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Type 2 Diabetes Mellitus: Update On Diagnosis, Pathophysiology, And Treatment

Type 2 Diabetes Mellitus: Update on Diagnosis, Pathophysiology, and Treatment Division of Diabetes, Endocrinology, and Metabolism, Cornell University Medical College, New York, New York 10021 Search for other works by this author on: Division of Diabetes, Endocrinology, and Metabolism, Cornell University Medical College, New York, New York 10021 Search for other works by this author on: The Journal of Clinical Endocrinology & Metabolism, Volume 84, Issue 4, 1 April 1999, Pages 11651171, Richard J. Mahler, Michael L. Adler; Type 2 Diabetes Mellitus: Update on Diagnosis, Pathophysiology, and Treatment, The Journal of Clinical Endocrinology & Metabolism, Volume 84, Issue 4, 1 April 1999, Pages 11651171, SIXTEEN million individuals in the United States with type 2 diabetes mellitus and an additional 3040 million with impaired glucose tolerance result in health care costs exceeding 100 billion dollars annually ( 1 ). Treatment is predominantly directed at microvascular and macrovascular complications ( 2 ). In type 1 diabetes mellitus the relationship between glycemic control and microvascular complications has been well established ( 3 ). The relationship between tight glycemic contro Continue reading >>

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Popular Questions

  1. chocoholic

    Please may I ask if anyone knows if there is an alternative to Metformin? I have a 73-year-old friend who is a Type 2 and Metformin is making his life a misery. His stomach is constantly upset. I think he takes Gliclazide too but his readings seem constantly too high and I am worried for him.This past week he has had a flu type virus that has sent his readings up to sitting around 23 and I persuaded him those levels were becoming dangerously high, so he did phone for advice and a doctor met him at the out-of-hours clinic at the hospital but promptly sent him home with instructions just to double his Metformin.Now his stomach is so upset he cannot even leave the house.
    Personally, I think he'd be better off on insulin now as even on a good day his readings only seem to sit around the 9 mark and I feel he'll be heading for complications if his doctor won't help him get his readings down.His doctor just said there is no alternative to Metformin, so if he can't tolerate it, he cannot give him anything else at all.Full stop.I've told him there must be something else he can take to help.
    I think he thinks I'm just a fuss-pot, so what can I do to help? If I had a definite suggestion of an alternative to Metformin, at least that might ease his constantly upset stomach and make his life more bearable.

  2. Pilgrim22

    Get your friend to get his GP to perscribe metformin SR ( slow release) most people who cannot tolerate normal metformin can tolerate this
    Sent from the Diabetes Forum App

  3. dawnmc

    Horrible doctor they don't listen do they!!! SR or MR Metformin is the one to ask for. Can you be there with him?

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