2. maresf16

    Yea when I was "adjusting" I kept getting massive headaches and feverish. I woke up every two hours if I was sleeping reasonably well, and sometimes I just drifted in and out of consciousness by the minutes. It's passed now, but I don't remember it taking 5 days.

  3. AnnieC

    Originally Posted by maresf16
    Yea when I was "adjusting" I kept getting massive headaches and feverish. I woke up every two hours if I was sleeping reasonably well, and sometimes I just drifted in and out of consciousness by the minutes. It's passed now, but I don't remember it taking 5 days.

    How long have you been doing it?
    Maybe it takes longer for me because my metabolism is more screwed up eheh. I've been a mega-sugar addict all my life. This is a HUGE change for me. At least, I don't feel as sluggish now as I did on day 3 so that's pretty good!

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Potassium Jeremy E. Kaslow, M.d.

Potassium is an extremely valuable electrolyte essential to heart and kidney function as well as to the maintenance of blood and urine pH. It is the chief electrolyte in the fluid of cells. In fact, only a small part of the total body potassium is contained in the serum. Serum potassium values range from 3.5 to 5.0 mmol/L while the concentration inside the red blood cell is at least l5 to 20 times this amount. While only a part of the total body potassium is found in the serum, proper serum values are critical to normal physiology, especially adrenal, heart and renal functions. Potassium should always be viewed in relation to the other electrolytes. Adrenal Cortex under function. With hypoadrenia, you may get dizzy when you sit or stand quickly, fatigue (especially feeling tired in the morning), crave salt or salty foods, have a low systolic blood pressure, experience food and/or environmental sensitivities, feel weak or tired after colds, stress or exercise, sweat easily with exertion, get shortness of breath after very minimal exertion even though you are in shape, get colds and upper respiratory tract infections easily, etc. Aldosterone is produced by the adrenal cortex, with i Continue reading >>

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  1. KetogenicJoseph

    Hey y'all!

    I am trying to find out which tester thingy thing I should get ( i know very scientific term). One of my friends who is diabetic said that they don't make such a thing but I see people on here who have those devices. Can anyone recommend a good solid one I should pick up?

  2. entirelyem

    Precision Xtra meter measures blood glucose and blood ketones. Just buy the appropriate strips and test.

  3. KetogenicJoseph

    Right on! Thank you mucho! I'll pick one of these up my next pay day!

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A Mitochondrial Etiology of Metabolic and Degenerative Diseases, Cancer and Aging Air date: Wednesday, April 02, 2014, 3:00:00 PM Category: Wednesday Afternoon Lectures Runtime: 01:10:05 Description: Wednesday Afternoon Lecture Series For half a millennium Western medicine has focused on anatomy and for the past century on nuclear DNA (nDNA), Mendelian, genetics. While these concepts have permitted many biomedical advances, they have proven insufficient for understanding the common "complex" diseases. Life requires energy, 90 percent of which comes from the mitochondrion. The mitochondrial genome consists of thousands of copies of the maternally inherited mitochondrial DNA (mtDNA) plus 1,000--2,000 nDNA genes. The mtDNA has a very high mutation rate, but the most deleterious mutations are removed by an ovarian prefertilization selection system. Hence, functional mtDNA variants are constantly being introduced into the human population, the more deleterious resulting in recent maternally inherited diseases. The milder mtDNA variants have accumulated sequentially as women spread throughout Africa and migrated out to colonize Eurasia and the Americas. Some ancient mtDNA variants alter

Metabolic Acidosis: Practice Essentials, Background, Etiology

Metabolic acidosis is a clinical disturbance characterized by an increase in plasma acidity. Metabolic acidosis should be considered a sign of an underlying disease process. Identification of this underlying condition is essential to initiate appropriate therapy. (See Etiology, DDx, Workup, and Treatment.) Understanding the regulation of acid-base balance requires appreciation of the fundamental definitions and principles underlying this complex physiologic process. Go to Pediatric Metabolic Acidosis and Emergent Management of Metabolic Acidosis for complete information on those topics. An acid is a substance that can donate hydrogen ions (H+). A base is a substance that can accept H+ ions. The ion exchange occurs regardless of the substance's charge. Strong acids are those that are completely ionized in body fluids, and weak acids are those that are incompletely ionized in body fluids. Hydrochloric acid (HCl) is considered a strong acid because it is present only in a completely ionized form in the body, whereas carbonic acid (H2 CO3) is a weak acid because it is ionized incompletely, and, at equilibrium, all three reactants are present in body fluids. See the reactions below. Th Continue reading >>

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  1. HighCaliber

    Hello Community,
    I have something weird going on here and I can't put my finger on it.
    I am getting a lower left & right back pain and can't explain it. It is a dull pain and would register at about a 1 out of 10 on a pain scale. As my signature states below, pain calls attention to something that is unhealthy.
    I have been rather active lately and have been on Animal-Pak vitamins. However, I also have been drinking a LOT of water for the past two weeks, about 1.5 to 2 gallons a day. (I weigh 311Lbs.) I guzzle H2O at the gym.
    Aah, I don't want to even think this is a kidney related issue from being low carb for only 12 days now. Don't beat me up for even mentioning that its relation to my SKD. I have been eating STRICTLY and maintaining a sub-20 carb intake per day. I feel amazing and have lost about 11 pounds so far.
    Sorry for the rant, just needed to vent some steam about this nagging issue.
    I just downed 32oz of H20 while writing this post and I'm hoping for the best.
    Thank you all,
    -HighCaliber
    Note: I have not carbed up yet, I originally started the BFFM style of carb ups for training and every third day nevertheless I was gaining/maintaining too much fat so I discontinued that regimen in September of 2007.

  2. PyroBurns

    I get this too sometimes, and I think it might be because of.... uh... issues going number two for me (sorry for the TMI). I imagine my intestines being too full and pushing on my kidneys. Maybe that could be it?

  3. PSMF

    IMO don't drink more then 1 gallon of water, start taking lots of electrolytes in your drinking water and then report back.
    See Morton salt substitute and Morton light salt for cheep source of potassium chloride and sodium chloride and iodine. Start eating red meat for zinc.

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