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What Is The Opposite Of Acidosis?

Acidosis | Define Acidosis At Dictionary.com

Acidosis | Define Acidosis At Dictionary.com

a blood condition in which the bicarbonate concentration is below normal. From New Latin, dating back to 18951900; see origin at acid , -osis Dictionary.com UnabridgedBased on the Random House Unabridged Dictionary, Random House, Inc. 2018 Evidently the acidosis fad is to be overworked as was the old uric acid diathesis, of unsavory memory. The behavior of the fat in the body should be carefully watched and the amount reduced at the first evidence of acidosis. When acidosis becomes extreme, the diabetic patient is apt at any time to succumb to the dreaded diabetic coma. Acidosis is a form of intoxication due to the retention of these toxic acids in the body. British Dictionary definitions for acidosis a condition characterized by an abnormal increase in the acidity of the blood and extracellular fluids Derived Formsacidotic (sdtk), adjective Collins English Dictionary - Complete & Unabridged 2012 Digital Edition William Collins Sons & Co. Ltd. 1979, 1986 HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012 An abnormal increase in the acidity of body fluids, caused either by accumulation of acids or by depletion of bicarbonates. The American Heritage Stedman's Medical Dictionary Copyright 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company. Continue reading >>

26.5 Disorders Of Acid-base Balance

26.5 Disorders Of Acid-base Balance

Chapter 26. Fluid, Electrolyte, and Acid-Base Balance By the end of this section, you will be able to: Identify the three blood variables considered when making a diagnosis of acidosis or alkalosis Identify the source of compensation for blood pH problems of a respiratory origin Identify the source of compensation for blood pH problems of a metabolic/renal origin Normal arterial blood pH is restricted to a very narrow range of 7.35 to 7.45. A person who has a blood pH below 7.35 is considered to be in acidosis (actually, physiological acidosis, because blood is not truly acidic until its pH drops below 7), and a continuous blood pH below 7.0 can be fatal. Acidosis has several symptoms, including headache and confusion, and the individual can become lethargic and easily fatigued ( Figure 1 ). A person who has a blood pH above 7.45 is considered to be in alkalosis, and a pH above 7.8 is fatal. Some symptoms of alkalosis include cognitive impairment (which can progress to unconsciousness), tingling or numbness in the extremities, muscle twitching and spasm, and nausea and vomiting. Both acidosis and alkalosis can be caused by either metabolic or respiratory disorders. As discussed earlier in this chapter, the concentration of carbonic acid in the blood is dependent on the level of CO2 in the body and the amount of CO2 gas exhaled through the lungs. Thus, the respiratory contribution to acid-base balance is usually discussed in terms of CO2 (rather than of carbonic acid). Remember that a molecule of carbonic acid is lost for every molecule of CO2 exhaled, and a molecule of carbonic acid is formed for every molecule of CO2 retained. Figure 1. Symptoms of Acidosis and Alkalosis. Symptoms of acidosis affect several organ systems. Both acidosis and alkalosis can be diagnosed u Continue reading >>

Acidosis

Acidosis

Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids). Alkalosis is a condition in which the body fluids have excess base (alkali). This is the opposite of excess acid (acidosis). The kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory or metabolic acidosis . Respiratory acidosis is a condition that occurs when the lungs cannot remove all of the carbon dioxide the body produces. This causes body fluids, e... Metabolic acidosis is a condition in which there is too much acid in the body fluids. Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused when the body is unable to remove enough carbon dioxide through breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include: Kyphosis is a curving of the spine that causes a bowing or rounding of the back. This leads to a hunchback or slouching posture. Metabolic acidosis develops when too much acid is produced in the body. It can also occur when the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes . Diabetic ketoacidosis (DKA) is a life-threatening problem that affects people with diabetes. It occurs when the body starts breaking down fat at a r... Diabetes is a chronic disease Continue reading >>

Definition Of Acidosis In Physiology.

Definition Of Acidosis In Physiology.

Once oxygenation is restored, the acidosis clears quickly. When metabolic acidosis is severe and can no longer be compensated for adequately by the lungs, neutralizing the acidosis with infusions of bicarbonate may be required. One key to distinguish between respiratory and metabolic acidosis is that in respiratory acidosis, the CO2 is increased while the bicarbonate is either normal (uncompensated) or increased (compensated). Compensation occurs if respiratory acidosis is present, and a chronic phase is entered with partial buffering of the acidosis through renal bicarbonate retention. General symptoms of acidosis are described in relation to their location on the body. An excess of acid is called acidosis and an excess in bases is called alkalosis . The phrase "mixed acidosis," for example, refers to metabolic acidosis in conjunction with respiratory acidosis. Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. Differentiate among the acid-base disorders: metabolic acidosis, metabolic alkalosis, respiratory acidosis, and respiratory alkalosis An excess of acid is called acidosis and an excess in bases is called alkalosis . The phrase "mixed acidosis," for example, refers to metabolic acidosis in conjunction with respiratory acidosis. Respiratory acidosis is a medical condition in which decreased ventilation (hypoventilation) causes increased blood carbon dioxide concentration and decreased pH (a condition generally called acidosis). Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. When the blood becomes acidic, respiratory acidosis occurs, which can cause tissue damage if too severe. Acidosis can be caused by hypoventilation (too little breathing), which reduces the removal rate of carbon dioxide, causing it Continue reading >>

Abg Analysis Article

Abg Analysis Article

the"6 Easy Steps to ABG Analysis" were developed to provide nurses with what? an accurate and systematic method of easily interpreting arterial blood gases 5. Does the CO2 or the HCO3 go the opposite direction of the ph? 6. Are the pO2 and the O2 saturation normal? Normal blood pH is 7.4, plus or minus 0.05, forming the range 7.35 to 7.45. If blood pH falls below 7.35 it is acidic. If blood pH rises above 7.45, it is alkalotic. If it falls in the normal range, label what side of 7.4 it falls on. Lower than 7.4 is normal/acidotic, and higher than 7.4 is normal/alkalotic. Label it. Normal pCO2 levels are 35-45 mmHg. Below 35 is alkalotic and above 45 is acidic. Label it. A Normal HCO3 level is 22-26 mEq/L. If below 22 then pt is acidic. If the HCO3is above 26, the patient is alkalotic. Label it. Step 4: Match the CO2 or the HCO3 with the pH Next match either the pCO2 or the HCO3 with the pH to determine the acid-base disorder. For example, if the pH is acidotic, the CO2 is acidotic, then the acid-base disturbance is being caused by the respiratory system = respiratory acidosis. If the pH is alkalotic and the HCO3 is alkalotic the acid-base disturbance is being caused by metabolic (renal) system = metabolic acidosis. Step 5: Does the CO2 or the HCO3 go the opposite direction of the pH? If so then there is compensation by that system. For example, if the pH is acidotic, the CO2 is acidotic, ash the HCO3 is alkalotic. The CO2 matches the pH making the primary acid-base disorder repiratory acidosis. The HCO3 is opposite of the pH and would be evidence of compensation of the metabolic system Step 6: Analyze the pO2 and the O2 saturation If they are below normal there is evidence of hypoxemia -The CO2 is the respiratory component of the ABG, and if it is low and the pH is high Continue reading >>

Acidosis

Acidosis

The kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory or metabolic acidosis. Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused when the body is unable to remove enough carbon dioxide through breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include: Chest deformities, such as kyphosis Chest injuries Chest muscle weakness Chronic lung disease Overuse of sedative drugs Metabolic acidosis develops when too much acid is produced in the body. It can also occur when the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes. Hyperchloremic acidosis is caused by the loss of too much sodium bicarbonate from the body, which can happen with severe diarrhea. Poisoning by aspirin, ethylene glycol (found in antifreeze), or methanol Lactic acidosis is a buildup of lactic acid. Lactic acid is mainly produced in muscle cells and red blood cells. It forms when the body breaks down carbohydrates to use for energy when oxygen levels are low. This can be caused by: Cancer Drinking too much alcohol Exercising vigorously for a very long time Liver failure Low blood sugar (hypoglycemia) Medications, such as salicylates MELAS (a very rare genetic mitochondrial disorder that affects energy production) Prolonged lack of oxygen from shock, heart failure, or seve Continue reading >>

Metabolic Acidosis

Metabolic Acidosis

Metabolic acidosis is a condition that occurs when the body produces excessive quantities of acid or when the kidneys are not removing enough acid from the body. If unchecked, metabolic acidosis leads to acidemia, i.e., blood pH is low (less than 7.35) due to increased production of hydrogen ions by the body or the inability of the body to form bicarbonate (HCO3−) in the kidney. Its causes are diverse, and its consequences can be serious, including coma and death. Together with respiratory acidosis, it is one of the two general causes of acidemia. Terminology : Acidosis refers to a process that causes a low pH in blood and tissues. Acidemia refers specifically to a low pH in the blood. In most cases, acidosis occurs first for reasons explained below. Free hydrogen ions then diffuse into the blood, lowering the pH. Arterial blood gas analysis detects acidemia (pH lower than 7.35). When acidemia is present, acidosis is presumed. Signs and symptoms[edit] Symptoms are not specific, and diagnosis can be difficult unless the patient presents with clear indications for arterial blood gas sampling. Symptoms may include chest pain, palpitations, headache, altered mental status such as severe anxiety due to hypoxia, decreased visual acuity, nausea, vomiting, abdominal pain, altered appetite and weight gain, muscle weakness, bone pain, and joint pain. Those in metabolic acidosis may exhibit deep, rapid breathing called Kussmaul respirations which is classically associated with diabetic ketoacidosis. Rapid deep breaths increase the amount of carbon dioxide exhaled, thus lowering the serum carbon dioxide levels, resulting in some degree of compensation. Overcompensation via respiratory alkalosis to form an alkalemia does not occur. Extreme acidemia leads to neurological and cardia Continue reading >>

Alkalosis

Alkalosis

Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia. Related to alkalosis: metabolic acidosis, metabolic alkalosis, respiratory alkalosis al·ka·lo·sis (al-kă-lō'sis), Do not confuse this word with ankylosis. A state characterized by a decrease in the hydrogen ion concentration of arterial blood below the normal level, 40 nmol/L, or pH over 7.4. The condition may be caused by an increase in the concentration of alkaline compounds, or by a decrease in the concentration of acidic compounds or carbon dioxide. alkalosis /al·ka·lo·sis/ (al″kah-lo´sis) a pathologic condition due to accumulation of base in, or loss of acid from, the body. Cf. acidosis. alkalot´ic altitude alkalosis increased alkalinity in blood and tissues due to exposure to high altitudes. compensated alkalosis a form in which compensatory mechanisms have returned the pH toward normal. hypochloremic alkalosis metabolic alkalosis marked by hypochloremia together with hyponatremia and hypokalemia, resulting from the loss of sodium chloride and hydrochloric acid due to prolonged vomiting. metabolic alkalosis a disturbance in which the acid-base status shifts toward the alkaline side because of retention of base or loss of noncarbonic, or fixed (nonvolatile), acids. respiratory alkalosis a state due to excess loss of carbon dioxide from the body, usually as a result of hyperventilation. alkalosis (ăl′kə-lō′sĭs) n. 1. Abnormally high alkalinity of the blood and body tissues caused by an excess of bicarbonates, as from an increase in alkali intake, or by or a deficiency of acids other than carbonic acid, as from vomiting. Also called metabolic alkalosis. 2. Abnormally high alkalinity of the blood and body tissues caused by a deficiency of carbon dioxide due to hyperventilation. Also cal Continue reading >>

Acidosis Has Opposite Effects On Neuronal Survival During Hypoxia And Reoxygenation

Acidosis Has Opposite Effects On Neuronal Survival During Hypoxia And Reoxygenation

Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation Address correspondence and reprint requests to Runar Almaas, Department of Pediatric Research, Rikshospitalet, N0027 Oslo, Norway. Email: [email protected] Please review our Terms and Conditions of Use and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use. Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. To study the effect of extracellular acidosis on apoptosis and necrosis during ischemia and reoxygenation, we exposed human postmitotic NT2N neurones to oxygen and glucose deprivation (OGD) followed by reoxygenation. In some experiments, pH of the cell medium was lowered to 5.9 during either OGD or reoxygenation or both. Staurosporine, used as a positive control for apoptosis, caused Poly(ADPribose)polymerase (PARP) cleavage and nuclear fragmentation, but no PARP cleavage and little fragmentation were seen after OGD. Low molecular weight DNA fragments were found after staurosporine treatment, but not after OGD. No protective effect of caspase inhibitors was seen after 3 h of OGD and 21 h of reoxygenation, but after 45 h of reoxygenation caspase inhibition induced a modest improvement in 3(4,5dimethylthiazol2yl)2,5diphenyltetrazolium bromide (MTT) cleavage. While acidosis during OGD accompanied by neutral medium during reoxygenation protected the neurones (MTT: 228 117% of neutral medium, p < 0.001), acidosis during reoxygenation only was detrimental (MTT: 38 25%, p < 0.01). We conclude that apoptotic mechanisms play a minor role after OGD in NT2N neurones. The effect of acidosis on neuronal survival depends on the timing of acidosis, as acidosis w Continue reading >>

How To Read Abgs Like A Boss: Master Acid-base Disorders!

How To Read Abgs Like A Boss: Master Acid-base Disorders!

How to Read ABGs Like a Boss: Master Acid-Base Disorders! Acid-base imbalances are an important concept of nursing practice, not to mention something youll need to learn in school. Teachers have different ways to teach students how to interpret ABGs, but heres my preferred method. ABG stands for Arterial Blood Gas. You will need to stick an artery to get ABG values. ABGs will include a few different lab values including pH, pCO2, and HCO3. Now that we have the normal values, we first will need to decide if the patient has some kind of acidosis versus alkalosis. Acidosis is defined as a pH lower than 7.35. The lower the pH, the more acidic the solution. Alkalosis is defined as a pH higher than 7.45. The higher the pH, the more alkalotic the solution. Question: Ms. Jones has a pH of 7.3. Does she have some sort of acidosis or alkalosis? Question: Ms. Jones has a pH of 7.5. Does she have some sort of acidosis or alkalosis? Ok great, you know how to tell if the patient is in acidosis or alkalosis, but now we need to know what has caused this change in pH. You have two causes: respiratory or metabolic. Respiratory concerns the fluctuation of the lab carbon dioxide (CO2). This should be easy to remember since we exhale carbon dioxide when we breathe out air. Metabolic concerns the fluctuations of the lab bicarbonate (HCO3). How will I know which is causing the problem? One of my favorite mnemonics is R.O.M.E. That stands for Respiratory Opposite, Metabolic Equal. How do I use this mnemonic? First, you need to determine the direction of your lab imbalances. Determine if pH is up or down from normal like we just learned. Draw an arrow pointing up or down near your pH value. Determine if the respiratory lab (CO2) is up or down from normal. Draw an arrow pointing up or down near Continue reading >>

Acidosis | Find Health Information | Firstlight Health System

Acidosis | Find Health Information | Firstlight Health System

The kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory or metabolic acidosis . Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused when the body is unable to remove enough carbon dioxide through breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include: Metabolic acidosis develops when too much acid is produced in the body. It can also occur when the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes . Hyperchloremic acidosis is caused by the loss of too much sodium bicarbonate from the body, which can happen with severe diarrhea. Sepsis -- severe illness due to infection with bacteria or other germs Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids). The health care provider will perform a physical examination and ask about your symptoms. Laboratory tests that may be ordered include: Electrolytes test, such as a basic metabolic panel to confirm acidosis and show whether it is metabolic or respiratory acidosis. Other tests may be needed to determine the cause of the acidosis. Acidosis can be dangerous if untreated. Many cases respond well to treatment. Complications depend on the specific type of acidosis. Prevent Continue reading >>

Disorders Of Acid-base Balance

Disorders Of Acid-base Balance

Module 10: Fluid, Electrolyte, and Acid-Base Balance By the end of this section, you will be able to: Identify the three blood variables considered when making a diagnosis of acidosis or alkalosis Identify the source of compensation for blood pH problems of a respiratory origin Identify the source of compensation for blood pH problems of a metabolic/renal origin Normal arterial blood pH is restricted to a very narrow range of 7.35 to 7.45. A person who has a blood pH below 7.35 is considered to be in acidosis (actually, physiological acidosis, because blood is not truly acidic until its pH drops below 7), and a continuous blood pH below 7.0 can be fatal. Acidosis has several symptoms, including headache and confusion, and the individual can become lethargic and easily fatigued. A person who has a blood pH above 7.45 is considered to be in alkalosis, and a pH above 7.8 is fatal. Some symptoms of alkalosis include cognitive impairment (which can progress to unconsciousness), tingling or numbness in the extremities, muscle twitching and spasm, and nausea and vomiting. Both acidosis and alkalosis can be caused by either metabolic or respiratory disorders. As discussed earlier in this chapter, the concentration of carbonic acid in the blood is dependent on the level of CO2 in the body and the amount of CO2 gas exhaled through the lungs. Thus, the respiratory contribution to acid-base balance is usually discussed in terms of CO2 (rather than of carbonic acid). Remember that a molecule of carbonic acid is lost for every molecule of CO2 exhaled, and a molecule of carbonic acid is formed for every molecule of CO2 retained. Figure 1. Symptoms of acidosis affect several organ systems. Both acidosis and alkalosis can be diagnosed using a blood test. Metabolic Acidosis: Primary Bic Continue reading >>

Metabolic Acidosis

Metabolic Acidosis

What is metabolic acidosis? The buildup of acid in the body due to kidney disease or kidney failure is called metabolic acidosis. When your body fluids contain too much acid, it means that your body is either not getting rid of enough acid, is making too much acid, or cannot balance the acid in your body. What causes metabolic acidosis? Healthy kidneys have many jobs. One of these jobs is to keep the right balance of acids in the body. The kidneys do this by removing acid from the body through urine. Metabolic acidosis is caused by a build-up of too many acids in the blood. This happens when your kidneys are unable to adequately remove the acid from your blood. What are the signs and symptoms? Not everyone will have signs or symptoms. However, you may experience: Long and deep breaths Fast heartbeat Headache and/or confusion Weakness Feeling very tired Vomiting and/or feeling sick to your stomach (nausea) Loss of appetite If you experience any of these, it is important to let your healthcare provider know immediately. What are the complications of metabolic acidosis if I have kidney disease or kidney failure? Increased bone loss (osteoporosis): Metabolic acidosis can lead to a loss of bone in your body. This can lead to a higher chance of fractures in important bones like your hips or backbone. Progression of kidney disease: Metabolic acidosis can make your kidney disease worse. Exactly how this happens is not clear. As acid builds up, kidney function lowers; and as kidney function lowers, acid builds up. This can lead to the progression of kidney disease. Muscle loss: Albumin is an important protein in your body that helps build and keep muscles healthy. Metabolic acidosis lowers the amount of albumin created in your body, and leads to muscle loss, or what is called Continue reading >>

Acidosis

Acidosis

Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids). Alkalosis is a condition in which the body fluids have excess base (alkali). This is the opposite of excess acid (acidosis). The kidneys and lungs maintain the balance (proper pH level) of chemicals called acids and bases in the body. Acidosis occurs when acid builds up or when bicarbonate (a base) is lost. Acidosis is classified as either respiratory or metabolic acidosis . Respiratory acidosis is a condition that occurs when the lungs cannot remove all of the carbon dioxide the body produces. This causes body fluids, e... Metabolic acidosis is a condition in which there is too much acid in the body fluids. Respiratory acidosis develops when there is too much carbon dioxide (an acid) in the body. This type of acidosis is usually caused when the body is unable to remove enough carbon dioxide through breathing. Other names for respiratory acidosis are hypercapnic acidosis and carbon dioxide acidosis. Causes of respiratory acidosis include: Kyphosis is a curving of the spine that causes a bowing or rounding of the back. This leads to a hunchback or slouching posture. Metabolic acidosis develops when too much acid is produced in the body. It can also occur when the kidneys cannot remove enough acid from the body. There are several types of metabolic acidosis: Diabetic acidosis (also called diabetic ketoacidosis and DKA) develops when substances called ketone bodies (which are acidic) build up during uncontrolled diabetes . Diabetic ketoacidosis is a life-threatening problem that affects people with diabetes. It occurs when the body cannot use sugar (glucose) as a fuel ... Diabetes is a chronic disease Continue reading >>

Acute Respiratory Alkalosis And Acidosis And Rabbit Intestinal Ion Transport In Vivo.

Acute Respiratory Alkalosis And Acidosis And Rabbit Intestinal Ion Transport In Vivo.

Acute respiratory alkalosis and acidosis and rabbit intestinal ion transport in vivo. The effects of acute respiratory alkalosis and acidosis on electrolyte transport in the rabbit ileum, colon, and gallbladder were studied. During in situ perfusion, anesthetized animals were ventilated with 0, 3, or 8% CO2 gas, creating states of alkalosis (pH 7.49 +/- 0.01, PCO2 = 27.0 +/- 0.9 mmHg, HCO3 = 21.7 mM), normocapnia (pH 7.38 +/- 0.02, PCO2 = 41.3 +/- 1.1 mmHg, HCO3 = 25.9 +/- 0.4 mM), and acidosis (pH 7.21 +/- 0.01, PCO2 = 66.3 +/- 1.3 mmHg, HCO3 = 28.1 +/- 0.8 mM). In the ileum alkalosis decreased the net absorption of water (-36%), sodium (-44%), and chloride (-27%), whereas acidosis had the opposite effect on water (+69%), sodium (+98%), and chloride (+32%) absorption and reduced bicarbonate secretion. Small changes in net potassium absorption occurred in the direction of water movement. There was no effect on the ileal transmural potential difference (PD). The colon and gallbladder did not respond to the acid-base disorders with changes in electrolyte transport or PD. These results suggest that systemic pH and/or PCO2 affect an electroneutral sodium chloride absorptive process in the rabbit ileum. The simple presence of this absorptive process in the gallbladder was not a sufficient basis for this organ to respond to alterations in systemic pH. Continue reading >>

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