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Why Does Acidosis Cause Vomiting?

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high blood sugar, low blood pH, and ketoacids in either the blood or urine. The primary treatment of DKA is with intravenous fluids and insulin. Depending on the severity, insulin may be given intravenously or by injection under the skin. Usually potassium is also needed to prevent the development of low blood potassium. Throughout treatment blood sugar and potassium levels should be regularly checked. Antibiotics may be required in those with an underlying infection. In those with severely low blood pH, sodium bicarbonate may be given; however, its use is of unclear benefit and typically not recommended. Rates of DKA vary around the world. About 4% of people with type 1 diabetes in United Kingdom develop DKA a year, while in Malaysia the condition affects about 25% a year. DKA was first described in 1886 and, until the introduction of insulin therapy in the 1920s, it was almost universally fatal. The risk of death with adequate and timely treatment is currently around 1–4%. Up to 1% of children with DKA develop a complication known as cerebral edema. The symptoms of an episode of diabetic ketoacidosis usually evolve over a period of about 24 hours. Predominant symptoms are nausea and vomiting, pronounced thirst, excessive urine production and abdominal pain that may be severe. Those who measure their glucose levels themselves may notice hyperglycemia (high blood sugar levels). In severe DKA, breathing becomes labored and of a deep, gasping character (a state referred to as "Kussmaul respiration"). The abdomen may be tender to the point that an acute abdomen may be suspected, such as acute pancreatitis, appendicitis or gastrointestinal perforation. Coffee ground vomiting (vomiting of altered blood) occurs in a minority of people; this tends to originate from erosion of the esophagus. In severe DKA, there may be confusion, lethargy, stupor or even coma (a marked decrease in the level of consciousness). On physical examination there is usually clinical evidence of dehydration, such as a dry mouth and decreased skin turgor. If the dehydration is profound enough to cause a decrease in the circulating blood volume, tachycardia (a fast heart rate) and low blood pressure may be observed. Often, a "ketotic" odor is present, which is often described as "fruity", often compared to the smell of pear drops whose scent is a ketone. If Kussmaul respiration is present, this is reflected in an increased respiratory rate.....

Pediatric Diabetic Ketoacidosis

Practice Essentials Diabetic ketoacidosis, in pediatric and adult cases, is a metabolic derangement caused by the absolute or relative deficiency of the anabolic hormone insulin. Together with the major complication of cerebral edema, it is the most important cause of mortality and severe morbidity in children with diabetes. Signs and symptoms Symptoms of acidosis and dehydration include the following: Symptoms of hyperglycemia, a consequence of insulin deficiency, include the following: Patients with diabetic ketoacidosis may also have the following signs and symptoms: Cerebral edema Most cases of cerebral edema occur 4-12 hours after initiation of treatment. Diagnostic criteria of cerebral edema include the following: Major criteria include the following: Minor criteria include the following: See Clinical Presentation for more detail. Laboratory studies The following lab studies are indicated in patients with diabetic ketoacidosis: Imaging studies Head computed tomography (CT) scanning - If coma is present or develops Chest radiography - If clinically indicated Electrocardiography Electrocardiography (ECG) is a useful adjunct to monitor potassium status. Characteristic changes ap Continue reading >>

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  1. Jennifer72

    Body Temperature, Glucose & Ketones

    When my blood sugar used to be over 250 to 350 mg/dL all the time (24/7), I remember how hot I got. My body temperature increased and I had to bump the AC down to 69F in the house and turn up the ceiling fans.
    Since dietary change, I've dropped all my insulin and oral meds, (in the past 3 months), and I've maintained 109 to 135 mg/dL all day without effort (LCHF ketogenic intermitent fasting diet).
    I normally feel pretty cool when I get down to 110 mg/dL and have the house temp at 73F.
    Feeling a bit warm today but blood sugar was only 133 mg/dL.
    Here's my question, can higher blood ketone levels (BHB), cause an increase in metabolism as well, generating more body heat? My ketones are up, sugar not that high. Does my body want to increase it's metabolism since my insulin levels are now relatively low and so many fatty acids are escaping from the fat cells?
    I've been urinating a lot and lost 15 pounds in the past 8 days.. mostly water, since I returned to my ketogenic intermittent fasting diet (9 days ago). I pee as much as I did when I was peeing out uncontrolled diabetes sugars above 250-350 mg/dL all day. But this time it's due to the fatty acids & ketones? I don't mind the weight loss at all btw.. got 200 more pounds to lose.

  2. furball64801

    I have been in ketosis and never experienced being hot. Not sure what is causing it for sure.

  3. Jennifer72

    Originally Posted by furball64801
    I have been in ketosis and never experienced being hot. Not sure what is causing it for sure. Do you always pee a lot on ketosis? Or only when getting keto adapted? I'm relatively new to all this and perhaps not yet fully keto adapted? but my bhb was 1.8 mmol/L the ohter night. Urine ketones are usually around 4.

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Anion gap usmle - anion gap metabolic acidosis normal anion gap metabolic acidosis

Metabolic Acidosis: Causes, Symptoms, And Treatment

The Terrible Effects of Acid Acid corrosion is a well-known fact. Acid rain can peel the paint off of a car. Acidifying ocean water bleaches and destroys coral reefs. Acid can burn a giant hole through metal. It can also burn holes, called cavities, into your teeth. I think I've made my point. Acid, regardless of where it's at, is going to hurt. And when your body is full of acid, then it's going to destroy your fragile, soft, internal organs even more quickly than it can destroy your bony teeth and chunks of thick metal. What Is Metabolic Acidosis? The condition that fills your body with proportionately too much acid is known as metabolic acidosis. Metabolic acidosis refers to a physiological state characterized by an increase in the amount of acid produced or ingested by the body, the decreased renal excretion of acid, or bicarbonate loss from the body. Metabolism is a word that refers to a set of biochemical processes within your body that produce energy and sustain life. If these processes go haywire, due to disease, then they can cause an excess production of hydrogen (H+) ions. These ions are acidic, and therefore the level of acidity in your body increases, leading to acidem Continue reading >>

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  1. Andrew_Schaefer

    For as long as I can remember, I’ve had chronic canker sores in my mouth on my inner cheeks / tongue. I almost always had one, but more often than not I would have 3+ in my mouth. They would keep me from talking, eating, and from pretty much enjoying any part of life. It’s hard for me to articulate how debilitating and frustrating it has actually been to have this problem for almost 30 years.
    For decades, doctors have told me that there is no cure for canker sores. I’ve been prescribed numerous pastes / balms that will numb the pain for a short period of time, but nothing that actually fixes the problem. And everyone I know has a home remedy that “works every time,” but actually works “never.” But I’ve been eating this way for about a month now and, after the first three days or so, I haven’t had a single sore. I honestly can’t remember the last time (if ever) that I’ve gone this long without having one.
    It’s truly unbelievable. I can talk and eat without pain. Hell, I can sit motionless without pain. It feels like a huge weight has been lifted off my back. Hard to imagine that I could have been feeling this way all the time.
    I’m not sure what I mean to get out of this post. But, I guess if anyone in the forum has a chronic condition like mine and is on the fence about trying this WOE, there is little to lose by giving it a shot and a whole lot to gain. As the saying goes, the best time to have started eating this way was 25 years ago. The second best time is today.

    Oh, and thank you everyone! I never would have started without the people in this community! It is not an exaggeration to say that I owe you all my life!

  2. EZB

    Before you were keto, did you eat a lot of acidic fruits?

  3. Andrew_Schaefer

    No, not really. I get that question a lot actually, but the mouth pain pretty much precluded anything too acidic.

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What is KETOACIDOSIS? What does KETOACIDOSIS mean? KETOACIDOSIS meaning - KETOACIDOSIS definition - KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids. The two common ketones produced in humans are acetoacetic acid and ß-hydroxybutyrate. Ketoacidosis is a pathological metabolic state marked by extreme and uncontrolled ketosis. In ketoacidosis, the body fails to adequately regulate ketone production causing such a severe accumulation of keto acids that the pH of the blood is substantially decreased. In extreme cases ketoacidosis can be fatal. Ketoacidosis is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Prolonged alcoholism may lead to alcoholic ketoacidosis. Ketoacidosis can be smelled on a person's breath. This is due to acetone, a direct by-product of the spontaneous decomposition of acetoacetic acid. It is often described as smelling like fruit or nail polish remover. Ketosis may also smell, but the odor is usually more subtle due to lower concentrations of acetone. Treatment consists most simply of correcting blood sugar and insulin levels, which will halt ketone production. If the severity of the case warrants more aggressive measures, intravenous sodium bicarbonate infusion can be given to raise blood pH back to an acceptable range. However, serious caution must be exercised with IV sodium bicarbonate to avoid the risk of equally life-threatening hypernatremia. Three common causes of ketoacidosis are alcohol, starvation, and diabetes, resulting in alcoholic ketoacidosis, starvation ketoacidosis, and diabetic ketoacidosis respectively. In diabetic ketoacidosis, a high concentration of ketone bodies is usually accompanied by insulin deficiency, hyperglycemia, and dehydration. Particularly in type 1 diabetics the lack of insulin in the bloodstream prevents glucose absorption, thereby inhibiting the production of oxaloacetate (a crucial molecule for processing Acetyl-CoA, the product of beta-oxidation of fatty acids, in the Krebs cycle) through reduced levels of pyruvate (a byproduct of glycolysis), and can cause unchecked ketone body production (through fatty acid metabolism) potentially leading to dangerous glucose and ketone levels in the blood. Hyperglycemia results in glucose overloading the kidneys and spilling into the urine (transport maximum for glucose is exceeded). Dehydration results following the osmotic movement of water into urine (Osmotic diuresis), exacerbating the acidosis. In alcoholic ketoacidosis, alcohol causes dehydration and blocks the first step of gluconeogenesis by depleting oxaloacetate. The body is unable to synthesize enough glucose to meet its needs, thus creating an energy crisis resulting in fatty acid metabolism, and ketone body formation.

Diabetic Ketoacidosis

The Facts Diabetic ketoacidosis (DKA) is a condition that may occur in people who have diabetes, most often in those who have type 1 (insulin-dependent) diabetes. It involves the buildup of toxic substances called ketones that make the blood too acidic. High ketone levels can be readily managed, but if they aren't detected and treated in time, a person can eventually slip into a fatal coma. DKA can occur in people who are newly diagnosed with type 1 diabetes and have had ketones building up in their blood prior to the start of treatment. It can also occur in people already diagnosed with type 1 diabetes that have missed an insulin dose, have an infection, or have suffered a traumatic event or injury. Although much less common, DKA can occasionally occur in people with type 2 diabetes under extreme physiologic stress. Causes With type 1 diabetes, the pancreas is unable to make the hormone insulin, which the body's cells need in order to take in glucose from the blood. In the case of type 2 diabetes, the pancreas is unable to make sufficient amounts of insulin in order to take in glucose from the blood. Glucose, a simple sugar we get from the foods we eat, is necessary for making the Continue reading >>

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  1. Kodah007

    I'm new here and may be too late for this discussion. Our 8 year old husky was in diabetic ketoacidosis 4 days ago. 3 nights on fluid at vet, started insulin, steroids and pain meds. She cannot walk on her own, like her hind legs are totally numb. She's also been going potty on herself at vet. I'm really worried she won't get better and I don't have the time to be carrying her around and/or cleaning up messes. How long can I expect this yo last? Do all dogs recover?

  2. k9diabetes

    Hi,
    I decided to copy your question to a thread of your own... so sorry such a scary experience brings you here.
    If she can get past the ketoacidosis, whatever leg problems and incontinence coming from neuropathy should gradually diminish with better blood sugar.
    Most dogs I've seen have fully recovered from neuropathy. Sometimes a dog has other spinal issues also involved and in those cases the problems associated with neuropathy go away so things get better.
    So, yes, chances are very good she can get back to normal. Beaming her Get Well wishes.... hang in there.
    Natalie

  3. Rubytuesday

    Hi there,
    If the sole cause of weakness in the backend is diabetic neuropathy, and it could well be, they can recover and go on to be healthy diabetics. Surviving diabetic ketoacidosis can take quite a toll on them and I would not judge her condition now as long as she isn't suffering. weakness isn't a lot of fun for either of you but they can get back to normal.
    I will attach some info about a key role a specific form of B-12 (methylcobalimin) plays in recovery.
    Many dogs here have struggled with hind end weakness. Has the B-12 helped in these cases? I don't know, but it hasn't hurt.
    The single most important thing you can do now is to find the best dose to manage her diabetes. This can be a trying process. To tell the truth this was the best place I found for getting the best information about how to go about that. My dog wasn't an easy diabetic and frankly my vets didn't know what to do to make our situation better. Folks here helped us tremendously. The collective knowledge and creativity was a godsend.
    I found that I couldn't rely on just the guidance from my vet and some stories I have heard have been downright scary. The best advice I can give is read a lot from the home page and threads, ask a bunch of questions and if at all possible give home testing a try. Doing your own home testing not only saves you money and keeps your dog safe, but it will help you progess through the regulation process a bit quicker.
    I will go grab the home page link for you and the b-12 info. Just don't want to lose this post. The ipad sometimes doesn't like me switching around.
    Tara
    ____________

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