
How To Use Ketosis For Hunger Suppression
Most diets aren’t sustainable. Anyone who’s lost weight on a diet initially but gained the weight back afterwards will know this. That’s because most diets leave you feeling hungry and unsatisfied much of the time. This is where the ketogenic diet provides a nice advantage that can make it more effective for weight loss than other eating plans: it helps suppress hunger and appetite. If you’re wondering how to use ketosis for hunger suppression, this article will walk you through how exactly this can be done and why it’s a better method than other diets. Ketosis Vs Traditional Dieting Ketosis is achieved through either intermittent fasting, eating high-fat and very-low-carb, or a combination of both. It’s also importatnt to note that ketosis and intermittent fasting aren’t interchangeable. While the ketogenic diet has a structure to follow, there are some big differences between eating for ketosis and following a traditional diet plan. Let’s start by talking about the traditional practice of calorie counting for weight loss and why it alone is ineffective. Why Calorie Counting is Impractical Short-term weight loss is pretty easy for most people. Any of us can follow a strict diet for a short period of time to shed pounds, but for most dieters that weight gradually comes back over time — and often leaves them weighing more than they did to begin with. The typical calorie-restrictive diet leaves us with hunger pangs and food cravings, not taking nutrition or satiety into account. This is ineffective because: The body doesn’t process all calories the same. Quality matters. Many traditional diet foods, especially packaged foods, are not healthy for us or filling. The focus becomes too much about how many calories you’re eating and not enough about what Continue reading >>

What Is Ketosis, And Is It Healthy?
Ketosis is a natural metabolic state. It involves the body producing ketone bodies out of fat, and using them for energy instead of carbs. You can get into ketosis by following a very low-carb, high-fat ketogenic diet (1). In addition to fast weight loss, ketosis may have several health benefits, such as reduced seizures in epileptic children (2). Ketosis is quite complex, but this article explains what it is and how it can benefit you. Ketosis is a metabolic state in which fat provides most of the fuel for the body. It occurs when there is limited access to glucose (blood sugar), which is the preferred fuel source for many cells in the body. Ketosis is most often associated with ketogenic and very low-carb diets. It also happens during pregnancy, infancy, fasting and starvation (3, 4, 5, 6). To go into ketosis, people generally need to eat fewer than 50 grams of carbs per day and sometimes as little as 20 grams per day. This requires removing certain food items from your diet, such as grains, candy and sugary soft drinks. You also have to cut back on legumes, potatoes and fruit. When eating a very low-carb diet, levels of the hormone insulin go down and fatty acids are released from body fat stores in large amounts. Many of these fatty acids are transferred to the liver, where they are oxidized and turned into ketones (or ketone bodies). These molecules can provide energy for the body. Unlike fatty acids, ketones can cross the blood-brain barrier and provide energy for the brain in the absence of glucose. Ketosis is a metabolic state where ketones become the main sources of energy for the body and brain. This happens when carb intake and insulin levels are very low. It's a common misunderstanding that the brain doesn't function without dietary carbs. It's true that glu Continue reading >>

Metabolism And Ketosis
Dr. Eades, If the body tends to resort to gluconeogenesis for glucose during a short-term carbohydrate deficit, are those who inconsistently reduce carb intake only messing things up by not effecting full blown ketosis? If the body will still prefer glucose as main energy source unless forced otherwise for at least a few days, is it absolutely necessary to completely transform metabolism for minimal muscle loss? Also, if alcohol is broken down into ketones and acetaldehyde, technically couldn’t you continue to drink during your diet or would the resulting gluconeogenesis inhibition from alcohol lead to blood glucose problems on top of the ketotic metabolism? Would your liver ever just be overwhelmed by all that action? I’m still in high school so hypothetical, of course haha… Sorry, lots of questions but I’m always so curious. Thank you so much for taking the time to inform the public. You’re my hero! P.S. Random question…what’s the difference between beta and gamma hydroxybutyric acids? It’s crazy how simple orientation can be the difference between a ketone and date rape drug…biochem is so cool! P.P.S. You should definitely post the details of that inner mitochondrial membrane transport. I’m curious how much energy expenditure we’re talkin there.. Keep doin your thing! Your Fan, Trey No, I don’t think people are messing up if they don’t get into full-blown ketosis. For short term low-carb dieting, the body turns to glycogen. Gluconeogenesis kicks in fairly quickly, though, and uses dietary protein – assuming there is plenty – before turning to muscle tissue for glucose substrate. And you have the Cori cycle kicking in and all sorts of things to spare muscle, so I wouldn’t worry about it. And you can continue to drink while low-carbing. Continue reading >>

Starvation Ketoacidosis: Treatment Pitfalls
Dear Editor, Yeow et al.1 describe a case of non-diabetic euglycaemic acidosis resulting from post op dysphagia and poor intake of approximately six weeks duration. We have seen a similar case of ‘starvation ketoacidosis’ in a patient undergoing percutaneous endoscopic gastrostomy feeding tube replacement. We think that intravenous (IV) glucose should be the initial treatment, with the addition of insulin only if required. The correspondence from Frise and Mackillop2 states this strategy is effective for treating ketoacidosis in pregnancy; however, there are also some other pitfalls in treatment of starvation ketoacidosis which must be considered, and some overlap with alcoholic ketoacidosis. Unlike patients with diabetic ketoacidosis, patients with starvation ketosis release insulin when carbohydrate is administered. They are also producing high levels of glucose elevating hormones such as glucagon and have depleted glycogen stores. These hormones cause the lipolysis which helps generate ketones for fuel. The addition of exogenous insulin in this state risks hypoglycaemia. Once provided with adequate carbohydrate the insulin levels will rise and counter-regulatory hormone levels will fall, resolving the ketosis. Alcoholics are another group prone to ketosis (alcoholic ketoacidosis (AKA)) and are particularly prone to hypoglycaemia; administration of insulin to those patients would have to be with caution and literature3 on AKA reports resolution without insulin administration, although there is little evidence outside of case reports. Starved patients and alcoholics are also both at risk of thiamine deficiency. Depletion of body thiamine stores can occur within four weeks. It is important to consider this, as administration of IV glucose in thiamine deficiency can Continue reading >>

What Is Starvation Ketosis?
Starvation ketosis is a metabolic state in humans and many animals in which the body breaks down fat and produces acids known as ketones, then uses these as a primary energy source. The “starvation” part of the name owes to the fact that, in most cases, people only use ketones for energy when they aren’t getting adequate glucose from food. The body typically converts carbohydrates to glucose as a main source of energy, but once the liver has used all of its stored glucose it begins to metabolize fatty acids, forming ketone bodies. Malnutrition and fasting are two of the most common causes, but it can also be the result of conditions like diabetes, alcoholism, and a low carbohydrate diet. People sometimes intentionally trigger this state as a means of burning fat to lose weight, but whether this practice is safe or even advisable is widely disputed in the medical community. Ketones are capable of supplying energy to the body, but an abnormally high level can cause a number of problems, including organ damage, coma, and even death. Understanding Ketones The liver typically makes ketones in response to some sort of energy crisis in the body. People generally get the majority of their energy by synthesizing glucose, which is a sugar molecule found in carbohydrates like bread and grain products. When people aren’t getting enough glucose, the liver begins creating ketones that the body uses in combination with any fat stores it has on hand. Ketones in many ways prevent the body from robbing muscles of their core proteins. Starvation ketosis happens when these become the body’s primary source of energy. The condition can usually be identified by looking for excesses. The body gets rid of unneeded supplies by spilling them out through exhalations, urine, and sweat. Wh Continue reading >>

What Is Ketosis?
"Ketosis" is a word you'll probably see when you're looking for information on diabetes or weight loss. Is it a good thing or a bad thing? That depends. Ketosis is a normal metabolic process, something your body does to keep working. When it doesn't have enough carbohydrates from food for your cells to burn for energy, it burns fat instead. As part of this process, it makes ketones. If you're healthy and eating a balanced diet, your body controls how much fat it burns, and you don't normally make or use ketones. But when you cut way back on your calories or carbs, your body will switch to ketosis for energy. It can also happen after exercising for a long time and during pregnancy. For people with uncontrolled diabetes, ketosis is a sign of not using enough insulin. Ketosis can become dangerous when ketones build up. High levels lead to dehydration and change the chemical balance of your blood. Ketosis is a popular weight loss strategy. Low-carb eating plans include the first part of the Atkins diet and the Paleo diet, which stress proteins for fueling your body. In addition to helping you burn fat, ketosis can make you feel less hungry. It also helps you maintain muscle. For healthy people who don't have diabetes and aren't pregnant, ketosis usually kicks in after 3 or 4 days of eating less than 50 grams of carbohydrates per day. That's about 3 slices of bread, a cup of low-fat fruit yogurt, or two small bananas. You can start ketosis by fasting, too. Doctors may put children who have epilepsy on a ketogenic diet, a special high-fat, very low-carb and protein plan, because it might help prevent seizures. Adults with epilepsy sometimes eat modified Atkins diets. Some research suggests that ketogenic diets might help lower your risk of heart disease. Other studies show sp Continue reading >>

Ketoacidosis
GENERAL ketoacidosis is a high anion gap metabolic acidosis due to an excessive blood concentration of ketone bodies (keto-anions). ketone bodies (acetoacetate, beta-hydroxybutyrate, acetone) are released into the blood from the liver when hepatic lipid metabolism has changed to a state of increased ketogenesis. a relative or absolute insulin deficiency is present in all cases. CAUSES The three major types of ketosis are: (i) Starvation ketosis (ii) Alcoholic ketoacidosis (iii) Diabetic ketoacidosis STARVATION KETOSIS when hepatic glycogen stores are exhausted (eg after 12-24 hours of total fasting), the liver produces ketones to provide an energy substrate for peripheral tissues. ketoacidosis can appear after an overnight fast but it typically requires 3 to 14 days of starvation to reach maximal severity. typical keto-anion levels are only 1 to 2 mmol/l and this will usually not alter the anion gap. the acidosis even with quite prolonged fasting is only ever of mild to moderate severity with keto-anion levels up to a maximum of 3 to 5 mmol/l and plasma pH down to 7.3. ketone bodies also stimulate some insulin release from the islets. patients are usually not diabetic. ALCOHOLIC KETOSIS Presentation a chronic alcoholic who has a binge, then stops drinking and has little or no oral food intake for a few days (ethanol and fasting) volume depletion is common and this can result in increased levels of counter regulatory hormones (eg glucagon) levels of free fatty acids (FFA) can be high (eg up to 3.5mM) providing plenty of substrate for the altered hepatic lipid metabolism to produce plenty of ketoanions GI symptoms are common (eg nausea, vomiting, abdominal pain, haematemesis, melaena) acidaemia may be severe (eg pH down to 7.0) plasma glucose may be depressed or normal or Continue reading >>

Ketosis Explained – For Weight Loss, Health Or Performance
Get Started Ketosis is a natural state for the body, when it is almost completely fueled by fat. This is normal during fasting, or when on a strict low-carb diet. Ketosis has many potential benefits, but there are also side effects. In type 1 diabetes and certain other rare situations excessive ketosis can even become dangerous. On this page you can learn all about how to harness the benefits of ketosis, while avoiding any problems. It all starts with understanding what ketosis is. Choose a section, or keep reading below for all of them. Ketosis ExplainedKetosis Explained BenefitsBenefits How to Get Into KetosisHow to Get Into Ketosis Ketosis ExplainedSymptoms & How to Know You’re In Ketosis Side Effects, Fears & Potential DangersSide Effects, Fears & Potential Dangers How to Reach Optimal KetosisHow to Reach Optimal Ketosis ketones Ketosis Explained The “keto” in the word ketosis comes from the fact that it makes the body produce small fuel molecules called “ketones”.1 This is an alternative fuel for the body, used when blood sugar (glucose) is in short supply. Ketones are produced if you eat very few carbs (that are broken down into blood sugar) and only moderate amounts of protein (excess protein can be converted to blood sugar). Ketones are produced in the liver, from fat. They are then consumed as fuel in the body, including by the brain. This is important as the brain is a hungry organ that consumes lots of energy every day,2 and it can’t run on fat directly. It can only run on glucose… or ketones. Maximizing fat burning On a ketogenic diet your entire body switches its fuel supply to run almost entirely on fat. Insulin levels become very low and fat burning increases dramatically. It becomes easy to access your fat stores to burn them off. This is o Continue reading >>
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Starvation Ketoacidosis As A Cause Of Unexplained Metabolic Acidosis In The Perioperative Period
Go to: Abstract Patient: Female, 24 Final Diagnosis: Starvation ketoacidosis Symptoms: None Medication: — Clinical Procedure: Lumbar laminectomy Specialty: Orthopedics and Traumatology Besides providing anesthesia for surgery, the anesthesiologist’s role is to optimize the patient for surgery and for post-surgical recovery. This involves timely identification and treatment of medical comorbidities and abnormal laboratory values that could complicate the patient’s perioperative course. There are several potential causes of anion and non-anion gap metabolic acidosis in surgical patients, most of which could profoundly affect a patient’s surgical outcome. Thus, the presence of an acute acid-base disturbance requires a thorough workup, the results of which will influence the patient’s anesthetic management. An otherwise-healthy 24-year-old female presented for elective spine surgery and was found to have metabolic acidosis, hypotension, and polyuria intraoperatively. Common causes of acute metabolic acidosis were investigated and systematically ruled out, including lactic acidosis, diabetic ketoacidosis, drug-induced ketoacidosis, ingestion of toxic alcohols (e.g., methanol, ethylene glycol), uremia, and acute renal failure. Laboratory workup was remarkable only for elevated serum and urinary ketone levels, believed to be secondary to starvation ketoacidosis. Due to the patient’s unexplained acid-base disturbance, she was kept intubated postoperatively to allow for further workup and management. Starvation ketoacidosis is not widely recognized as a perioperative entity, and it is not well described in the medical literature. Lack of anesthesiologist awareness about this disorder may complicate the differential diagnosis for acute intraoperative metabolic acidosi Continue reading >>

How Ketosis Helps You Lose Weight Through Suppressed Appetite
One of the reasons The Bulletproof Diet with Bulletproof Coffee works so well for people looking to lose weight is that Bulletproof Intermittent Fasting helps your body to more easily enter a state called cyclical ketosis, which is great for a whole bunch of reasons. Ketosis is a cornerstone of becoming Bulletproof; listen to these recent Bulletproof Radio episodes with ketosis experts Jimmy Moore and Dominic D’Agostino to get the scoop on how and why it works. It’s what happens when your body switches to burning fat instead of sugar for energy, and it only happens when you eat almost no carbohydrates, or when you hack it using certain kinds of oils. Many people first stumble upon the idea of ketosis while looking for a weight loss strategy. That can be a major part of it for so many people out there who have tried just about every other diet out there but haven’t seen the results they’d hoped for. But when people experience the mental clarity and focus that ketosis brings, the game changes! This post walks you through one of the most important yet underrated mechanisms that makes ketosis so effective for people who have tried everything else to lose weight and failed to keep it off: appetite suppression. Ketosis works for weight loss in the short term, but that’s not why it’s so amazing. Short term weight loss is easy (I’ve lost at least 200 pounds of short term weight…because it always roared back on with a vengeance so I could lose it again!) When you look at keeping your weight off forever, ketosis provides a level of appetite suppression that is actually liberating. Ketosis helps you literally stop thinking about food all the time. Why Calorie Counting Is So Ineffective One of the reasons old-fashioned, calorie-restricted diets tend to fail is becau Continue reading >>
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Starvation Mode Myth
STARVATION MODE If you are a sugar burner, your muscles rely on glucose for fuel. So if you deprive your body of glucose through fasting or caloric deficit, your body will run out of glucose at some point as it can only store about 2000 calories or so of glucose in your muscles and liver. The body then starts to cannibalize protein to make more sugar to fuel the body. This is what is referred to as “starvation mode”. But, if you are on a well formulated ketogenic diet, you are no longer burning glucose for fuel. You are burning Ketones! WHY INTERMITTENT FASTING WORKS WITH KETO! A ketogenic diet spares protein from being oxidized, which preserves muscle. This is why you do not go into “starvation mode.” Branched-chain amino acids are considered essential because your body can’t make them, so you need to consume them for proper muscle building and repair (as well replenishing red blood cells). What I found so interesting is that BCAA oxidation rates usually rise with exercise, which means you need more if you are an athlete. But in keto-adapted athletes, ketones are burned in place of BCAA. Your muscles will actual go though a change where they reject insulin (and as a result glucose) because they PREFER to burn ketones over glucose. So your muscle energy comes from ketones, not glucose. This can actually cause some people fasting blood sugar levels to temporarily rise when becoming keto adapted (called phsysiological insulin resistance). As your muscles reject glucose your blood levels rise since you muscles are no longer using it for fuel. Critics of low-carb diets claim that you need insulin to grow muscles; however, in a well-designed low-carb, high-fat diet there is less protein oxidation and double the amount of fat oxidation, which leaves your muscles in Continue reading >>

Why Dka & Nutritional Ketosis Are Not The Same
There’s a very common misconception and general misunderstanding around ketones. Specifically, the misunderstandings lie in the areas of: ketones that are produced in low-carb diets of generally less than 50 grams of carbs per day, which is low enough to put a person in a state of “nutritional ketosis” ketones that are produced when a diabetic is in a state of “diabetic ketoacidosis” (DKA) and lastly, there are “starvation ketones” and “illness-induced ketones” The fact is they are very different. DKA is a dangerous state of ketosis that can easily land a diabetic in the hospital and is life-threatening. Meanwhile, “nutritional ketosis” is the result of a nutritional approach that both non-diabetics and diabetics can safely achieve through low-carb nutrition. Diabetic Ketoacidosis vs. Nutritional Ketosis Ryan Attar (soon to be Ryan Attar, ND) helps explain the science and actual human physiology behind these different types of ketone production. Ryan is currently studying to become a Doctor of Naturopathic Medicine in Connecticut and also pursuing a Masters Degree in Human Nutrition. He has interned under the supervision of the very well-known diabetes doc, Dr. Bernstein. Ryan explains: Diabetic Ketoacidosis: “Diabetic Ketoacidosis (DKA), is a very dangerous state where an individual with uncontrolled diabetes is effectively starving due to lack of insulin. Insulin brings glucose into our cells and without it the body switches to ketones. Our brain can function off either glucose or fat and ketones. Ketones are a breakdown of fat and amino acids that can travel through the blood to various tissues to be utilized for fuel.” “In normal individuals, or those with well controlled diabetes, insulin acts to cancel the feedback loop and slow and sto Continue reading >>

What You Should Know About “starvation Mode”
“Starvation mode:” it’s the boogeyman of diets everywhere, but it’s hard to know what to say about it when the people worrying about it can’t agree on a definition! Whether or not any such thing as “starvation mode” actually exists depends on what you mean by the term. What Is “Starvation Mode?” The basic idea of “starvation mode” is that your body can tell when it’s not getting enough calories, assumes there’s a famine going on, and pulls out all the stops to prevent any further weight loss. It’s not controversial at all that weight loss causes metabolic adaptation (more on this below). But the big question is: does starvation mode completely stop weight loss, or just make it increasingly difficult? Can/does it actually cause weight gain? The answers to those questions are the difference between “starvation mode” as scare-tactic nonsense and “starvation mode” as a serious problem. Metabolic (and Other) Adaptation to Weight Loss It’s objectively that if you reduce calories enough to lose weight (whether or not you’re counting them, which is a completely different question), your whole body will adapt in ways that resist weight loss. Body temperature drops (so you can burn fewer calories to keep yourself warm); levels of thyroid hormone drop; levels of other hormones like leptin and ghrelin change. If you want to read all about it, you can do it here. This is a survival mechanism. You can reduce the damage, but it’s impossible to avoid completely, and you can’t cheat it with hot peppers or green tea or anything else. The only way to avoid it is to never reduce calories below the level needed to maintain your weight. The adaptation is not just because calorie restriction causes weight loss, and a smaller body takes less energy t Continue reading >>

How Do I Break The Starvation Mode And Maintain Ketosis?
How do I break the starvation mode and maintain ketosis? How do I break the starvation mode and maintain ketosis? I am a frequent reader of BB.com and have been in the background more or less since the end of 2005. Without a lot of background I am fairly certain my body has dropped my metabolism in response to years of low calorie PSMF'ing with calorie intake on average <1200 a day. After resolving some personal issues I seem to dropping some weight although fairly slow and not even close to my past experience of 2.5 lbs per week over 8 months. I understand after research here that I need to up the calories, weight train and bulk and cut separately. I was 268 around Oct 05 and 249 now and 66". Most of the progress has been in the last two months. But back to my question, if I increase the protein and fat calories will that break the cycle while maintaining ketosis? Will weight training break the cycle, maintain muscle mass and stay in ketosis? Will bike rides three days a week break the cycle? What I am asking is will the body shut down with a low calorie intake regardless of the work performed? I have to stay off carbs, they seemed to be utilized at a rate of 1 lb gained for every 1 lb consumed. I am eating some green veggies, salad, cauliflower and broc**** so I am not competely carb free. This is very frustrating because keto dieting has really never failed to show results until the last 12-18 months. - 2 scrambled eggs and 2 slices of bacon (breakfast) - Cappuccino, dry but with some milk and Spenda - 7 ounces of canned salmon with 1 oz mayo (lunch) - 2 breasts and a thigh from KFC with the skin and batter removed (dinner) I guess it is possible that I am not in starvation mode but just taking in to many calories with to little activity resulting in slow weightloss Continue reading >>

Hunger
Because this has to be said, my shower-thought of the day: I see a lot of people complaining about “hunger” when dieting – “I’m doing a ketogenic diet… why am I hungry? – I read I should not feel hunger on a ketogenic diet”… Well, let me tell you: Hunger is not necessarily a bad thing. Guys & Gals: have we become so “cognitive dissonant” and complacent, that we have forgotten that hunger is, in a way, a natural part of the process of any diet that the main focus is fat loss??? Any diet, be it keto or high carb, will eventually make you feel hungry. Yes, there are “ways” to trick your body and get “distracted” from the hunger signals, but being hungry is NORMAL, NATURAL and most of all, EXPECTED. There is nothing wrong with you if you experience hunger on keto…. and if you are eating as per the Ketogains macros (from our Ketogains MACRO calculator) – you are likely going to do well. “Eating more fat” just because you are “hungry” (and because someone told you you should be eating more fat) – UTTERLY defeats the purpose of a fat loss diet (and of course, #context dependent)…. because to lose body fat, you DO require an energy deficit. What can you do if you are hungry then? 1. Correct Macros. Check your macros are correctly calculated using OUR calculator. 2. Whole Food. Put an emphasis on WHOLE, nutrient dense foods, especially PROTEIN. Shakes are ok, for example, as a way to reach macros… but if you find yourself constantly hungry, you are better off eating chicken breast / beef, etc vs liquid calories. 3. Green Vegetables. Really: do you actually know you can eat almost a kilo of spinach a day, without disrupting keto? Go and look at the NET Carbs: 4. Soups. Try to increase food volume with liquids. My personal recipe for Continue reading >>