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What Is A Normal Ketone Level?

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Are Both Type 1 And Type 2 Diabetes Patients At The Risk Of Death?

Are both type 1 and type 2 diabetes patients at the risk of death? Yes, absolutely. Every single person on the planet with Type 1 and Type 2 diabetes will die. But don’t worry, so will everyone else - it is all just a matter of time. The real question should be are they at risk of a premature death due to their conditions, and unfortunately the answer to that is also yes for various reasons. The first reason is the impact of long-term high blood glucose levels, including damage to large and small blood vessels, which can lead to heart attack and stroke, and problems with the kidneys, eyes, feet and nerves. Another risk often overlooked is overdosing on insulin. Insulin is a highly dangerous hormone, taking too much will cause a person to slip into a hypoglycemic coma which can lead to death. Alternatively, it is possible to die from not getting enough (or any insulin), due to Diabetic ketoacidosis Continue reading >>

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  1. Michael L. Jirka

    Ketones are produced when the body has to use fats for energy. ketones and Beta Hydroxy Butyric acid are byproducts. You, as a type 1 diabetic take insulin more than once a day because your pancreas is weak from a virus or you have an autoimmune antibody destroying your natural insulin. Either way, you are not an UNDIAGNOSED diabetic who has never had an insulin shot, and even though your sugar was very high, you took insulin and the body will always utilize glucose before it uses fats and proteins for energy. AND THAT IS WHY I THINK IT IS POSSIBLE IN YOUR CASE.

  2. Aerie Robinson

    I am high frequently - getting much better though, go me - I would also dump ketones, when I felt like checking them, but would also often not dump them as often as i would think for being as high as I was. I'd be 400+ and have none or very low ketones.

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How Is Methylglyoxal Produced In Ketosis?

As dry as this question sounds, this is a fascinating and relevant topic. At its heart lies the issue of how diabetes (and possibly low-carb diets) can predispose you to atherosclerosis. And heart attacks (pun totally unintended). But to get there, we have to review some chemistry. That's where methylglyoxal and ketosis come in. Bear with me. Above is a useful summary diagram. Keep reading for more details on the actual processes. To clarify: ketosis is not a chemical reaction per se. It's the state where the body derives most of its energy supply by metabolizing ketone bodies. Normally, we derive most of our energy through glycolysis and the concentration of ketone bodies is less than 0.5mM [1]. Levels above this are associated with ketosis. For example, diabetics with severe ketosis might have concentrations of 10mM [1]. The liver produces ketones from fats to meet the body's energy needs when there is a lack of glucose and glycogen. So you can see why ketosis might arise not just in diabetics, but also in people on low-carb diets like the Atkins [2]. Fat (triacylglycerol) is broken down into three fatty acid chains and one glycerol molecule (this process is called lipolysis). Th Continue reading >>

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  1. Michael L. Jirka

    Ketones are produced when the body has to use fats for energy. ketones and Beta Hydroxy Butyric acid are byproducts. You, as a type 1 diabetic take insulin more than once a day because your pancreas is weak from a virus or you have an autoimmune antibody destroying your natural insulin. Either way, you are not an UNDIAGNOSED diabetic who has never had an insulin shot, and even though your sugar was very high, you took insulin and the body will always utilize glucose before it uses fats and proteins for energy. AND THAT IS WHY I THINK IT IS POSSIBLE IN YOUR CASE.

  2. Aerie Robinson

    I am high frequently - getting much better though, go me - I would also dump ketones, when I felt like checking them, but would also often not dump them as often as i would think for being as high as I was. I'd be 400+ and have none or very low ketones.

  3. -> Continue reading
read more
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Moof's Medical Biochemistry Video Course: http://moof-university.thinkific.com/... In this video, I describe how Ketone Bodies are oxidized for energy. The liver makes ketone bodies that travel through the blood to extrahepatic tissues, where they are oxidized in the mitochondrial matrix to give energy. The pathway begins with D--Hydroxybutyrate, as it is oxidized to Acetoacetate by the same D--Hydroxybutyrate Dehydrogenase reaction (except in reverse). The Acetoacetate is then activated to Acetoacetyl-CoA by -Ketoacyl-CoA Transferase (also known as Thiophorase); this second step takes a Coenzyme A from Succinyl-CoA (an intermediate of the Krebs Cycle). The Acetoacetyl-CoA is then cleaved into two Acetyl-CoA molecules that can go through the Krebs Cycle to be oxidized, resulting in energy that cell can use. Ultimately, the liver is basically sending Acetyl-CoA that it isnt metabolizing to other tissues (by way of Ketone Bodies in the blood) so that those other tissues can utilize the Acetyl-CoA. However, sometimes, the extrahepatic tissues do not oxidize the ketone bodies rapidly enough to keep up with the pace at which they are arriving from the blood. This is a problem described

What Are Ketone Bodies And How Are They Related To Diabetes?

What are ketones? The human body normally runs on glucose that’s produced when the body breaks down carbohydrates. But when your body doesn’t have enough glucose or insulin to use the glucose, your body starts breaking down fats for energy. Ketones are byproducts of this breakdown. Those with type 1 diabetes are especially at risk for making ketones. Ketones can make your blood acidic. Acidic blood can cause a serious condition known as diabetic ketoacidosis (DKA). Because the presence of ketones is often one of the signs that a person needs medical help, those with diabetes are often encouraged to check ketones in urine or blood regularly. Ketone levels can range from negative or none at all to very high levels. While individual testing may vary, some general results for ketone levels can be: negative: less than 0.6 millimoles per liter (mmol/L) low to moderate: between 0.6 to 1.5 mmol/L high: 1.6 to 3.0 mmol/L very high: greater than 3.0 mmol/L Call your doctor if your ketones are low to moderate, and seek emergency medical attention if your ketone levels are high to very high. What are the symptoms of ketone buildup? If you have diabetes, you need to be especially aware of t Continue reading >>

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Popular Questions

  1. Michael L. Jirka

    Ketones are produced when the body has to use fats for energy. ketones and Beta Hydroxy Butyric acid are byproducts. You, as a type 1 diabetic take insulin more than once a day because your pancreas is weak from a virus or you have an autoimmune antibody destroying your natural insulin. Either way, you are not an UNDIAGNOSED diabetic who has never had an insulin shot, and even though your sugar was very high, you took insulin and the body will always utilize glucose before it uses fats and proteins for energy. AND THAT IS WHY I THINK IT IS POSSIBLE IN YOUR CASE.

  2. Aerie Robinson

    I am high frequently - getting much better though, go me - I would also dump ketones, when I felt like checking them, but would also often not dump them as often as i would think for being as high as I was. I'd be 400+ and have none or very low ketones.

  3. -> Continue reading
read more

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