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What Do Exogenous Ketones Do?

Should I Be Taking Exogenous Ketones? (say What?!)

Should I Be Taking Exogenous Ketones? (say What?!)

Should I Be Taking Exogenous Ketones? Exogenous ketones were introduced in 2014… About the same time I really started diving into the health benefits of more fat in the diet. But let me back up here, you may not even be familiar with the word “exogenous” so let’s start there: Exogenous vs Endogenous Exogenous = Originates from a source external from the body Endogenous = Originates from a source internal to the body Exogenous ketone bodies are just ketone bodies that are ingested through a nutritional supplement. Ketone bodies produced in the liver are more properly referred to as endogenous ketone bodies. What does the science say? Although I don’t think eating a diet ample in healthy fat is a fad, I do know that when science proves something is beneficial for us, there is a company working relentlessly to manufacture a product related to that discovery that will fly off the shelves. Remember when resveratrol, found in red wine, was proven to be good for us? Supplement companies went crazy marketing pills and drinks with even just the tiniest hint of resveratrol in it promising anti-aging and weight loss. What about garcinia cambogia? Remember that? It was marketed as a product that stopped the body’s ability to make fat and reduce appetite. Very small studies were shown that garcinia cambogia slightly raised levels of serotonin in the brain…that was all. There was no proof that it inhibited fat production and actually suppressed the appetite enough to generate any weight loss. Most of the research put into exogenous ketone supplementation has been for the medical treatment of conditions such as cancer, epilepsy and Alzheimer’s/dementia. Any other research has been done for athletic performance. The goal is to see if the use of exogenous ketones provide Continue reading >>

Exogenous Ketones: The Truth You Need To Know!

Exogenous Ketones: The Truth You Need To Know!

Can Exogenous Ketones really give you the benefits of the actual ketogenic diet? Or is it just another marketing scam done correctly? Let’s dig in and find out! What are Exogenous Ketones and how do they work? What are Ketones? It only makes sense to start with what ketones are before we discuss about Exogenous Ketones. Ketones are a byproduct produced by your liver to be used as fuel when there’s a lack of glucose in your body. They’re always present in your blood and there are 3 types of Ketone bodies [1]: Acetoacetate (AcAc) 3 beta-hydroxybutyrate (3HB) Acetone These are called Endogenous ketones because they’re naturally produced by your body internally. 3 Times Your Body Produces more ketones: Fasting Long period of exercise Diabetes (pathological cause) Endogenous Ketones vs Exogenous Ketones: Exogenous ketones, on the other hand, are the same ketone bodies injected into your body in the form of Ketone supplements and drinks (Salts and Esters). Claim: Exogenous Ketones are being marketed as an instant way to put your body into Ketosis with or without the need to follow a Ketogenic diet. It’s important to remember that Ketogenic diet has been clinically proven to have many health benefits including weight loss. However, we’re discussing the external ketones that you can take in the form of supplements and drinks. What does Clinical research say about Exogenous Ketones? Research evidence: No evidence for the claim that Exogenous Ketone supplements can put you in instant ketosis. No human studies whatsoever. Some brands that talk about the benefits of their supplements seem to focus on the benefits of ketogenic diet rather than any evidence for the supplement. Here’s a study I found: Exogenous Ketones on Rats by Dr. Dominic D’Agostino In this study, t Continue reading >>

Exogenous Ketones: What They Are, Benefits Of Use And How They Work

Exogenous Ketones: What They Are, Benefits Of Use And How They Work

Exogenous ketones have become a popular nutritional supplement since their introduction in 2014. Like with any new supplement, though, there tends to be a lot of misinformation that you have to sift your way through to find the reliable data. So, this article does the hard work for you and gets right to what the true benefits and drawbacks of exogenous ketones are. We also cover what forms of ketones to consider, how they function in the body, and their role in future research. What Are Ketones? Our bodies use ketones via our mitochondria to generate energy. They are an alternative fuel source to glucose. Ketones are simple compounds because of their small molecular structure and weight. Specifically, they are organic (carbon-based) compounds that contain a central carbon atom double-bonded to an oxygen atom and two carbon-containing substituents, denoted by “R” (see chemical structure below). In humans, there are 3 different ketones produced by the mitochondria of the liver. These are also often referred to as ketone bodies. The three ketones are: Acetone Acetoacetic Acid Beta-Hydroxybutyric Acid (also known Beta Hydroxybuyrate or BHB). Other chemical names include 3-hydroxybutyric acid or 3-hydroxybutyrate. BHB is not technically a ketone since it contains a reactive OH-group in place of where a double-bonded oxygen normally would be as you can see in the diagram below. Yet, BHB still functions like a ketone in the body and converts into energy much like acetoacetate and acetone. This happens via the acetoacetate and acetyl-CoA pathway. Note that acetone conversion to acetyl-CoA is not efficient due to the need to convert acetone to acetoacetate via decarboxylation. However, BHB still functions like a ketone in the body and can be converted to energy (via acetoace Continue reading >>

Ketogenic Supplements Reviews Fast & Safe Keto Products For Weight Loss

Ketogenic Supplements Reviews Fast & Safe Keto Products For Weight Loss

Ketogenic supplements are taking the world by storm and the right product can steady the balance of fats that your body needs to get your body into that state of ketosis. Those of you who have tried this form of weight loss before are probably more than aware of how hard it can be to first get your body to adapt to such a dramatic change in your daily intake of food, let alone without the help of a single exogenous ketone supplement. And the situation isn’t made any easier if you use a poor quality ketosis supplement because the wrong product may actually do you more harm than good. Bad quality ketosis supplements, have proven to lead to side-effects such as constipation and increased levels of cholesterol and triglycerides in men and women may also experience amenorrhea or other disruptions to the menstrual cycle. This is why it is really important to know what combination of compounds you are consuming, particularly while you are on this very strict diet, because the wrong balance can really mess with you in the long term. DO YOUR RESEARCH. I can't stress this point enough. This lifestyle change isn't for the faint hearted and you can't just wing it. It's a calculated exercise, which can lead to so many benefits. Check out the rest of this article so you can get up to speed, on how everything works and what powder or pill are actually out there and when you're finished go deeper and read our articles on the science behind this fascinating and our reviews on the best mix of exogenous ketone supplements out there in the market. Because without the knowledge and the right information, you'll never reach your goals and you may as well just keep eating that mash potato for dinner and club sandwich for lunch. Believe me, I stumbled onto this trend before it even blew up a Continue reading >>

Exogenous Ketones Pros And Cons

Exogenous Ketones Pros And Cons

What Are Exogenous Ketones? Exogenous Ketones (EK for short) are ketone supplements and by definition, a supplement is a thing added to something else in order to complete or enhance it. Think about it like building muscle, good supplements can enhance your results, but if you don’t eat right and exercise, supplements are just useless. You can’t just sit on the couch to watch TV, eat potato chips all day and drink some supplements and expect to gain muscle. A supplement is not a miracle. It’s just an addition and before you add it to your diet, you need to get the basic right first, which is dieting and exercise in the case of building muscles. The supplements are not going to lift the heavy weights for you. You do! Back to the case of EK. If you cheat on your keto diet and eat a ton of carbs, and you want to use EK as a way to feel better and less guilty about it, it’s probably not a smart choice because EK won’t do anything for you (more on this later). However, if you are eating LCHF and somehow you’re not feeling your best, EK can be helpful and we will explain more below. Our Approach We own and manage a few growing Keto Facebook groups with tens of thousands of members and we often see the exogenous ketones topic comes up. We have seen a lot of confusion and criticism as well as support from our members. Most of the complaints are normally because of the expensive price of some products, the lack of understanding about what the product is and what it does to your body or because some sellers/promoters try to bend the truth to get you buy their products or recruit you into their multi level marketing team. We recently ran a survey in our private group and asked people if they have used EK before and if it worked for them. Here’s the result: Many peopl Continue reading >>

What Are Exogenous Ketones: Can You Eat Carbs And Stay Keto?

What Are Exogenous Ketones: Can You Eat Carbs And Stay Keto?

It was a few years ago when I found out, i’ve been lied to. Everyone out there telling us that we need to be eating a lot of carbs and to stay away from fats. Anyways, what are exogenous ketones? Do they really help with fat-adaptation? Even those who went out of their way to receive a “nutrition degree” is falsely educated on what it really means to stay healthy. I figured, screw it, I’m gonna do my own experiments and see what suits me best. I did the IIFYM (if it fits your macros) diet, a low fat high carb diet, and of course, the ketogenic diet. Being someone who exercises a lot, I was told by countless people that I needed carbs if I wanted to perform optimally. They couldn’t be any further from the truth. You’re probably in the same position I was in a couple years ago. You had this belief that the only way to make the gains in the gym, drop body fat, and look sexy is by eating as low fat as possible while eating carbs to “fuel your workouts”. Because fats make you fat, right? Wrong. While every diet regimen out there can definitely make you lose weight, some diets can do some serious damage to your metabolism and hormonal function. I used to follow a strict low fat high carb diet. And it worked, I had a six pack and looked good with my shirt off. But my testosterone levels were complete shit. I had no energy to do anything and I felt like a plank of wood. Lifeless. It wasn’t until I began to follow a low carb high fat ketogenic diet did I start to have awesome energy levels and STILL look physically great. I realized that being in a state of ketosis gave me the most energy and mental clarity. What Is Ketosis? Ketosis is a State where your body’s energy comes from ketones. This is achieved by restricting carbohydrates. By cutting carbs out, you Continue reading >>

To Ketone Or Not To Ketone: Mineral Salts

To Ketone Or Not To Ketone: Mineral Salts

Let me preface this article by stating that I am not affiliated, do not know any of these companies directly, and haven’t tested them in any way. Rather, due to the recent explosion of ketone supplements on the market, I wanted to cover the importance of considering mineral salt content of these supplements. Exogenous ketones are becoming more popular than ever as advancements in scientific research continue to show how they work to improve both health and performance. At first, the only options for delivering exogenous ketones were unpalatable ketone esters; however, now exogenous ketones can be taken in the form of ketone mineral salts that are easily blended and palatable in water. Making ketone mineral salts involves combining beta hydroxybutyrate (BHB) with mineral salts such as sodium, calcium, magnesium, or potassium. Before considering whether ketone supplements are a good option, most people immediately look at the salt load, and rightfully so. It is important to take into account the nutritional and health impact of not only the BHB, but to consider the minerals that are used to make the product. Although there is more current evidence on the effectiveness of ketone esters , ketone salt supplementation has the potential to provide additional benefits through the extra electrolytes/nutrients that are required to make the ketones. While ketone esters are expensive due to the manufacturing process involved in making them, ketone salts might be a more convenient option for both inducing a state of ketosis and elevating blood ketone levels for various reasons we will discuss separately. Let’s take a look at some of the facts and misconceptions about three of the minerals used to make ketone mineral salts: sodium, calcium, and magnesium. (Potassium is very hygro Continue reading >>

For The Love Of Exogenous Ketones!

For The Love Of Exogenous Ketones!

You read that correctly. I love ketones and I am actively pursuing ways to increase my bodies ability to produce them through the use of exogenous ketone supplements. Ketones are a dirty word in the world of diabetes because of the confusion surrounding their appearance as the harbinger of doom through DKA (diabetic ketoacidosis). Unfortunately many healthcare providers actively discourage their diabetic patients from attempting to achieve nutritional ketosis because they don’t fully understand the difference between nutritional ketosis and DKA. That difference is NOT the focus of this post, other than to establish the fact that there IS a difference. It’s important to note that the means of detecting DKA is typically the presence of ketones in the blood. Adding them through exogenous supplementation or nutritional ketosis is useful (I would even argue beneficial), but not without some risk. In case of insulin deficiency (bad pump site, occlusion, skipped dose etc) while in ketosis one would be without the means to clearly identify DKA. You’d only be able to guess based on blood glucose level to infer how insulin deficient you are. The risk can be mitigated through vigilance and attention to insulin dosing but shouldn’t be taken lightly. I’ve recently started using exogenous ketones to help put me into nutritional ketosis more readily and I wanted to report the initial findings since I’ve been asked about them so many times. Up till this point I didn’t feel compelled to spend the time and money on exogenous ketone supplements–which are not cheap! I took the plunge and got some delicious, chocolate-flavored betahydroxybutyrate or (BHB) for short. I am not going to attempt to get into the science behind the impacts of BHB on my blood sugar, energy and meta Continue reading >>

Of The Keto Diet?

Of The Keto Diet?

There are many awesome benefits that come with adopting a low-carb ketogenic diet, such as weight loss, decreased cravings and even possibly reduce disease risks. With that being said, it’s also good to talk about possible ketosis side-effects when ingesting these specific ketone supplements, so you know fully what to expect when you get started on this mission. If you’ve already heard about some of the side-effects that come with this special diet and are starting to freak out, don’t panic. We’re going to break down everything you need to know when it comes to what your body will experience when using these supplements for the first time. It’s important to remember, not everyone experiences side-effects when starting a ketogenic diet and thankfully, the symptoms are all very temporary and it can pass very quickly. It varies with the individual, but just to make sure all your bases are covered, we’re going to break down each possible side effect that you could possibly experience. 1. Flu Symptoms Within the first 2-4 days of beginning this diet, a common side-effect is known as the “ketosis flu” or “induction flu” because it mimics the symptoms of the actual flu. This means you might experience: Headaches Lethargy Lack of motivation Brain fog or confusion Irritability​ Although these symptoms typically go away completely within a few days, they are also completely avoidable if you stay very hydrated and increase your salt intake and like always, be sure you're eating enough fat. 2. Dizzyness & Drowsiness​ As you start dumping water, you'll lose minerals such as salt, potassium and magnesium. Having lower levels of these minerals will make you tired, lightheaded or dizzy. You may also experience muscle cramps, headaches and skin itchiness. Fatigue Continue reading >>

Will Taking Exogenous Ketones Stop Fat Loss?

Will Taking Exogenous Ketones Stop Fat Loss?

Would you like to lose some fat? A ketogenic diet is a pretty good tool to help you reach your goal. You can use exogenous ketones which have been a popular way to help get people into ketosis and comply with the transition from eating carbs to eating fats. Once in ketosis, use real food to stay there. Sounds easy, right? Unfortunately, some bro science complicating this topic has been surfacing which must be quashed. People are claiming that exogenous ketones are stopping the fat burning that people are seeking. The same exogenous ketones that help a lot of people experience ketosis and make getting into and staying in ketosis much easier, which makes the fat loss so much easier. SAD! This is how the logic follows from people who don’t really understand physics but like to quote laws of physics to sound fancy like they know how the human body works: Exogenous ketones contain energy. Body fat is stored energy. Therefore, if you consume any energy, you can’t use any stored energy. That’s not really how the body works. At all. By that same rationale, if you were to eat any dietary fat (or any food), then you wouldn’t be able to burn any fat. Unless every single person who has ever lost fat has only done so by doing a water fast, I think this argument and concern is pretty invalid. So before we get further: NO, exogenous ketones do not stop fat burning. Fat loss and fat gain are a little more complicated than people think. I personally don’t believe in the strict calorie in, calorie out model that some people who misunderstand conservation of energy do. Your body is not a bomb calorimeter, so stop telling me that you need to intake a deficit of x amount of calories for y amount of fat loss, people who clearly don’t understand physics (or the human endocrine sys Continue reading >>

The Keto Diet Podcast Ep. #041: Responsible Exogenous Ketone Usage

The Keto Diet Podcast Ep. #041: Responsible Exogenous Ketone Usage

Interview with Dr. Gustin, a board certified sports physician and functional medicine practitioner, chatting about exogenous ketones – what they are, how they work, when and how to use exogenous ketones, ingredients in exogenous ketones, problems with the exogenous ketone market, and so much more. I’ll be the first to admit that I never, ever, thought in a million years that I’d be supplementing with exogenous ketones, let alone sharing them with you. But meeting many of you on the book tour, and speaking to individuals that have supplemented with ketones to compliment their ketogenic diet and help make the transition easier, I owed it to our crew to do some additional research, and here we are. Today, I interviewed the down-to-earth owner of Perfect Keto, asking him about all things exogenous ketones. From what they are, signs that you need them, signs that you don’t, the difference in products, ingredients used in exogenous ketones, whether they’re FODMAP or not, diet culture surrounding the product, accessibility issues, how exogenous ketones are digested, whether they lead to limited fat burn, and more. No stone left unturned. For podcast transcript, scroll down. SHOW NOTES + LINKS Subscribe on iTunes or your favorite podcast app Check out more from Dr. Gustin here and here TIMESTAMPS Problems with exogenous ketone supplementation (24:20) Ketone esters vs. salts (36:46) Exogenous ketone misconceptions (48:10) PARTNERS OF THE KETO DIET PODCAST The podcast is partnered with Wolfe Clinic Royal Flora, my choice in soil-based probiotics. Get 20% off your soil-based probiotics with the coupon code GUT at checkout. Thrive Market 35% savings – get an instant 35% off your favorite premium organic products. All you have to do is enter your email address, and the d Continue reading >>

Exogenous Ketones For Fat Burn

Exogenous Ketones For Fat Burn

OVERVIEW Exogenous ketones are the newest scientific breakthrough in the world of health and wellness, making the job of achieving ketosis, the state in which the body is burning fat/ketones as fuel rather than glucose, much easier. They come in powder form and are ingested exogenously (a fancy word for outside the body). Exogenous ketones are comprised of beta-hydroxybutyrate salts, which flood your bloodstream with ketones and put the body in ketosis within 30-60 minutes. This means that you can reap all the amazing health benefits of being in ketosis in a simple and effective way (just mix the exogenous ketones with water & drink!). Research is now linking exogenous ketones to a multitude of benefits, including more efficient weight loss, athletic performance enhancement, cancer prevention, cognitive improvement, neuroprotection and anti-inflammatory properties. (See research links below.) In addition, exogenous ketones are an extremely useful tool to easily transition to the ketogenic diet. When taken daily, they can reduce carb/sugar cravings, turn on your fat burners, give you more energy, and keep "low-carb flu" at bay. So bottom line, exogenous ketones are perfect for anyone looking to improve their health and wellbeing. WHY USE THEM Reason #1 - Fat Burning Exogenous ketones for fat burn. Taking exogenous ketones will get you into ketosis quickly. Once your body is done using the exogenous ketones you ingested as fuel, then it will start looking for other places to get ketones from. And lucky for you, ketones are made from the fat stored in your body! So as your body produces more of these ketones as fuel, you end up burning fat. Reason #2 - Energy Our bodies use ketones via our mitochondria to generate energy. They are an alternative fuel source to glucose and Continue reading >>

How To Use Exogenous Ketones

How To Use Exogenous Ketones

Exogenous Ketones were introduced in 2014, about the same time as I was recovering from having my daughter, and therefore very concerned about weight loss. But let’s back up for a bit, because if you’re here reading about Exogenous Ketones, and how to drink ketones for weight loss, let’s start at the beginning so you have a firm foundation to build if you do decided to take a ketone supplement for weight loss. First of all, Exogenous Ketones (we’ll get to exactly what those are in just a sec…hang in there) were introduced as the Ketogenic Diet started gaining popularity among the health and fitness community, as well as with the scientific community. Why? Well, it’s all about health. For so long, doctors and researchers have preached the benefits of a low-fat diet to prevent and correct all sort of things like heart disease, high cholesterol, obesity, etc. But….they may have been wrong. I am not a doctor, and do not have a medical degree, but I’ve done my homework, and I’ve lived (and am currently living) a ketogenic lifestyle. So I’ve done this, I’ve read loads and loads about it, and I’ve even been able to help many of my friends use the things I’ve learned to lead healthier lives. But, as with anything concerning your health, please make sure you have a discussion with your doctor before making a drastic change. Related: I lost 23 pounds in 60 days of Keto. Here’s how. Ok, legal stuff over, here’s what a Ketogenic Diet is: A Ketogenic Diet, also know as the Keto Diet, is a very high fat, very low carb, moderate protein diet that is very popular because it can cause you to lose body fat very fast, and study after study after study has linked Keto with benefits against cancer, diabetes, Alzheimer’s, epilepsy, and more. Eating Ketogenical Continue reading >>

Beware Exogenous Ketones

Beware Exogenous Ketones

There are three ways to raise blood levels of ketones and obtain the potential benefits from them: physiological ketosis via strict carbohydrate limitation or fasting; supplementation of medium-chain triglyceride (MCT) oils that are metabolized in the liver to ketones; and actually taking the ketone, beta-hydroxybutyrate. In this Undoctored Blog post, I’d like to discuss exogenous ketones. While fascinating with potential for substantial health benefits, there are some very real dangers with the current products on the market, so much that I have reported two of the products to the FDA. This is part of the expanded health discussion I begin in the new Undoctored book, Undoctored: Why Health Care Has Failed You and How You Can Become Smarter Than Your Doctor, with a comprehensive discussion of all aspects of ketosis in the Undoctored Inner Circle Advanced Concepts, the membership site for the truly serious Undoctored follower. You will also find a brief conversation about what I call “Assisted Fasting” using MCT oils in this video. Early research on supplemental exogenous ketones demonstrated fascinating effects, such as protection from hypoglycemia (as ketones are an alternative source of brain energy), protection from seizures (including in Navy seals who breathe high levels of oxygen that can cause fatal underwater seizures), and improved aerobic performance in trained athletes. More recent research has uncovered or confirmed additional effects of supplemental exogenous ketones: Improved endurance and aerobic performance in athletes—-Indeed, many professional athletes are supplementing exogenous ketones. Modest increase in muscle growth with exercise; less muscle lost with weight loss Greater fat burning (oxidation) during exercise, less reliance on glycogen/s Continue reading >>

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Four New, Cutting-edge Ways To Easily Shift Your Body Into Fat-burning Mode & Ketosis.

Great article. You actually answered my question as to the ratio of the 3 BHB salts which is quite helpful for me. For me, I had Keto O/S and found it quite good – my favorite was the chocolate swirl. But it was and is very expensive. Only 15-20 servings and would break the bank. So I turned to KetoCaNa and I’ve tried two flavours. Both of them were so salty that I almost threw up every time. Like flavoured sea water. Also only 15 serving per bottle. Then I turned to Ketond which is okay – Tigers Blood and Caramel Macchiato. What I like about Ketond is that it has a full 30 servings and is very transparent with it’s ingredients. It’s also the same price as Keto OS but you get 30 servings. But still, not the best taste. So in the end, I ordered 1kg of pure BHB Magnesium from a supplier in China and I will be developing my own Ketone product with 30 servings as a lower price than all the competitors, and with more Magnesium, and Calcium in it than Sodium so that it tastes the best and actually helps with weight loss (which Magnesium is proven to do at the right amount). What the companies don’t tell you is that actually Sodium BHB is the cheapest, then Calcium BHB and then Magnesium BHB to source so I would be interested in knowing if what you wrote is actually true or just an excuse to make the product cheaper. Probably a mix of both. So I have 2 questions Ben: 1. If you had to split the 11.7g of BHB into Sodium, Ca, and Mg, what ratio would you do for the best health results and potential weight loss? The current products on the market are about an 80/12/8 split. I would think it should be the other way around. 2. When I develop my own product and sell it, would you be up for sampling it and reviewing it on your website here? What flavours do you like/would Continue reading >>

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