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Why Doctors Are Not Recommending Metformin

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Safe Prescribing Of Metformin In Diabetes

Metformin is the first-line pharmacological therapy for type 2 diabetes. It is the only glucose-lowering oral drug that has been shown to reduce mortality in patients with diabetes. The most common adverse effect is gastrointestinal upset. Starting at a low dose and increasing it slowly reduces this risk. Taking metformin with food also helps. Numerous contraindications to the use of metformin are listed in the product information, including reduced renal function. Strict adherence to these recommendations may deny a valuable drug to many patients. Introduction Metformin lowers both fasting and postprandial blood glucose. It reduces hepatic glucose output 1 and increases peripheral glucose uptake, and may delay intestinal glucose absorption. Its use is not associated with weight gain and hypoglycaemia is extremely rare when metformin is used on its own. It lowers triglyceride concentrations and has small but beneficial effects on total and high-density lipoprotein cholesterol. In the UK Prospective Diabetes Study metformin reduced diabetes-related and all-cause mortality, and reduced the risk of myocardial infarction in obese patients with type 2 diabetes when used as first-line th Continue reading >>

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Popular Questions

  1. fenlady

    Help - I am really struggling to control my Type 2 with diet alone, and am in a wheelchair so can't exercise much. My last Hba1c was 36 (5.4). I know this is a good reading, but my weight keeps going up even so. And I'm only eating 1350 calories a day. I really think metformin would help me to control my weight as well as my blood sugars, but the doctor won't prescribe it and won't say why! Can anyone explain this - what does my Hba1c have to be before I can be offered metformin? Thanks.

  2. ally1

    I do think it depends on your blood test results

  3. Brunneria

    My surgery has to follow the rules set them by the local NHS governing body (are they still called primary care trusts, or have they changed name yet again?) - and their rule is that metformin is only prescribed to diagnosed diabetics with an hba1c above 48
    Some people have posted that their surgeries refuse to prescribe met until the hba1c hits 53

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