What Is The Most Common Cause Of Metabolic Acidosis?

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A Rare Cause Of Metabolic (lactic) Acidosis Highlighted

A rare cause of metabolic (lactic) acidosis highlighted Summarized from Giacalone M, Martinelli R, Abramo A et al. Rapid reversal of severe lactic acidosis after thiamine administration in critically ill adults: a report of three cases. Nutrition in Clinical Practice 2015; 30: 104-10Salvatori G, Mondi V, Piersigelli F et al. Thiamine deficiency in a developed country: acute lactic acidosis in two neonates due to unsupplemented parenteral nutrition. J Parenter Enteral Nutr 2015. Published online Jan 2015 ahead of print publication. Available at: Lactic acidosis, the most common kind of metabolic acidosis, is characterized by reduced blood pH (usually <7.25) in association with marked increase in blood lactate (usually >5.0 mmol/L). Lactic acidosis has many possible causes but two broad etiological classes have been defined: type A (hypoxic) lactic acidosis and type B (non-hypoxic) lactic acidosis. Of the two, type A lactic acidosis, i.e. lactic acidosis arising from reduced tissue perfusion and/or severe hypoxemia, is the more common. In the absence of an adequate oxygen supply, tissue cells must depend on less efficient anaerobic metabolism of glucose for its energy production, an Continue reading >>

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  1. [deleted]


    Sweet, Walgreens has Ketostix on sale! Wait...what? (i.imgur.com)

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  3. Wyrd_5

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