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What Is Distal Renal Tubular Acidosis?

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* at 6:58 i said hpo3-. please correct it to hpo4 3-. * at 6:23 i said calcium oxalate stones, it should be calcium phosphate stones. please correct that.

Distal Renal Tubular Acidosis

Also known as: Renal tubular acidosis - distal, Renal tubular acidosis type I, Type I RTA, RTA - distal or Classical RTA Distal renal tubular acidosis is a disease that occurs when the kidneys do not properly remove acids from the blood into the urine. As a result, too much acid remains in the blood (called acidosis ). When the body performs its normal functions, it produces acid. If this acid is not removed or neutralized, the blood becomes too acidic. This can lead to electrolyte imbalances in the blood. It can also cause problems with normal function of some cells. The kidneys help control the body's acid level by removing acid from the blood and excreting it into the urine. Distal renal tubular acidosis (Type I RTA) is caused by a defect in the kidney tubes that causes acid to build up in the blood. Type I RTA is caused by a variety of conditions, including: Amyloidosis , a buildup of abnormal protein, called amyloid, in the tissues and organs Fabry disease, an abnormal buildup in the body of a certain type of fatty substance Sickle cell disease , red blood cells that are normally shaped like a disk take on a sickle or crescent shape Sjgren syndrome , an autoimmune disorder in Continue reading >>

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  1. thebigloss

    Welcome to the Active Low-Carber Forums
    Support for Atkins diet, Protein Power, Neanderthin (Paleo Diet), CAD/CALP, Dr. Bernstein Diabetes Solution and any other healthy low-carb diet or plan, all are welcome in our lowcarb community. Forget starvation and fad diets -- join the healthy eating crowd! You may register by clicking here, it's free!

  2. Nancy LC

    I think that's sort of like asking how blue the sky is. It depends. :p

  3. thebigloss

    :P true but like on the average? or ~

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kaplanmedical.com/S1HY - Preview and share samples from Kaplan's fast-paced, comprehensive USMLE Step 1 review program - free. Our video lectures contain only the high-yield information you need to master for a high score on test day. Click the link above to learn more about Kaplan's Step 1 High Yield.

Distal Renal Tubular Acidosis Sequencing Panel - Preventiongenetics

Distal Renal Tubular Acidosis Sequencing Panel We are happy to accommodate requests for single genes or a subset of these genes. The price will remain the list price. If desired, free reflex testing to remaining genes on panel is available. Alternatively, a single gene or subset of genes can also be ordered on our PGxome Custom Panel. For ordering targeted known variants, please proceed to our Targeted Variants landing page. The great majority oftests are completed within 28 days. Detection rate of pathogenic variants in SLC4A1 and CA2 in a large cohort of patients with distal renal tubular acidosis (dRTA) is unknown in the literature because only a limited number of cases have been reported. In the original study that identified ATP6V1B1 pathogenic variants in autosomal recessive dRTA, Karet et al. studied 31 unrelated kindred (27 had family history of consanguineous marriage) and found ATP6V1B1 pathogenic variants in 19 (61%) cases (Karet et al. 1999). In another study of 26 patients with autosomal recessive dRTA, of which 23 were consanguineous, ATP6V1B1 pathogenic variants were found in 10 (38%) cases (Stover et al. 2002). In the original study that identified ATP6V0A4 pathoge Continue reading >>

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  1. loislane

    Measuring ketones?

    I have been eating low carb (prob less than 40-50/day ... TC - not net carbs) for about 2 months now. Haven't made a conscious decision to go keto but am curious how close/far I am given this level of eating.
    Seems like the strips are the cheapest way to go - are there particular brands that are better than others, and do results differ significantly the way they do with meters?
    How frequently do you measures (daily, weekly, etc.)

    I've read you need to maintain between 1 and 3 to be in keto - is there any benefit to having some ketones but not at that level? How long does it take you get back once you slip out with a meal or day?
    TIA!

  2. SuperMario

    Originally Posted by loislane
    I have been eating low carb (prob less than 40-50/day ... TC - not net carbs) for about 2 months now. Haven't made a conscious decision to go keto but am curious how close/far I am given this level of eating. That is pretty good. Congrats on being so consistent and on the track!

    Originally Posted by loislane
    Seems like the strips are the cheapest way to go - are there particular brands that are better than others, and do results differ significantly the way they do with meters? Yes, sticks are dirt cheap but ridden with problems. I don't think that there is much significant difference between brands including generic one. Here are few issues:
    - It may get a little tricky to compare colors to get the accurate reading.
    - Even if you have luck with matching colors, the ranges shown are pretty "approximate".
    - If you are in ketosis for a while (seems like you maybe that case), urine keto strips stop showing the full extent of your ketosis, i.e. readings are low despite the fact that your ketones are up. The issue is that urine strips test only for acetoacetate ketones, and not for more important beta hydroxybutyrate.
    - So, keto urine sticks may not be very useful for what you are trying to do at the moment, but certainly better something than nothing.
    I would recommend using Blood Ketone Meter. For example, Xtra Precision which costs around $25 plus $3-$4/ketone strip. You can find good prices on Amazon.

    Originally Posted by loislane
    How frequently do you measures (daily, weekly, etc.) It is enough in the morning (to save $ esp. on blood ketone strips). If you want to experiment and have more fun, you can do it after longer period of not eating food during the day.

    Originally Posted by loislane
    I've read you need to maintain between 1 and 3 to be in keto - is there any benefit to having some ketones but not at that level? How long does it take you get back once you slip out with a meal or day?
    Ideal range is 1.5-3.0 mmol. Light nutritional ketosis is 0.5-1.5 mmol. See below.
    Yes, there is some benefit to being in "light" ketosis as opposed into the "full".
    If you slip, on average, it may take 2-4 days to get back to the track.

  3. CalgaryDiabetic

    The best strips are freestyle blood strips that measure Betahydroxybutyrate. Urine strips measure god only knows what.

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U-World Concept Series: Renal Tubular Acidosis Hi medical students!!! I am so glad that you guys are enjoying this series and it has been helping you! Please, do share the videos with classmates and friends! I tried my best to explain renal tubular acidosis so to get a better understanding of WHY renal tubular acidosis occurs and HOW and what is the presentation, what is it associated with and the treatment. I also really emphasize the difference between the three! This topic is seen in both step 1 and step 2 USMLE exams! It will also be seen in your in house exams in your medical school! Thank you for you support!! Firecracker - http://mbsy.co/hSZGp Kaplan - https://goo.gl/UJATPJ OB/GYN Clinical Experience - https://www.youtube.com/watch? v=3pC2MVDlLBw OB/GYN High Yield Topics - https://www.youtube.com/watch?v=JDaAV... U-World Concept Series: STRESS, URGE, OVERFLOW INCONTINENCE: https://youtu.be/3v0xA3Vlh_o Pediatrics core rotation: https://youtu.be/sBQP0F_G63Q My USMLE Step 1 Resources: https://youtu.be/lr_PhQGJVAc Psychiatry core rotation: https://youtu.be/xn2d8o4080Y U-World Concept Series: Adrenal Insufficiency: youhttps://tu.be/asBAC2ShWc0 U-World Concept Series: Heparin indu

Distal Renal Tubular Acidosis

Renal tubular acidosis - distal; Renal tubular acidosis type I; Type I RTA; RTA - distal; Classical RTA Distal renal tubular acidosis is a disease that occurs when the kidneys do not properly remove acids from the blood into the urine. As a result, too much acid remains in the blood (called acidosis ). The kidneys are responsible for removing wastes from the body, regulating electrolyte balance and blood pressure, and the stimulation of red blood cell production. This is the typical appearance of the blood vessels (vasculature) and urine flow pattern in the kidney. The blood vessels are shown in red and the urine flow pattern in yellow. When the body performs its normal functions, it produces acid. If this acid is not removed or neutralized, the blood becomes too acidic. This can lead to electrolyte imbalances in the blood. It can also cause problems with normal function of some cells. The kidneys help control the body's acid level by removing acid from the blood and excreting it into the urine. Distal renal tubular acidosis (Type I RTA) is caused by a defect in the kidney tubes that causes acid to build up in the blood. Type I RTA is caused by a variety of conditions, including: Continue reading >>

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  1. Roark

    Hey Guys,
    I realize I really have no clue what exactly is going on with ketosis or some of the diet in general, so any help in shedding light on it would be greatly appreciated! Please feel free to answer one or any of the following questions:
    1) I always thought ketosis occurred when one severely restricts carb intake, but I also know ketosis is the result of intermittent fasting. Does it happen under both situations independently, or must one both restrict carbs plus incorporate intermittent fasting to enter Ketosis?
    2) How quickly should one be able to enter ketosis? When not in ketosis, does this mean the body is storing fat and burning glucose?
    3) If while in ketosis the body is burning fat for fuel, wouldn't a high fat diet make available so much dietary fat that the body never needs to burn already stored fat for energy?
    4) What color should be targeted when using Ketostix, as I tend to get between small and medium after a week of less than 30 carbs daily. When is the best time of day to test with ketostix?
    5) When eating too many carbs to enter ketosis, does this mean that the body will naturally burn glucose before burning any fat? Is dietary fat stored when not in ketosis?
    6) If one eats regularly and stays bulletproof, but does not use intermittent fasting, does this mean the body does not enter ketosis and therefore the body never starts burning fat for energy, but instead stores eat? If not - what happens to all the dietary fat in the BP diet when not in ketosis?
    7) Is it safe for a friend who is not on the BP diet to consume high fat BP foods like BP Ice Cream - or will that lead to more fat storage than if they were to just eat regular, lower fat, higher sugar ice cream?
    I've been following and tweaking the diet for myself, but realize I really don't know what happens and why, so thanks in advance for all your help!

  2. Valentinoff

    1) I believe being in ketosis and IF are independent events. You can be in ketosis without IF'ing (by being low carb) and you can IF but not be in Ketosis (high carb when not fasting)
    7) I've read that you ought to give your friend some kind of supplement to aid with the fat digestion with 'Get Some' ice cream. A long timer on the forum would have to expand on this with the exact supplement/ingredient...
    I'm not so sure about the rest as I'm also at the beginning of my Bulletproof journey =D

  3. Roark

    1) I believe being in ketosis and IF are independent events. You can be in ketosis without IF'ing (by being low carb) and you can IF but not be in Ketosis (high carb when not fasting)
    7) I've read that you ought to give your friend some kind of supplement to aid with the fat digestion with 'Get Some' ice cream. A long timer on the forum would have to expand on this with the exact supplement/ingredient...

    I'm not so sure about the rest as I'm also at the beginning of my Bulletproof journey =D
    Oh yea, now that you mention it, I do recall hearing Dave talk somewhere about normal diet people needing to somehow supplement the high fat consumption.
    I'm not so sure about #1, as I remember hearing Dave talk about why the consumption of BP Coffee doesn't break the ketosis because of the high MCT, but possibly other foods, even eggs and beef might not work in the same way, since the liver would still be required to start working again? I could be way off, but if someone can remain in ketosis even while eating BP food very often, what would the point be of fasting? Furthermore, I've noticed in myself that even on a strict BP diet, without intermittent fasting, I tend to gain weight slowly, which makes no sense if I'm in fat burning mode...unless it has to do with my question #3 above, and you eat more fat than the body can burn?

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