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What Is Fully Compensated Respiratory Acidosis?

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4.5 Respiratory Acidosis - Compensation

Acid-Base Physiology 4.5.1 The compensatory response is a rise in the bicarbonate level This rise has an immediate component (due to a resetting of the physicochemical equilibrium point) which raises the bicarbonate slightly. Next is a slower component where a further rise in plasma bicarbonate due to enhanced renal retention of bicarbonate. The additional effect on plasma bicarbonate of the renal retention is what converts an "acute" respiratory acidsosis into a "chronic" respiratory acidosis. As can be seen by inspection of the Henderson-Hasselbalch equation (below), an increased [HCO3-] will counteract the effect (on the pH) of an increased pCO2 because it returns the value of the [HCO3]/0.03 pCO2 ratio towards normal. pH = pKa + log([HCO3]/0.03 pCO2) 4.5.2 Buffering in Acute Respiratory Acidosis The compensatory response to an acute respiratory acidosis is limited to buffering. By the law of mass action, the increased arterial pCO2 causes a shift to the right in the following reaction: CO2 + H2O <-> H2CO3 <-> H+ + HCO3- In the blood, this reaction occurs rapidly inside red blood cells because of the presence of carbonic anhydrase. The hydrogen ion produced is buffered by intrac Continue reading >>

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Popular Questions

  1. Punkin

    I think I need to start using one, especially since I have some dietary challenges
    Does anyone have one that is recommended. Also where can I get one and how much do they cost approximately.
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  2. Mobear

    I'm not an expert on this since I just purchased mine this last week . I think the only 2 available are from Precision and NovaMax. Precision tends to be a little more accurate but the strips are REALLY expensive. NovaMax doesn't seem to be quite as accurate (at least with glucose readings) but the strips are a little more reasonable. I usually look up this kind of thing on amazon. Some people have reported good prices from american diabetes wholesale so you might want to look there also.
    Just remember that the meter has to check blood ketones - not just glucose. Any strips you are looking at must check blood ketones - not the urine ketones (those strips are very inexpensive).
    Others will chime in with more info I'm sure

  3. UnstrungHarp

    I'm no expert either, but I got my Precision reader for free. We can't post links here, but I think if you Google "free Precision Xtra meter" the top search result should be the right one. It's totally legit - straight from the manufacturer. Also, the fact that the form asked for insurance info freaked me out, but apparently that's nothing. They didn't even have my insurance company in their selection list, so I chose a random one. I got my meter delivered via FedEx within a week!
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    The only problem I've had with that pharmacy was that my second order of strips was very delayed because for some reason they had to talk to me on the phone to verbally confirm my order. And they didn't let me know this until several days after I placed my order. On the phone I asked them, why didn't I have to do this with my first order? They said that it was standard practice on all orders, and it was unusual that I didn't have to the first time. Well, when I got ready to place my third order, I crossed my fingers and tried it online again without calling...turns out no phone call was necessary that time either.
    Whichever meter you choose - good luck!!!

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