What Is The Compensation For Respiratory Acidosis?

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Respiratory Acidosis

DEFINITION Respiratory acidosis = a primary acid-base disorder in which arterial pCO2 rises to an abnormally high level. PATHOPHYSIOLOGY arterial pCO2 is normally maintained at a level of about 40 mmHg by a balance between production of CO2 by the body and its removal by alveolar ventilation. PaCO2 is proportional to VCO2/VA VCO2 = CO2 production by the body VA = alveolar ventilation an increase in arterial pCO2 can occur by one of three possible mechanisms: presence of excess CO2 in the inspired gas decreased alveolar ventilation increased production of CO2 by the body CAUSES Inadequate Alveolar Ventilation central respiratory depression drug depression of respiratory centre (eg by opiates, sedatives, anaesthetics) neuromuscular disorders lung or chest wall defects airway obstruction inadequate mechanical ventilation Over-production of CO2 -> hypercatabolic disorders Malignant hyperthermia Thyroid storm Phaeochromocytoma Early sepsis Liver failure Increased Intake of Carbon Dioxide Rebreathing of CO2-containing expired gas Addition of CO2 to inspired gas Insufflation of CO2 into body cavity (eg for laparoscopic surgery) EFFECTS CO2 is lipid soluble -> depressing effects on intrace Continue reading >>

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Popular Questions

  1. goedegeit

    Since I've started on Keto, I've been getting some bad stabbing pains in my right shoulder blade. I'm worried that it could be gall stones or something.
    I've been on keto for just over a month now and lost over half a stone, and I'm happy with what I'm eating, but if this is giving me gallstones I'm off it faster than a dog on a forbidden chair when their owner comes in.

  2. sassytaters

    IANAD, but from what I've read around here, switching from a low-fat diet to a high-fat can get the gallbladder squeezing and contracting and doing its job better, which can dislodge any stones that are already in there (likely caused by the high-carb diet, where it didn't have to do as much). When I first tried Atkins in 2012, I had awful gallbladder attacks after eating fatty stuff like pulled pork. Unfortunately I used it as one of many excuses to fall off the wagon, and it took me 2 years to find my way back to low-carb eating. I've had 0 gallbladder trouble this time (I have been keto for two years), but I have no idea what the difference would be or if maybe all the stones I had just worked themselves loose or what.
    Here's a link that might help:

  3. Kye7

    Thanks for the link and great post.
    I dramatically changed my diet yesterday, starting keto.
    I today (1 day later) have a deep pain in my right shoulder, and I think this is the cause. I am extremely healthy, work out 5 days a week, but never had a pain like this. It only hurts at about a 3/10, but enough to be uncomfortable.
    What can I do to make it stop? I obviously made the transition much too quickly. Have I done permanent damage to my body? Thanks in advance for your reply.

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