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What Is Ketoacidosis Hyperglycemia

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Understanding And Treating Diabetic Ketoacidosis

Diabetic ketoacidosis (DKA) is a serious metabolic disorder that can occur in animals with diabetes mellitus (DM).1,2 Veterinary technicians play an integral role in managing and treating patients with this life-threatening condition. In addition to recognizing the clinical signs of this disorder and evaluating the patient's response to therapy, technicians should understand how this disorder occurs. DM is caused by a relative or absolute lack of insulin production by the pancreatic b-cells or by inactivity or loss of insulin receptors, which are usually found on membranes of skeletal muscle, fat, and liver cells.1,3 In dogs and cats, DM is classified as either insulin-dependent (the body is unable to produce sufficient insulin) or non-insulin-dependent (the body produces insulin, but the tissues in the body are resistant to the insulin).4 Most dogs and cats that develop DKA have an insulin deficiency. Insulin has many functions, including the enhancement of glucose uptake by the cells for energy.1 Without insulin, the cells cannot access glucose, thereby causing them to undergo starvation.2 The unused glucose remains in the circulation, resulting in hyperglycemia. To provide cells Continue reading >>

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Popular Questions

  1. Tirth Patel

    Blood Sugar Control and Stabilization

    Infectious Diseases

    Health


    Medicine and Healthcare



    How does an infection affect blood sugar? I understand the disease process, however what is the true science behind it?




    1 Answer







    Any type of Infection causes a stress response in the body by increasing the amount of certain hormones such as cortisol and adrenaline. These hormones work against the action of insulin so production of glucose increases, which results in high blood sugar levels.
    In a person who does not have diabetes, extra insulin is produced to counter these effects, but this is not possible for someone with diabetes.
    When your blood sugar is high, the white blood cells in your body are unable to “mop up” bacteria because they cannot move around at their normal speed and do not reach the infection site quickly enough to engulf and kill the bacteria.

    So in a diabetic person, hyperglycemia persists and it can lead to ketoacidosis during infection or any other type of stress.

    221 Views · 2 Upvotes · Answer requested by Amy Boumaig








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