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What Is Ketoacidosis In Pregnancy

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Starvation Ketoacidosis In Pregnancy

Introduction: Starvation ketosis outside pregnancy is a rare phenomenon and is unlikely to cause a severe acidosis. Pregnancy is an insulin resistant state due to placental production of hormones including glucagon and human placental lactogen. Insulin resistance increases with advancing gestation and this confers a susceptibility to ketosis, particularly in the third trimester. Starvation ketoacidosis in pregnancy has been reported and is usually precipitated by a period of severe vomiting. Ketoacidosis has been associated with intrauterine death. Case report: A 22-year-old woman in her third pregnancy presented at 32 weeks gestation with a 24 h history of severe vomiting. She had been treated for an asthma exacerbation with prednisolone and erythromycin the day prior to presentation. She was unwell, hypertensive (145/70 mmHg) with a sinus tachycardia and Kussmaul breathing. Urinalysis showed ++++ ketones, + protein and pH 5. Fingerprick glucose was 4 mmol/l and ketones were 4.0 mmol/l. Arterial blood gas showed pH 7.27, PaCO2 1.1 kPa, base excess −23, bicarbonate 8.6 mmol/l and lactate 0.6 mmol/l. The anion gap was 20. Serum ethanol, salicylates and paracetamol levels were unde Continue reading >>

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Popular Questions

  1. Thomas

    I was also looking for a thread on expired test strips. I only make an assumption you have covered this but didn’t see a thread. Is my search flawed or have you really not explored expired test strips? (I assume I just did a bad search.) Or is it possible this one was too obvious to even have its own thread?

  2. Chris

    My guess is that they works just fine. But it is just an opinion. We haven’t had any expire, so unless someone has some expired ones laying around…

  3. Eric

    Expired Dexcom sensors work fine!
    I was also looking for a thread on expired test strips. I only make an assumption you have covered this but didn’t see a thread. Is my search flawed or have you really not explored expired test strips? (I assume I just did a bad search.) Or is it possible this one was too obvious to even have its own thread?
    I have never used an expired strip…

    Do you know why? I test about 20 times a day. How would a strip ever survive in my house long enough to expire!

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