What Does Ketoacidosis Mean?

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What is BASAL RATE? What does BASAL RATE mean? BASAL RATE meaning - BASAL RATE definition - BASAL RATE explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... In biology, basal rate is the rate of continuous supply of some chemical or process. In the case of diabetes mellitus, it is a low rate of continuous insulin supply needed for such purposes as controlling cellular glucose and amino acid uptake. Together with a bolus of insulin, the basal insulin completes the total insulin needs of an insulin-dependent person. An insulin pump and wristop controller is one way to arrange for a closely controlled basal insulin rate. The slow-release insulins (e.g., Lantus and Levemir) can provide a similar effect. In healthy individuals, basal rate is monitored by the pancreas, which provides a regular amount of insulin at all times. The body requires this flow of insulin to enable the body to utilize glucose in the blood stream, so the energy in glucose can be used to carry out bodily functions. Basal rate requirements can differ for individuals depending

Princeton's Wordnet(0.00 / 0 Votes)rate This Definition:

acidosis with an accumulation of ketone bodies; occurs primarily in diabetes mellitus A severe form of ketosis, most commonly seen in diabetics, in which so much ketone is produced that acidosis occurs. Origin: From ketones + acidosis Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids. The two common ketones produced in humans are acetoacetic acid and β-hydroxybutyrate. Ketoacidosis is a pathological metabolic state marked by extreme and uncontrolled ketosis. In ketoacidosis, the body fails to adequately regulate ketone production causing such a severe accumulation of keto acids that the pH of the blood is substantially decreased. In extreme cases ketoacidosis can be fatal. Ketoacidosis is most common in untreated type 1 diabetes mellitus, when the liver breaks down fat and proteins in response to a perceived need for respiratory substrate. Prolonged alcoholism may lead to alcoholic ketoacidosis. Ketoacidosis can be smelled on a person's breath. This is due to acetone, a direct byproduct of the spontaneous decomposition of acetoacetic acid. It is often described as smelli Continue reading >>

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  1. Rhapsody

    Why does citric acid knock some people out of ketosis???
    Does it have anything to do with the KREB cycle?

  2. Sheesh

    Citric acid plays a key part in the Kreb Cycle (aka the "Citric Acid Cycle"), simply because it the 6-carbon molecule that pretty much starts the cycle is indeed Citric Acid (acetyl-coa combines with oxaloacetate to form the citric acid, and this is the first step of the cycle).
    But, no, it's not going to knock you out of ketosis.

  3. spike1205

    Sheesh--from what ive read (or atleast rememebr) citric acid does/can knock you out of ketosis. I dont know the research on it and tend to believe it is more likely other ingredients in foods containing citric acid (ie aspartame in diet sodas) but i have read repeatedly that citric acid does and can --Rhaps--i sont have a clue how

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Diagnosis And Treatment Of Diabetic Ketoacidosis And The Hyperglycemic Hyperosmolar State

Go to: Pathogenesis In both DKA and HHS, the underlying metabolic abnormality results from the combination of absolute or relative insulin deficiency and increased amounts of counterregulatory hormones. Glucose and lipid metabolism When insulin is deficient, the elevated levels of glucagon, catecholamines and cortisol will stimulate hepatic glucose production through increased glycogenolysis and enhanced gluconeogenesis4 (Fig. 1). Hypercortisolemia will result in increased proteolysis, thus providing amino acid precursors for gluconeogenesis. Low insulin and high catecholamine concentrations will reduce glucose uptake by peripheral tissues. The combination of elevated hepatic glucose production and decreased peripheral glucose use is the main pathogenic disturbance responsible for hyperglycemia in DKA and HHS. The hyperglycemia will lead to glycosuria, osmotic diuresis and dehydration. This will be associated with decreased kidney perfusion, particularly in HHS, that will result in decreased glucose clearance by the kidney and thus further exacerbation of the hyperglycemia. In DKA, the low insulin levels combined with increased levels of catecholamines, cortisol and growth hormone Continue reading >>

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  1. Milena

    The question of how soon ketosis starts during the dry fast is a very frequent one. Hence, I decided to start a thread to discuss my own experiments with pre-fast meals and how they might or might not effect ketosis.
    On June 12th, 2011 I started my weekly 36-hrs dry fast at 20:00. Prior to eat I had a dinner of all-you-can-eat sushi which mostly consisted of refined carbs (white rice) and protein (fish) with simple carbs being the dominant ingredient. The dinner ended at 18:00, after which I had a cup of coffee and a glass of water before commencing the fast.
    23 hour mark my ketons were at NEGATIVE
    25 hour mark my ketons were at between TRACE and SMALL
    34.5 hour mark my ketons were at between TRACE and SMALL
    36 hour mark my ketons were still between TRACE AND SMALL
    So the conclusion is that while we do go into ketosis at about 24 hours the conversion is a very slow process if the pre-fast meal is mainly refined carbs with some protein.
    My next fast will commence on Wed June 15th when I will have my pre-fast meal either low starch carbs (fruit and veggies) or all protein like fish and egg.

  2. Yuliya

    Yuliya replied the topic: Re: Dry Fast and Ketosis
    Milena, I am a little confused why you call rice 'simple carbs'. In fact rice is complex carbohydrate.
    Simple carbs are things like fruit, and also sugar.
    Complex carbohydrates are chains of three or more single sugar molecules linked together. Long chains of sugar molecules called starches serve as a storage form of energy in plants and when you eat those plants, your body breaks down the carbohydrates for your own energy needs. Even though complex carbohydrates are made from chains of sugars, they do not taste sweet. Complex carbohydrates are more difficult to digest than simple carbohydrates, because we need to break them down first.
    Simple carbohydrates are broken down quickly by the body to be used as energy.
    Simple carbohydrates come in 2 forms: refined sugars (extracted from fruits, grains, tubers, and sugar cane) and whole-food sugars (primarily sweet fruits). Both refined and whole-food simple sugars taste sweet to our tongue.
    May compassion to yourself and all beings guide you in your eating, fasting, and lifestyle choices.
    All my posts are based on my opinions and experiences only and are not intended to replace the advice of the licensed medical practitioner.

  3. Milena

    Milena replied the topic: Re: Dry Fast and Ketosis
    I actually meant to say "refined carbs" since it was white rice not brown. Will make that correction right now.
    May the Energy you free from digesting serves your Body and Spirit well!
    All my posts are based on my opinions and experiences only and are not intended to replace the advice of the licensed medical practitioner.

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What is DIABETIC KETOACIDOSIS? What does DIABETIC KETOACIDOSIS mean? DIABETIC KETOACIDOSIS meaning - DIABETIC KETOACIDOSIS definition - DIABETIC KETOACIDOSIS explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6Uu... Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion, and occasionally loss of consciousness. A person's breath may develop a specific smell. Onset of symptoms is usually rapid. In some cases people may not realize they previously had diabetes. DKA happens most often in those with type 1 diabetes, but can also occur in those with other types of diabetes under certain circumstances. Triggers may include infection, not taking insulin correctly, stroke, and certain medications such as steroids. DKA results from a shortage of insulin; in response the body switches to burning fatty acids which produces acidic ketone bodies. DKA is typically diagnosed when testing finds high b


GENERAL ketoacidosis is a high anion gap metabolic acidosis due to an excessive blood concentration of ketone bodies (keto-anions). ketone bodies (acetoacetate, beta-hydroxybutyrate, acetone) are released into the blood from the liver when hepatic lipid metabolism has changed to a state of increased ketogenesis. a relative or absolute insulin deficiency is present in all cases. CAUSES The three major types of ketosis are: (i) Starvation ketosis (ii) Alcoholic ketoacidosis (iii) Diabetic ketoacidosis STARVATION KETOSIS when hepatic glycogen stores are exhausted (eg after 12-24 hours of total fasting), the liver produces ketones to provide an energy substrate for peripheral tissues. ketoacidosis can appear after an overnight fast but it typically requires 3 to 14 days of starvation to reach maximal severity. typical keto-anion levels are only 1 to 2 mmol/l and this will usually not alter the anion gap. the acidosis even with quite prolonged fasting is only ever of mild to moderate severity with keto-anion levels up to a maximum of 3 to 5 mmol/l and plasma pH down to 7.3. ketone bodies also stimulate some insulin release from the islets. patients are usually not diabetic. ALCOHOLIC KE Continue reading >>

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