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What Causes Acid Ketosis?

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Donation Option www.paypal.me/ickedmel Personal Email: [email protected] Business Email: [email protected] *Follow My Social Media* FACEBOOK: https://www.facebook.com/iCkEdMeL/ TWITTER: https://twitter.com/MelvinCedeno https://www.instagram.com/ickedmel/ Subscribe to both of my channels iCkEdMeL (Main Channel) http://bit.ly/2kiMqZL iCkEdMeL Live (Alternate / Live Stream) http://bit.ly/2LsoLEN Support the channel by using my affiliate Link @ no cost http://amzn.to/2Dqp7Yy I earn a small commission CONTENT DISCLAIMER Due to the social nature of this channel, videos may contain content copyrighted by another entity or person. We claim no copyright to said content. Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. This video and our YouTube channel, in general, may contain copyrighted works that were not specifically authorized to be used by the copyrighted holders(s), but which we believe in good faith or protected by federal law and the Fair Use Doctrine for one or more of the reasons noted above. If you have a complaint about something or find your content is being used incorrectly. PLEASE CONTACT OUR CHANNEL PRIOR TO MAKING A COPYRIGHT CLAIM. Any infringement was not done intentionally and any alleged infringement will be rectified to all parties satisfaction. #iCkEdMeL

Ketosis

There is a lot of confusion about the term ketosis among medical professionals as well as laypeople. It is important to understand when and why nutritional ketosis occurs, and why it should not be confused with the metabolic disorder we call ketoacidosis. Ketosis is a metabolic state where the liver produces small organic molecules called ketone bodies. Most cells in the body can use ketone bodies as a source of energy. When there is a limited supply of external energy sources, such as during prolonged fasting or carbohydrate restriction, ketone bodies can provide energy for most organs. In this situation, ketosis can be regarded as a reasonable, adaptive physiologic response that is essential for life, enabling us to survive periods of famine. Nutritional ketosis should not be confused with ketoacidosis, a metabolic condition where the blood becomes acidic as a result of the accumulation of ketone bodies. Ketoacidosis can have serious consequences and may need urgent medical treatment. The most common forms are diabetic ketoacidosis and alcoholic ketoacidosis. What Is Ketosis? The human body can be regarded as a biologic machine. Machines need energy to operate. Some use gasoline, Continue reading >>

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  1. Anonymous

    Hi everyone
    Following some advice on the approaches to managing blood glucose on this forum, I decided to try a very low carbohydrate diet, where my intake didn't go above about 70 to 80 grams per day. I am on Metformin which I take morning and night. It is not the SR version.
    At first, I did feel much better as my blood glucose levels started to come down. Then, something started to happen to me. Following my breakfast of cheese and meats, I go to work or go out to play and at about 10am, I started to slump. In fact I felt quite unwell on a regular basis, and this always happened mid-morning.
    Recently, I travelled to Ashford in Kent for a meeting with my boss and when I arrived at Ashford Station, I just had to sit down. I now recognise what was happening to me - I was hypoglycemic.
    At the kiosk, I bought a small coffee and a sugary snack (a flapjack). Within minutes of eating it, I felt much better and had more energy. In fact, I felt fine. Even my boss noticed, as she noticed I looked pasty when I arrived, but had more colour in my cheeks later on.
    I have tested myself in this state, and get a reading of about 4.5 mmol/l. I wake up with a high BG level, but with the carb-free breakfast and the metformin, this level drops markedly.
    This means that a change of strategy may be called for and I am thinking of two options:
    1. remaining on the same lo carb diet with no metformin in the morning; or,
    2. maintaining the same medication regime, but upping my carbs slightly and, maybe, have a snack if I need to, and having the bulk of the carbs in the morning and easing off by lunchtime.
    I do find that almost completely eliminating carbs from my diet can make for a quite boring eating regime anyway, but I would appreciate some feedback.
    Many thanks
    Dave

  2. hanadr

    Dave,
    I'd go with the reduced Metformin option, since I always like to minimise medicines. Also add in a LITTLE carb in the morning. Perhaps a piece of fruit?
    I personally eat much less than 70/80grams carb per day and take 2 x 500mg Metformin. I don't seem to make ketones though.
    Hana

  3. borofergie

    Eating a low-carb diet will not make you hypoglycemic (unless you are also taking more powerful medication than metformin). In fact, the reverse is true, as you start to produce ketones to reduce your brain's glucose requirements your blood glucose levels will stabalise.
    What you describe sounds like a "false hypo", which is a withdrawal symptom, as your body gets used to operating at (more) normal blood glucose levels. You should embrace it, it's a sign that you're starting to get your diabetes under proper control.
    You didn't mention how long you've been on a low-carb diet, but it takes at least a coupe of weeks to adjust first time you try it, during which period you'll also experience the symptoms you've described above, often known as the "low-carb flu".
    I think that sweating it out is a better idea than increasing your carbohydrate intake, but that's your decision. Good luck.
    S.

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Is Ketosis Dangerous?

You may have heard from your doctor that ketosis is a life-threatening condition. If so, your doctor is confusing diabetic ketoacidosis (DKA) with nutritional ketosis, or keto-adaptation. First, some semantics. Our body can produce, from fat and some amino acids, three ketone bodies (a “ketone” refers to the chemical structure where oxygen is double-bonded to carbon sandwiched between at least 2 other carbons). These ketone bodies we produce are: acetone, acetoacetone, and beta-hydroxybutyrate (B-OHB). [For anyone who is interested, they are the 3 most right structures on the figure, below.] Why do we make ketones? For starters, it’s a vital evolutionary advantage. Our brain can only function with glucose and ketones. Since we can’t store more than about 24 hours’ worth of glucose, we would all die of hypoglycemia if ever forced to fast for more than a day. Fortunately, our liver can take fat and select amino acids (the building blocks of proteins) and turn them into ketones, first and foremost to feed our brains. Hence, our body’s ability to produce ketones is required for basic survival. What is diabetic ketoacidosis? When diabetics (usually Type I diabetics, but some Continue reading >>

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  1. blurfocus

    Your first, best, and cheapest option is not to use them.
    Ketostix do not measure what many people expect that they do.
    Ketostix only measure excess levels of acetoacetate, which is not the type of ketones that correlate with nutritional ketosis.
    Ketostix may show negative ketones when your blood ketones are high and then may show positive ketones when your blood ketones are low.
    Misinterpretation of what they show is one of the most common unnecessary causes of keto anxiety and wasted time. You can be perfectly successful on a ketogenic or low-carb diet without ever measuring ketones.
    Many people are already overwhelmed with learning about keto diets. Adding another layer of unnecessary complexity doesn't help the matter. Often, people are most successful on keto when they treat it as a lifestyle and not a diet. Obsessively measuring ketones can be at odds with attempting to live a keto lifestyle.
    If you decide to use Ketostix anyway, please be kind to those who answer questions here by not submitting a question that begins with I know that Ketostix are unreliable, but ...
    If you consume few enough carbohydrates and avoid excessive intake of protein, you can trust that your liver will be producing ketones within a single day. That is how human metabolism works.
    If you consume too many carbs, you will be kicked out of ketosis temporarily. However, if you once again restrict carbs, you will go right back into ketosis within 24 hours. This is because the liver can store only 100 grams of glycogen. If you restrict carbs, the liver will run out of glycogen within a day and begin burning fat instead. The liver produces ketones as a side effect of burning fat.
    As an example of how Ketostix can be misleading, it is possible to eat a high-carbohydrate meal followed by a positive Ketostix result. You may think that you cheated the system, but you didn't. It takes time for excess ketones to appear in urine. Ketostix are showing you what happened in the past before you cheated.
    If you have the time and really want to know why Ketostix will not tell you much, read pages 164 and 165 of The Art and Science of Low Carbohydrate Living by Volek and Phinney. This is the section headed by Ketones: To Measure or Not.
    If you do not have this book, read this summary:
    http://ketopia.com/why-you-need-to-stop-worrying-about-the-color-of-your-ketostix/
    Ketostix were designed to help diabetics avoid ketoacidosis which is a dangerous condition involving very high blood sugar and very high serum ketones. If you have near normal blood sugar and serum ketone levels consistent with nutritional ketosis, you don't need to worry about this.
    Ketostix only measure excess levels of acetoacetate, which is not the type of ketones that correlate with nutritional ketosis.
    The ketones that correlate with nutritional ketosis are known as beta-hydroxybutyrate. This type can be measured only with a blood ketone meter.
    There is a built-in time lag. Ketostix are measuring what has happened in the past since it takes a while for the kidneys to produce urine.
    Exercise can influence how many excess ketones are excreted.
    You can be in nutritional ketosis even when Ketostix show no excess acetoacetate. In the keto-adapted state, very little acetoacetate ketones will be excreted in urine even though blood ketones may be high.
    Note that it takes a period of four to six weeks of being in ketosis every day in order to become keto-adapted. Someone who is keto-adapted has adapted to using fat as the primary fuel for muscles and various organs. The keto-adapted brain uses ketones in place of glucose for most of its energy needs. When keto-adapted, most acetoacetate is not excreted. Instead, muscles convert it to beta-hydroxybutyrate and return it to the blood for use by the brain.
    If after all of this, you still want to use Ketostix because you bought them and cannot bring yourself to throw them away or because they are comforting in some way, here is how they may be useful.
    When you are first starting a low-carb or keto diet and transitioning into ketosis from a moderate to high-carb diet, Ketostix will confirm that your body has in fact done what biology says that it must do. It will show that your liver has begun producing ketones.
    Once you are a few days into the diet, you can give them away to a keto newbie or toss them. Note that Ketostix will eventually expire, especially if you keep them in a moist environment like a bathroom.
    If you have a medical condition that makes monitoring blood ketone levels necessary or if you are a numbers geek with spending money, you may be interested in purchasing a ketone blood meter and test strips for measuring beta hydroxybutyrate in your blood. The test strips cost somewhere between $2 and $5 per strip.
    There are a few meters to choose from.
    Precision Xtra - https://www.abbottdiabetescare.com/products/patient/pxtra-overview.html
    Nova Max Plus - http://www.novacares.com/nova-max-plus/
    CardioChek Home - http://www.healthchecksystems.com/CardioChek.cfm#home
    Most use one of the first two listed (Precision Xtra or Nova Max Plus). Some say that the Precision Xtra is the more accurate of the two. I've found that readings from these two track fairly closely with each other. The Nova Max Plus has cheaper test strips.
    To detect nutritional ketosis, look for a reading between 0.5 and 5.0 mmol / liter. Some experts recommend aiming for a level of 1.0 to 5.0 mmol / liter.
    Another option is the Ketonix Sport breath meter. This meter measures acetate in the breath. It does not require test strips.
    Acetate forms when acetoacetate spontaneously breaks down to acetate. According to Volek and Phinney (page 165 of The Art and Science of Low Carbohydrate Living), it should be linearly correlated with blood ketones. In practice, it is not as accurate as the blood meters in part because it is difficult to breathe in the same way every time you test.
    Ketonix Sport (order direct from Sweden) - https://www.ketonix.com/index.php/product/sport
    Again, remember that you can be perfectly successful on a ketogenic or low-carb diet without ever measuring ketones whether in urine, blood, or breath.
    In the final analysis, ketone concentrations are what they are. Chasing ketone concentrations often becomes as unnecessary and distracting as Ketostix. Unless you are treating epilepsy, cancer, or other medical condition, the concentration of ketones do not matter too much. You can achieve weight loss and a sense of well-being even with lower levels of ketones.
    Focus on how you feel, not on the number. Use ketone meters for interest and experimentation, but don't let the results stress you out.
    tl;dr never, unless you have read and understood this post, yet still want to use them anyway
    [If anyone has any suggestions for improving this post or correcting misinformation, let me know. I'll correct this and re-post it once in a while]

  2. anbeav

    Hallelujah!!
    tl;dr never
    If you want to do it for experimentation, go for it but please spare the rest of us the unnecessary ketosis anxiety
    edits: In addition to false negatives, ketostix commonly show false positives as in when people eat a high carb meal and think they cheated biology. Also I might remove the bit about using ketostix to monitor keto-adaptation, just asking for more posts about the issue. Also I might emphasize that people seem to already be overwhelmed with keto when starting and adding another layer of unnecessary complexity doesn't help the matter. People always talk about lifestyle, live a lifestyle and IMO living a lifestyle certainly shouldn't have to include measuring. Lastly, ketone concentrations are what they are. If you want to measure with a blood or breath meter, they are what they are and chasing ketone concentrations often becomes as unnecessary as ketostix. Unless someone has a medical condition for which a particular concentration is required for management, focus on how you feel not the number. Use the meter for interest and experimentation, but don't let it stress you out.

  3. blurfocus

    Thanks. I have incorporated your feedback.

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Donation Option www.paypal.me/ickedmel Personal Email: [email protected] Business Email: [email protected] *Follow My Social Media* FACEBOOK: https://www.facebook.com/iCkEdMeL/ TWITTER: https://twitter.com/MelvinCedeno https://www.instagram.com/ickedmel/ Subscribe to both of my channels iCkEdMeL (Main Channel) http://bit.ly/2kiMqZL iCkEdMeL Live (Alternate / Live Stream) http://bit.ly/2LsoLEN Support the channel by using my affiliate Link @ no cost http://amzn.to/2Dqp7Yy I earn a small commission CONTENT DISCLAIMER Due to the social nature of this channel, videos may contain content copyrighted by another entity or person. We claim no copyright to said content. Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. This video and our YouTube channel, in general, may contain copyrighted works that were not specifically authorized to be used by the copyrighted holders(s), but which we believe in good faith or protected by federal law and the Fair Use Doctrine for one or more of the reasons noted above. If you have a complaint about something or find your content is being used incorrectly. PLEASE CONTACT OUR CHANNEL PRIOR TO MAKING A COPYRIGHT CLAIM. Any infringement was not done intentionally and any alleged infringement will be rectified to all parties satisfaction. #iCkEdMeL

Ketosis: What Is Ketosis?

Ketosis is a normal metabolic process. When the body does not have enough glucose for energy, it burns stored fats instead; this results in a build-up of acids called ketones within the body. Some people encourage ketosis by following a diet called the ketogenic or low-carb diet. The aim of the diet is to try and burn unwanted fat by forcing the body to rely on fat for energy, rather than carbohydrates. Ketosis is also commonly observed in patients with diabetes, as the process can occur if the body does not have enough insulin or is not using insulin correctly. Problems associated with extreme levels of ketosis are more likely to develop in patients with type 1 diabetes compared with type 2 diabetes patients. Ketosis occurs when the body does not have sufficient access to its primary fuel source, glucose. Ketosis describes a condition where fat stores are broken down to produce energy, which also produces ketones, a type of acid. As ketone levels rise, the acidity of the blood also increases, leading to ketoacidosis, a serious condition that can prove fatal. People with type 1 diabetes are more likely to develop ketoacidosis, for which emergency medical treatment is required to av Continue reading >>

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Popular Questions

  1. * why k is given

    * why k is given in DKA?

    HI FORUM MEMBERS...
    please clear this doubt..
    FA 2007 PAGE 271.
    in diabetic ketoacidosis,we have hyperkalemia,(but depleted intracellular k)
    why do we give potassium along with fluids n insulin in the management??
    please explain....

  2. bdj - 02/28/08 01:44

    because this is pseudohyperkalemia what is happening is that H+ ions are driving K+ outside of the cell, as soon as you start correcting the acidosis K+ will go back in and then you're in trouble if you don't add K+. Also K+ should be added 50/50 as KCL/K2PO4 because you will also consume PO- and if you don't replace it you are left with...no ATP
    GL

  3. harsh - 02/28/08 07:02

    the bdj expalnation is true

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