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What Does Ketoacidosis Affect

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Ketoacidosis: A Diabetes Complication

Ketoacidosis can affect both type 1 diabetes and type 2 diabetes patients. It's a possible short-term complication of diabetes, one caused by hyperglycemia—and one that can be avoided. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are two of the most serious complications of diabetes. These hyperglycemic emergencies continue to be important causes of mortality among persons with diabetes in spite of all of the advances in understanding diabetes. The annual incidence rate of DKA estimated from population-based studies ranges from 4.8 to 8 episodes per 1,000 patients with diabetes. Unfortunately, in the US, incidents of hospitalization due to DKA have increased. Currently, 4% to 9% of all hospital discharge summaries among patients with diabetes include DKA. The incidence of HHS is more difficult to determine because of lack of population studies but it is still high at around 15%. The prognosis of both conditions is substantially worsened at the extremes of age, and in the presence of coma and hypertension. Why and How Does Ketoacidosis Occur? The pathogenesis of DKA is more understood than HHS but both relate to the basic underlying reduction in the net e Continue reading >>

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  1. Tirth Patel

    Blood Sugar Control and Stabilization

    Infectious Diseases

    Health


    Medicine and Healthcare



    How does an infection affect blood sugar? I understand the disease process, however what is the true science behind it?




    1 Answer







    Any type of Infection causes a stress response in the body by increasing the amount of certain hormones such as cortisol and adrenaline. These hormones work against the action of insulin so production of glucose increases, which results in high blood sugar levels.
    In a person who does not have diabetes, extra insulin is produced to counter these effects, but this is not possible for someone with diabetes.
    When your blood sugar is high, the white blood cells in your body are unable to “mop up” bacteria because they cannot move around at their normal speed and do not reach the infection site quickly enough to engulf and kill the bacteria.

    So in a diabetic person, hyperglycemia persists and it can lead to ketoacidosis during infection or any other type of stress.

    221 Views · 2 Upvotes · Answer requested by Amy Boumaig








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