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What Is Anion Gap Metabolic Acidosis?

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Metabolic Acidosis And The Anion Gap

Decrease in pH due to decrease in serum HCO3- Related to either loss of HCO3- or gain of H+ caused by: -Exogenous acid=e.g. ethylene glycol overdose -Kidneys=e.g. proximal renal tubular acidosis (Type 2 RTA) 3. Inability to excrete normal daily acid production by kidneys-e.g. advanced kidney disease, distal renal tubular acidosis (Type 1 RTA) Laboratory Findings in Metabolic Acidosis Decreased pCO2 (to compensate for low HCO3-) Clinically divide metabolic acidoses based on whether patient has elevated anion gap or normal anion gap Anion Gap=difference between measured cations and anions What are the common circulating cations and anions? Cations: Sodium, Potassium, Calcium, Magnesium, Proteins Anions: Chloride, Bicarbonate, Sulfates, Phosphates, Albumin, Other proteins Not practical to measure all of these, so the ones easiest to measure/in greatest abundance are measured=Sodium, Chloride, and Bicarbonate Normal Anion Gap Metabolic Acidosis (Hypercholermic metabolic acidosis) Normal anion gap metabolic acidosis characterized by decrease in bicarbonate and increase in chloride =HCl+NaHCO3-> NaCl +H2CO3-> CO2+ H2O+ NaCl H+ +Cl- +HCO3- -> Cl- + H2CO3-> H2O+CO2 +Cl- Net result=loss of Continue reading >>

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  1. yogipete

    I've wanted a ketonix for a while but am not going to fork over hundreds of dollars. So I followed some advice and got myself a cheap breathalyzer on ebay. Apparently they don't distinguish between alcohol and acetone.
    IT WORKS!
    Now I can measure easily whether or not I am in ketosis anytime I suspect I may have dropped out. The ketostix stopped working for me a long time ago as my body is very well adapted and I don't excrete a lot of measurable ketones.The breathalyzer is not much good for finding your millimoler value of ketones, but then again, by all accounts neither is a ketonix itself. The breathalyzer cost me $12 and you can get them cheaper. In fact, it's only the cheaper ones that work. You can get these breathalyzers as cheap as a few dollars.
    Here's the one I used below

    That reading above is while fully sober... * I swear * Only trouble is it beeps like crazy when it detects 0.05% or over (the legal alcohol driving limit in australia). I'm sure other models wouldn't beep.


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    Ketone meter
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    Breath Meter
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    Not seeing many results after ~1-2 month
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    Keto Strips - No Ketones!
    25
    Testing ketones
    21

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    Engineering Myself: Using a Cheap Breathalizer to Measure Ketosis engineeringmyself.com

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    Ketone meter ketogenicforums.com

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    Ketones from following a low-carb diet could trigger the breathalyzer proteinpower.com

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    Breath Alcohol Tester Pro ALC Smart Digital LCD Breathalyzer Analyzer AT6000 MG | eBa... ebay.com.au


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    https://jenslabs.com/2013/06/06/ketosense-an-arduino-based-ketosis-detector/





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  2. BillJay

    Thanks @yogipete ! This is both interesting and worrisome at the same time!

    I may get a cheap one myself, but in the meantime I'd love to see if others can replicate your results.

  3. yogipete

    My pleasure.

    I might also add that the reading is consistent regardless of my method of blowing etc... which is a problem that haunts the ketonix. I've done a few baseline tests on my partnerr who always blows 0 (she's currently non-keto) while I generally blow between .04 and .05 (but in any one moment of the day the reading is always identical regardless of my personal clumsiness in using the meter). I'm looking forward to testing some more non-keto friends.

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Review Of The Diagnostic Evaluation Of Normal Anion Gap Metabolic Acidosis

Acid-Base, Electrolyte and Fluid Alterations: Review Review of the Diagnostic Evaluation of Normal Anion Gap Metabolic Acidosis I have read the Karger Terms and Conditions and agree. I have read the Karger Terms and Conditions and agree. Buy a Karger Article Bundle (KAB) and profit from a discount! If you would like to redeem your KAB credit, please log in . Save over 20% compared to the individual article price. Buy Cloud Access for unlimited viewing via different devices Access to all articles of the subscribed year(s) guaranteed for 5 years Unlimited re-access via Subscriber Login or MyKarger Unrestricted printing, no saving restrictions for personal use * The final prices may differ from the prices shown due to specifics of VAT rules. For additional information: Background: Normal anion gap metabolic acidosis is a common but often misdiagnosed clinical condition associated with diarrhea and renal tubular acidosis (RTA). Early identification of RTA remains challenging for inexperienced physicians, and diagnosis and treatment are often delayed. Summary: The presence of RTA should be considered in any patient with a high chloride level when the CL-/Na+ ratio is above 0.79, if the Continue reading >>

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  1. nboylie

    I have searched rexall and shoppers drug mart and I can't seem to find them?

  2. quality_time

    I get mine at shoppers. I ask for them from the pharmacist as they keep them behind the counter. I've also gotten them from the pharmacy at the grocery store - same deal behind the counter. If they don't have them behind the counter it's on order. Typically with the diabetic stuff.

  3. rolodex9

    yep, Shoppers has them behind the pharmacists counter. In regards to how expensive they are, I combat that by cutting mine in half. They're still readable and instead of 50 you get 100 strips

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Metabolic Acidosis

Diabetic Ketoacidosis (DKA), Alcohol ic ketoacidosis or starvation ketosis Paraldehyde, Phenformin (neither used in U.S. now) Propofol Infusion Syndrome has been proposed as a replacement in mnemonic Salicylate s (do not miss Chronic Salicylate Poisoning ) IV. Causes: Metabolic Acidosis and Normal Anion Gap (Hyperchloremia) Renal Tubular Acidosis (proximal or distal) V. Causes: Metabolic Acidosis and Elevated Osmolal Gap PaCO2 drops 1.2 mmHg per 1 meq/L bicarbonate fall Calculated PaCO2 = 1.5 x HCO3 + 8 (+/- 2) Useful in High Anion Gap Metabolic Acidosis Measured PaCO2 discrepancy: respiratory disorder Investigate normal Anion Gap Metabolic Acidosis Elevated in normal Anion Gap Metabolic Acidosis VII. Labs: Consider in Metabolic Acidosis with Increased Anion Gap Basic chemistry panel as above ( Serum Glucose , Blood Urea Nitrogen ) Rutecki (Dec 1997) Consultant, p. 3067-74 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Metabolic Acidosis." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images Related Studies (from Trip Database) Open in New W Continue reading >>

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  1. Margot LaNoue

    A few methods:
    - pee on a stick. There's a generic brand (I use Walgreen's) and the official brand. In general, they're called "ketone test strips" and they will change colors depending on the amount of ketone bodies in your urine. There is no "perfect level" of ketone bodies; you are either in ketosis or you are not. You will find these test strips in the same isle as the diabetic test stuff.
    - smell your breath. It will smell *awful* because a side product of ketosis is acetone in the urine and breath. While urine might always smell bad to you, your breath will smell truly, noticeably foul.
    - no bloating. Ketones do not bind with water the way glucose/glycogen does. You will not retain water when in ketosis. Nice!

  2. Cherie Nixon

    Warning: this might gross you out, but there's a simple answer to this question.
    OK, you want to know how you can tell? If you're in ketosis, you will often find oily residue floating in the toilet (assuming adequate lighting to see it). That's because while in ketosis, you excrete excess fat calories.

  3. Gary Wayne Nettoc

    The taste that people have mentioned is from the acetone in your breath, produced when you are in ketosis. There's a cool gadget that can measure that and let you know if you are in ketosis. KETONIX by Moose AB, Org.nr 556443-3794 It doesn't require strips or any replacement parts so in the long run it is the cheapest alternative.

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