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What Is Ketoacidosis Caused By

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How Can Diabetic Ketoacidosis Cause Cerebral Edema In Infants?

Diabetic Ketoacidosis (DKA) in and of itself does not cause cranial edema. What happens with DKA is the excess glucose in the blood changes the osmolarity of the blood, and causes fluid shift from intracelluar to extracellular. This causes the cells to shrink somewhat. Upon finding the patient in the DKA state, the teatment is insulin and IV fluids. Insulin and the hydration IV fluids reverse the DKA state, and also the osmolarity of the extracellular fluid, causing a fluid shift back into the cell. With the osmolarity reversed, the cells begin swelling—sometimes sometimes larger than before: this is what causes the edema in the cerebrum. This is particularly dangerous because the brain cells have nowhere to go, being encased within the skull. Even though infants have fontanelles and the skull has not fused solid, the extra fluid causes compression within the brain, which in turn can adversely affect the brain function. Continue reading >>

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  1. Javier Gómez

    Cervical cancer has a characteristic smell due to the presence of dibutyl phtalate, and other volatile organic compounds.
    In a diagnostic test trial a Beagle dog was trained to recognize cervical cancer odor. He was able to detect and discriminate cancer and non cancer odors with a sensitivity of 96,5% [95% CI 90,51 -100] a specificity of 99,55% [95% CI 98,8 - 100] and a positive predictive value of 96,36% [95% IC 90,51 - 100].
    There are other reports about dogs ability to sniff out breast cancer, lung cancer, colon cancer and bladder cancer (this last one with a sensibility of 41%), narcolepsy, migraines and hypoglycemia .
    Sources:
    Guerrero-Flores et al. A non-invasive tool for detecting cervical cancer odor by trained scent dogs. BMC Cancer (2017) 17:79
    Willis Carolyn et al. Olfatory detection of human bladder cancer by dogs: proof of principle study. BMJ (2004);329:712

    6 Medical Conditions That Dogs Can Sniff Out

  2. Xu Beixi

    Fetor hepaticus , symptomatic of portal hypertension.
    Uremic fetor , symptomatic of chronic kidney disease.
    Bad breath, could be caused by not brushing, as well as “disorders in the nose , sinuses , throat , lungs , esophagus , or stomach ”. Diabetic ketoacidosis can give one a fruity/acetone smelling breath, too.

    Body odor, commonly harmless, could be caused by certain types of food, microbes on the skin, gland secretions, getting sprayed by a skunk, etc. Metabolic disorders can cause one to smell odd; people who can’t process an amino acid called phenylalanine smell musty, and those with trimethylaminuria smell fishy.
    And from a rather humourously written paper:
    Infectious diseases were known by their characteristics odors--scrofula as smelling like stale beer; typhoid, like freshly baked brown bread; rubella, like plucked feathers; and diphtheria, as "sweetish." Anosmics might be banned from medical school.

    What does Candida smell like--a "heavy sweetness"? Darier's disease in poor control--"organic"? Pseudomonal infections--"foul and biting"? And are not our patients with noninfected eczematous dermatitis distinct for lacking any peculiar odor, do they not actually smell "dry"?

    Scratch and sniff. The dynamic duo.

  3. Matt Morgan

    There are numerous bad stinks I have come across, but the one that made me almost vomit was a patient with gastrocolic fistula. In this disease, the large intestine somehow gets connected to the stomach, so the fecal material refluxes into stomach and the patient has poo stink breath.

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Alcoholic Ketoacidosis

Alcoholic ketoacidosis is a metabolic complication of alcohol use and starvation characterized by hyperketonemia and anion gap metabolic acidosis without significant hyperglycemia. Alcoholic ketoacidosis causes nausea, vomiting, and abdominal pain. Diagnosis is by history and findings of ketoacidosis without hyperglycemia. Treatment is IV saline solution and dextrose infusion. Alcoholic ketoacidosis is attributed to the combined effects of alcohol and starvation on glucose metabolism. Alcohol diminishes hepatic gluconeogenesis and leads to decreased insulin secretion, increased lipolysis, impaired fatty acid oxidation, and subsequent ketogenesis, causing an elevated anion gap metabolic acidosis. Counter-regulatory hormones are increased and may further inhibit insulin secretion. Plasma glucose levels are usually low or normal, but mild hyperglycemia sometimes occurs. Diagnosis requires a high index of suspicion; similar symptoms in an alcoholic patient may result from acute pancreatitis, methanol or ethylene glycol poisoning, or diabetic ketoacidosis (DKA). In patients suspected of having alcoholic ketoacidosis, serum electrolytes (including magnesium), BUN and creatinine, glucose, Continue reading >>

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  1. Hans Luijendijk

    Ketosis is a normal metabolic process in your body. If you don't have sufficient glucose in your body, it will turn to burning fat. A process we call ketosis.
    It does not cause kidney damage in healthy people with normal balanced food intake.

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Ketoacidosis Caused By Anorexia Nervosa

Please log in to add your comment. Transcript of Ketoacidosis caused by Anorexia Nervosa Ketoacidosis caused by Anorexia Nervosa Resources Symptoms Weakness, Tiredness Nasuea Shortness of Breath Vomiting High Blood Sugar, Rapid Pulse Low Blood Pressure Extreme Thirst Frequent Urination Leg Cramps Treatment Take in lots of Fluids Take in lots of Electrolytes Insulin treatment to lower high blood sugar levels How It Relates To Other Body Systems Ketoacidosis keeps blood sugar high, leading to nerve, blood vessel and kidney damage, as well as worsening pancreatic damage which in turn makes the condition more severe. What Further Tests are Needed Electrolyte test: Potassium, sodium, blood urea, serum, Ketone levels and kidney function markers along with an arterial blood gas sample are the electrolyte tests for ketoacidosis. • Other tests may be used to check underlying conditions , based on the history and physical examination findings. These may include chest x-ray, urine analysis and possible scan of brain Urinalysis and Connection to results Ketones are detected in the blood using urinalysis Ketones build up when the body needs to break down fats and fatty acids to use as fuel. T Continue reading >>

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Popular Questions

  1. Javier Gómez

    Cervical cancer has a characteristic smell due to the presence of dibutyl phtalate, and other volatile organic compounds.
    In a diagnostic test trial a Beagle dog was trained to recognize cervical cancer odor. He was able to detect and discriminate cancer and non cancer odors with a sensitivity of 96,5% [95% CI 90,51 -100] a specificity of 99,55% [95% CI 98,8 - 100] and a positive predictive value of 96,36% [95% IC 90,51 - 100].
    There are other reports about dogs ability to sniff out breast cancer, lung cancer, colon cancer and bladder cancer (this last one with a sensibility of 41%), narcolepsy, migraines and hypoglycemia .
    Sources:
    Guerrero-Flores et al. A non-invasive tool for detecting cervical cancer odor by trained scent dogs. BMC Cancer (2017) 17:79
    Willis Carolyn et al. Olfatory detection of human bladder cancer by dogs: proof of principle study. BMJ (2004);329:712

    6 Medical Conditions That Dogs Can Sniff Out

  2. Xu Beixi

    Fetor hepaticus , symptomatic of portal hypertension.
    Uremic fetor , symptomatic of chronic kidney disease.
    Bad breath, could be caused by not brushing, as well as “disorders in the nose , sinuses , throat , lungs , esophagus , or stomach ”. Diabetic ketoacidosis can give one a fruity/acetone smelling breath, too.

    Body odor, commonly harmless, could be caused by certain types of food, microbes on the skin, gland secretions, getting sprayed by a skunk, etc. Metabolic disorders can cause one to smell odd; people who can’t process an amino acid called phenylalanine smell musty, and those with trimethylaminuria smell fishy.
    And from a rather humourously written paper:
    Infectious diseases were known by their characteristics odors--scrofula as smelling like stale beer; typhoid, like freshly baked brown bread; rubella, like plucked feathers; and diphtheria, as "sweetish." Anosmics might be banned from medical school.

    What does Candida smell like--a "heavy sweetness"? Darier's disease in poor control--"organic"? Pseudomonal infections--"foul and biting"? And are not our patients with noninfected eczematous dermatitis distinct for lacking any peculiar odor, do they not actually smell "dry"?

    Scratch and sniff. The dynamic duo.

  3. Matt Morgan

    There are numerous bad stinks I have come across, but the one that made me almost vomit was a patient with gastrocolic fistula. In this disease, the large intestine somehow gets connected to the stomach, so the fecal material refluxes into stomach and the patient has poo stink breath.

  4. -> Continue reading
read more close

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