Why Does Acute Kidney Injury Cause Metabolic Acidosis?

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

Ethylene Glycol Toxicity A Rare Cause Of High Anion Gap Metabolic Acidosis In Australia

ETHYLENE GLYCOL TOXICITY A RARE CAUSE OF HIGH ANION GAP METABOLIC ACIDOSIS IN AUSTRALIA ETHYLENE GLYCOL TOXICITY A RARE CAUSE OF HIGH ANION GAP METABOLIC ACIDOSIS IN AUSTRALIA GJ WILSON1,2, J ROWLAND1, MR DOWLING1, L FRANCIS3, GT JOHN1,2,AL KARK1,2 1Department of Renal Medicine, Royal Brisbane and Womens Hospital, Herston, Queensland;2School of Clinical Medicine, University of Queensland, Herston, Queensland;3Department of Pathology, Royal Brisbane and Womens Hospital, Herston, Queensland Background: Ethylene glycol toxicity is a well-known cause of acute kidney injury (AKI) and high anion gap metabolic acidosis. However, it is a rare presentation in Australia with only 22 cases reported in 2014. The diagnosis of ethylene glycol toxicity is challenging in the absence of a history of ingestion and can be misdiagnosed as lactic acidosis which, due to structural similarities with glycolate, causes falsely elevated lactate levels on some instruments. Case Report: A 36 year-old female presented to the emergency department with an altered level of consciousness and tachypnoea requiring urgent intubation. She was anuric and had an AKI (creatinine 182 umol/L). An iSTAT venous blood gas de Continue reading >>

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  1. SecureHandle

    I've skimmed the internet with nothing to show for it. Can anyone explain the difference? Is there any?

  2. [deleted]

    Keto is a descriptive term for any general low-carb, high-fat diet that should induce nutritional ketosis.
    Atkins is a detailed, specifically regimented weight-loss program that restricts many specific foods throughout its various stages and also restricts overall carbohydrate intake. It often induces nutritional ketosis and could be considered a ketogenic diet.

  3. bidnow

    Keto is the Induction phase of Atkins. Dr. Atkins told his patients that they didn't need to count maros (except carbs) at first for the same reason you see here with overweight people saying that they can't or won't count macros.

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Acute kidney injury (also called acute renal failure) nursing NCLEX review lecture on the nursing management, stages, pathophysiology, and causes (prerenal, intrarenal, postrenal). What is Acute Kidney Injury? It is the SUDDEN decrease in renal function that leads to the build up of waste in the blood, fluid overload, and electrolyte imbalances. What are the causes of Acute Kidney Injury? There are three causes, which are based on location. The first is known as prerenal injury and this is an issue with the perfusion to the kidneys that leads to decreased renal function. A second cause is known as intrarenal injury, and this is due to damage to the nephrons of the kidney. Lastly, postrenal injury is due to a blockage located in the urinary tract after the kidney that can extend to the urethra. This is causing the back flow of urine, which increases the pressure and waste in the kidneys. Stages of Acute Kidney Injury: There are four stage of acute kidney injury, which include initiation, oliguric, diuresis, and recovery stage. The initiation stage starts when a cause creates an injury to the kidney and then signs and symptoms start to appear. This leads to the oliguric stages. The p

Acute Kidney Injury - Wikipedia

Pathologic kidney specimen showing marked pallor of the cortex, contrasting to the darker areas of surviving medullary tissue. The patient died with acute kidney injury. Acute kidney injury (AKI), previously called acute renal failure (ARF), [1] [2] is an abrupt loss of kidney function that develops within 7 days. [3] Its causes are numerous. Generally it occurs because of damage to the kidney tissue caused by decreased kidney blood flow (kidney ischemia ) from any cause (e.g., low blood pressure ), exposure to substances harmful to the kidney , an inflammatory process in the kidney, or an obstruction of the urinary tract that impedes the flow of urine. AKI is diagnosed on the basis of characteristic laboratory findings, such as elevated blood urea nitrogen and creatinine , or inability of the kidneys to produce sufficient amounts of urine . AKI may lead to a number of complications, including metabolic acidosis , high potassium levels , uremia , changes in body fluid balance , and effects on other organ systems , including death. People who have experienced AKI may have an increased risk of chronic kidney disease in the future. Management includes treatment of the underlying caus Continue reading >>

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  1. cccp

    I know this question has been asked a million times before, but my search for "carb up day diet" returns a 404 error.
    I'm on the third week of Keto right now, and just wanted to know if I should carb up sometime soon. I heard good and bad things about it. Some people say you will be thrown out of ketosis for a couple of days because your liver will be glucosed up, and other people say that you need it for muscle fullness or something?? Help me on this please.

  2. ~SC~ Guest

    u will be out of ketosis, but that's not a problem as u can quickly return within a day or so with ancillaries like ala, vanadyl sulfate, and exercise.
    Carb ups, in my opinion, are needed to keep muscle and muscle size. As well, your metabolism will slow (BMR) in the absence of carbs for long periods of time. U need to avoid this by carbing up at least one full day out of the week on a full ketogenic diet.
    Interestingly, if u are a bodybuilder or looking to gain some shape, a CKD may not be what you wish to do. U may want to look into a TKD, or something similar.

  3. cccp

    So it is needed pretty much just to boost your metabolism when it slows down too much, huh? that makes sense. Isn't once a week kind of often, though? Does your metabolism slows down that much in one week? Especially if I'm taking xenadrine on keto?

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Understand acute kidney injury (formerly called acute renal failure) with this clear explanation from Dr. Seheult of http://www.medcram.com. This series covers causes, symptoms, diagnosis and treatment of acute renal failure. The difference between pre-renal and post-renal failure, and the BUN Creatinine ratio are also illustrated. This video 1 of 3 on acute kidney injury. Speaker: Roger Seheult, MD Clinical and Exam Preparation Instructor Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine. Co-founder of http://www.medcram.com MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded. Subscribe: https://www.youtube.com/subscription_... Recommended Audience: Health care professionals and medical students including physicians

Metabolic Acidosis Aggravates Experimental Acute Kidney Injury

Volume 146 , 1 February 2016, Pages 58-65 Metabolic acidosis aggravates experimental acute kidney injury Ischemia/reperfusion (I/R) injury and metabolic acidosis (MA) are two critical conditions that may simultaneously occur in clinical practice. The result of this combination can be harmful to the kidneys, but this issue has not been thoroughly investigated. The present study evaluated the influence of low systemic pH on various parameters of kidney function in rats that were subjected to an experimental model of renal I/R injury. Metabolic acidosis was induced in male Wistar rats by ingesting ammonium chloride (NH4Cl) in tap water, beginning 2days before ischemic insult and maintained during the entire study. Ischemia/reperfusion was induced by clamping both renal arteries for 45min, followed by 48h of reperfusion. Four groups were studied: control (subjected to sham surgery, n=8), I/R (n=8), metabolic acidosis (MA; 0.28M NH4Cl solution and sham surgery, n=6), and MA+I/R (0.28M NH4Cl solution plus I/R, n=9). Compared with I/R rats, MA+I/R rats exhibited higher mortality (50 vs. 11%, p=0.03), significant reductions of blood pH, plasma bicarbonate (pBic), and standard base excess Continue reading >>

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  1. twosix

    Where can I buy ketostix? Been to many pharmacies like Guardian and NTUC around city area and all of them do not carry it.

  2. Gustoftw

    I bought mine from NTUC unity bukit timah plaza

  3. twosix

    Gustoftw wrote:
    I bought mine from NTUC unity bukit timah plaza Thanks, but the location is far from my place.

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